Matches 1 - 50 out of 207 1 2 3 4 5 >


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US20150132737 SYSTEM FOR KEEPING ALIVE AND TRANSPORTING SKIN BIOPSIES AND APPLICATIONS OF SAID SYSTEM  
Disclosed is an in vitro or ex vivo method for preserving and/or keeping alive mammalian, preferably human skin biopsies, enabling to transport it and, if applicable, to culture it. Also disclosed...
US20140193798 CYCLIC IMPLANT PERFUSION, CLEANING AND PASSIVATION PROCESS AND IMPLANT PRODUCED THEREBY  
This invention is a novel method for perfusion of a porous implant which achieves efficient interpenetration of desired factors into and removal of undesirable factors from the pores of the...
US20120214149 CYCLIC IMPLANT PERFUSION, CLEANING AND PASSIVATION PROCESS AND IMPLANT PRODUCED THEREBY  
A method for perfusion of a porous implant which achieves efficient interpenetration of desired factors into and removal of undesirable factors from the pores of the implant, cleaning of the...
US20130280692 INTEGRATED PERFUSION DEVICE  
An integrated perfusion apparatus or device for use in e.g. extracorporeal membrane oxygenation, cardiopulmonary bypass, or isolated organ or limb perfusion, comprises a blood pump for circulating...
US20140030231 METHODS AND COMPOSITIONS FOR PRESERVING TISSUES AND ORGANS  
The present invention generally relates to methods and compositions to determine viability of an organ for transplantation and other medical purposes. One aspect of the invention relates to a...
US20140308653 METHODS AND SYSTEMS FOR ASSESSING EX-VIVO ORGAN HEALTH  
Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while...
US20130323708 ISOLATED ADULT CELLS, ARTIFICIAL ORGANS, REHABILITATED ORGANS, RESEARCH TOOLS, ORGAN ENCASEMENTS, ORGAN PERFUSION SYSTEMS, AND METHODS FOR PREPARING AND UTILIZING THE SAME  
One aspect of the invention provides a method for harvesting adult cells from an organ. The method includes perfusing the organ with a perfusate and isolating adult cells from the organ, thereby...
US20120282591 Compositions and Methods for Tissue Preservation  
Methods and compositions for resuscitating, storing, and preserving functional integrity of organs and tissues. Metabolic function is maintained by sustaining ATP levels, mitochondrial function,...
US20120264103 Compositions And Method For Tissue Preservation  
Methods and compositions for resuscitating, storing, and preserving functional integrity of organs and tissues. Metabolic function is maintained by sustaining ATP levels, mitochondrial function,...
US20100304352 SYSTEMS AND METHODS FOR PRESERVING A HUMAN ORGAN FOR TRANSPLANTATION  
A perfusion pump system for providing perfusate to an organ of a human body includes an actuator coupled to a pump to provide an actuating force to the pump. The pump includes an outlet for...
US20150190548 IMPLANT AND METHOD FOR PRODUCING AN IMPLANT  
The invention relates to an implant derived from intestinal tissue and to an improved method for producing an implant from intestinal tissue. According to the invention, intestinal tissue...
US20140017661 CANNULA  
A cannula includes a first clamping surface on a closing portion of the cannula, a second clamping surface on a base of a cannula, a connecting structure that connects the closing portion and the...
US20120183944 DECELLULARIZATION AND RECELLULARIZATION OF ORGANS AND TISSUES  
The invention provides for methods and materials to decellularize an organ or portion thereof and to recellularize such a decellularized organ or portion thereof to thereby generate an organ or...
US20130017533 Perfusion Culture Method and Perfusion Culture Device for Organ or Tissue  
Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while...
US20130177898 Method of Treating Organs  
A method of treating tissue, including organs, with electromagnetic energy to decrease the fat content of the tissue comprises the steps of providing a source of electromagnetic energy, and...
US20150056601 Cardiopulmonary Apparatus and Methods for Preserving Organ Viability  
Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the...
