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US20130122076 Transdermal Patch Having Ultrasound Transducer for Administering Thrombolytic Reagents to Patients Having a Protein Misfolding Disease  
The present invention relates to a method and device for treating patients with a Protein Misfolding Disease by chronically administering an effective dose of a thormbolytic reagent over an...
US20140186423 Transdermal Patch Having Ultrasound Transducer for Administering Thrombolytic Reagents to Patients Having a Protein Misfolding Disease  
The present invention relates to a method and device for treating patients with a Protein Misfolding Disease by chronically administering an effective dose of a thrombolytic reagent and/or a...
US20150086565 CANCER-RELATED EXTRACELLULAR MATRIX SIGNATURES AND RELATED METHODS AND PRODUCTS  
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with...
US20140294843 DIAGNOSIS AND TREATMENT OF COPD  
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a...
US20110123517 DISSOLVABLE PHARMACEUTICAL IMPLANT  
A pharmaceutical implant may include a pharmaceutical and at least one excipient, and may be configured to be implanted in a body of a patient. The at least one excipient may dissolve after...
US20150071879 Stabilization of Aqueous Compositions of Proteins with Displacement Buffers  
An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least...
US20110097367 MONOLITHIC IN-SITU CROSS-LINKED ALGINATE IMPLANTS  
A method of making and using a monolithic alginate implant is described. The implant is formed by providing an uncrosslinked, highly pure and high molecular weight alginate solution and injecting...
US20130202674 TISSUE PATCH  
Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without...
US20070148159 Use of crotoxin as an analgesic - CIP  
A method of producing analgesia and enhancing analgesia is disclosed. The method includes administering a beta-neurotoxin that is characterized by its ability to bind to pre- and postsynaptic...
US20130259854 METHODS AND COMPOSITIONS FOR REDUCING THE INCIDENCE OF POST-SURGICAL ADHESIONS  
The disclosure relates to a method of reducing the incidence of post-surgical adhesions in a subject undergoing surgery. More specifically, the method relates to reducing the incidence of...
US20130028954 HEMOSTATIC DRESSING  
The present invention relates to a hemostatic dressing which comprises a plurality of layers that contain resorbable materials and/or coagulation proteins. In particular, the invention includes...
US20120052054 METHOD FOR PREVENTING SKIN ELASTICITY LOSS BY SUPPRESSING INCREASE OF SUBCUTANEOUS FAT  
A cosmetic method for preventing an aggravation of skin condition accompanied with elasticity loss such as sag and a wrinkle is developed. The invention provides the method for preventing an...
US20140205587 Proteases for Degrading Gluten  
Gluten-degrading proteases can be used to degrade gluten and for making gluten-containing food safer for patients suffering from gluten intolerance.
US20140072547 COSMETIC  
A composition is provided that includes a fish spawn protein isolate. A natural product extract is also present that includes unsaturated fatty acids and sterols. An emulsifier is provided to form...
US20130336948 COSMETIC  
A composition is provided that includes a fish spawn protein isolate. A natural product extract is also present that includes unsaturated fatty acids and sterols. An emulsifier is provided to form...
US20140220103 HEMOSTATIC DRESSING FOR ARTERIAL BLEEDING  
A wound treatment system having a formulation to retard bleeding. In particular, the wound treatment system includes medical device, e.g. bandage, which can be adapted for internal or external...
US20130078302 Protein C Zymogen and Methods of Use Thereof to Prevent Cancer Metastases  
Compositions and methods useful for the inhibition of cancer metastasis are disclosed.
US20120156265 CONFORMABLE TISSUE REPAIR IMPLANT CAPABLE OF INJECTION DELIVERY  
A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of...
US20110286937 SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME  
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
US20140086872 Methods of Treating a Subject for a Condition  
Methods are provided for treating a subject for at least one condition that includes inflammation, a blood clotting condition and autonomic nervous system dysfunction such as adrenergia, e.g.,...
US20120195883 MONOCOT SEED PRODUCT COMPRISING A HUMAN BLOOD PROTEIN  
The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and...
US20150150822 NOVEL CORE-SHELL NANOPARTICLES FOR ORAL DRUG DELIVERY  
The invention relates to an oral nanoparticle drug delivery system, including methods for preparing such a system using a hydrophobic water insoluble protein, which nanoparticles may include...
US20150175994 HEAT-INACTIVATED COMPLEMENT FACTOR B COMPOSITIONS AND METHODS  
The present disclosure is directed to compositions comprising heat-inactivated complement factor B and methods of using the same to treat thrombotic or complement-mediated inflammatory disorders.
US20140227350 Annexin A2 and Tissue Plasminogen Activator For Treating Vascular Disease  
The use of tPA to treat hemorrhagic transformation, neurotoxicity has been limited to short treatment time windows because a high dose of tPA required to generate sufficient amounts of the enzyme...
US20140154234 METHOD FOR GENERATING THROMBIN  
Methods of generating thrombin and methods of applying a clotting tissue sealant to a site on a subject are provided. A blood component comprising platelets can be obtained from the subject. A...
US20120027746 METHOD FOR GENERATING THROMBIN  
Methods of generating thrombin and methods of applying a clotting tissue sealant to a site on a subject are provided. A blood component comprising platelets can be obtained from the subject. A...
US20150134049 Methods for Tissue Passivation  
Methods of tissue passivation are described herein for use in preserving normal tissue architecture, reducing post-surgical inflammation, and reducing or preventing the development of pathogenic...
US20130189243 BIOMARKERS FOR ACUTE ISCHEMIC STROKE  
The present invention provides methods and compositions for the diagnosis of acute ischemic stroke. The invention further provides methods and compositions for distinguishing acute ischemic stroke...
US20120148658 SOLID DRESSING FOR TREATING WOUNDED TISSUE  
Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of fibrinogen and a fibrinogen activator,...
US20140086899 DIAGNOSTIC AND PROGNOSTIC ASSAY FOR A CONDITION OR EVENT OF THE VASCULAR SYSTEM  
The present disclosure relates generally to the field of diagnostic and prognostic assays for a condition or event of a vascular system such as the cerebrovascular system. An assay is taught...
US20130315891 FORMULATIONS OF HUMAN TISSUE KALLIKREIN-1 FOR PARENTERAL DELIVERY AND RELATED METHODS  
Provided are high concentration compositions of tissue kallikrein-1 (KLK1) and methods of parenterally administering such compositions to a subject in need thereof, where absorption into the...
US20130149343 Hemostatic Bioabsorbable Device with Polyethylene Glycol Binder  
A hemostatic pad comprising a bioabsorbable scaffolding material; a lyophilized thrombin powder, a lyophilized fibrinogen powder, and a meltable binder powder, with all powders disposed on the...
US20140127185 METHODS AND COMPOSITIONS USING NEUROPROTECTIVE STEROIDS AND THROMBOLYTIC AGENTS  
Described herein are compositions and methods for treating or preventing ischemic injury. In particular, the methods and compositions relate to the use