US20140154663 Process for Devitalizing Soft-Tissue Engineered Medical Implants, and Devitalized Soft-Tissue Medical Implants Produced  
The invention provides methodologies and apparatus for producing devitalized soft-tissue implants where the implant retains metabolically non-viable and/or reproductively non-viable cells, and...
US20140220548 METHODS AND COMPOSITIONS TO MODIFY THE IMMUNOGENICITY OF A VASCULARIZED ORGAN OR TISSUE  
Disclosed herein is an RGD-enriched solubilized extracellular matrix composition derived from endothelial cell culture that can be used to modify the immunogenicity or thrombogenicity of an organ...
US20140127172 METHODS OF PRESERVING FUNCTIONALITY OF AN ORGAN, PRESERVING FERTILITY OF A PATIENT UNDERGOING A TREATMENT EXPECTED TO CAUSE STERILITY AND ASSURING A SUPPLY OF VIABLE GAMETES FOR FUTURE USE  
A method of preserving functionality of an organ is disclosed herein, including removing a whole organ including vasculature from a donor, cryo-preserving the whole organ including vasculature,...
US20150079580 Systems and Methods for Ex Vivo Organ Care  
The invention, in various embodiments, provides systems, methods and solutions for perfusing an organ ex vivo.
US20110136096 Systems and Methods for Ex Vivo Organ Care  
The invention, in various embodiments, provides systems, methods and solutions for perfusing an organ ex vivo.
US20120094268 TISSUE MAINTENANCE  
The invention provides a method of reducing damage to a tissue, organ or cell from surgical procedures comprising administering a composition comprising a potassium channel opener/agonist and/or...
US20140017665 ORGAN TRANSPORTER WITH OXYGEN GENERATION  
An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit;...
US20120179139 Delivery System for Cell-Based Therapies  
A warm perfusion system that has the ability to support a tissue or organ at a near normal metabolic rate provides the mechanism not only for restored oxidative metabolism of the organ but for the...
US20140045167 METHODS FOR EVALUATING THE SUITABILITY OF AN ORGAN FOR TRANSPLANT  
Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while...
US20130189225 METHODS OF INCREASING EFFICIENCY OF VECTOR PENETRATION OF TARGET TISSUE  
Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the...
US20130011823 ORGAN CARE SOLUTION FOR EX-VIVO MACHINE PERFUSION OF DONOR LUNGS  
An ex-vivo lung solution for machine perfusion of donor lungs on OCS. The solution may be mixed with whole blood or packed red blood cells to form the OCS lung perfusion solution.
US20140017666 FILTRATION IN ORGAN PERFUSION APPARATUS  
A filter for filtering perfusate is integrated with an exterior portion of an organ container. The filter may be used in an apparatus for perfusing an organ. The perfusion apparatus may include an...
US20140255904 Modulating ischemic injury and preserving/storing tissue  
The invention is directed to methods of modulating ischemic injury in tissues and organs, including donor tissue and organs and intact tissue and organs. The invention is further directed to...
US20130157248 SYSTEMS AND METHODS FOR EX VIVO LUNG CARE  
Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a...
US20120232014 ANTITHROMBOTIC COMPOUNDS  
A soluble compound for preventing or reducing blood coagulation comprising an antithrombotic agent and a membrane binding element, wherein the antithrombotic agent has a weight of less than about...
US20150030569 METHODS FOR INDUCING IMMUNE TOLERANCE TO ORGAN TRANSPLANTS  
The present invention is directed to methods of treating an organ or a tissue prior to transplantation thereof into a recipient, comprising ablating the cells composing the blood vessels of said...
US20130323709 Treating Heart Tissue  
Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during,...
US20130040281 Procurement of Placental Stem Cells  
Methods and solutions for the preservation and procurement of placental stem cells. A method for collecting stem cells from a placenta comprises: draining cord blood from the placenta; perfusing...
US20100330547 Perfusing an organ with an in situ generated gas  
Method and system for organ preservation. According to one aspect, an organ may be preserved by being perfused with an in situ generated preserving gas. The organ may be, for example, a human or...
US20130203041 PERFUSION SOLUTION  
The invention provides a perfusion stock composition, for preserving a donor organ for transplantation, comprising: a source of 60 to 100 mM Na+; a source of 10 to 20 mM K+; a source of 5 to 10 mM...
US20100311035 Preservation solution for organs and biological tissues  
The invention relates to the field of organ and biological tissue preservation. In particular, the invention relates to machine perfusion or cold storage solutions for the preservation of organs...
US20150175959 POST-PARTUM MAMMALIAN PLACENTA, ITS USE AND PLACENTAL STEM CELLS THEREFROM  
The present invention provides a method of extracting and recovering embryonic-like stem cells, including, but not limited to pluripotent or multipotent stem cells, from an exsanguinated human...
US20110177487 METHODS AND APPARATUS FOR PERFUSION OF AN EXPLANTED DONOR HEART  
Described herein are methods and apparatus that may be used in various applications, such as to extend the viability of a donor heart, promote the efficacy for transportation of a donor heart,...
US20150208643 REPAIRED ORGAN AND METHOD FOR MAKING THE SAME  
A repaired ex vivo organ suitable for transplantation in a human, said repaired ex vivo organ having undergone ex vivo organ perfusion for a maintenance period, wherein said organ had been...
US20120330438 REPAIRED ORGAN AND METHOD FOR MAKING THE SAME  
A repaired ex vivo organ suitable for transplantation in a human, said repaired ex vivo organ having undergone ex vivo organ perfusion for a maintenance period, wherein said organ had been...
US20130130225 COMPOSITION FOR THE COLD STORAGE OF ORGANS  
The present invention relates to a cold organ preservation composition for transplantation comprising a cold organ preservation solution and cardiotrophin-1 or a functionally equivalent variant...
US20110236875 Composition and Method for the Restoration and Preservation of Transplant Organs Procured From DCD Donors  
The present invention provides a perfusion solution comprising specific metabolic agents, antioxidant agents, and membrane stabilizer agents that can help improve preservation, organ viability,...
US20120264104 METHOD FOR THE HYPOTHERMIC PERFUSION OF A CARDIAC ORGAN, AND DEVICE FOR THE IMPLEMENTATION THEREOF  
The present invention relates to a method and device for the hypothermic perfusion of a cardiac organ. According to the invention, the infusion device comprises: a. a first sealed tank (2) that is...
US20120315618 ASSESSING, MAINTAINING AND/OR RESTORING VIABILITY OF ORGANS/TISSUES  
Methods for ex vivo perfusion of organs (and/or tissues) with a perfusate designed to condition the organ with the desired effect being that upon transplant, said organ, having been administered...
US20130171613 Flush preservation solution  
Flush preservation solution for the preservation of cells in the absence of a blood supply comprising: v) water for injection; andvi) at least one saccharide such as a monosaccharide,...
US20120183945 METHOD, DEVICE AND FLUID FOR TREATMENT OF A HEART AFTER HARVESTING  
Method and device for treatment of a heart after harvesting and before transplantation. The device includes a container intended to comprise the heart; a first line for connection to an aorta of...
US20150230453 COMPOSITIONS AND METHODS FOR ORGAN PRESERVATION  
Disclosed herein are solutions for use with machine perfusion of one or more organs. In some embodiments, the solutions comprise acellular cross-linked hemoglobin in a physiologically acceptable...
US20140220550 APPARATUS, SYSTEM AND METHOD FOR CONDITIONING AND PRESERVING AN ORGAN FROM A DONOR  
A donor organ treatment apparatus has a container for holding an organ and a perfusion liquid circuit. The perfusion circuit includes a supply conduit downstream of an oxygenator and a heat...
US20110217689 FLUIDICS BASED PULSATILE PERFUSION PRESERVATION DEVICE AND METHOD  
In one embodiment, a preservation apparatus is described that includes a storage compartment. The storage compartment is configured to hold an organ or tissue and a preservation fluid. A cover...

Matches 1 - 50 out of 207 1 2 3 4 5 >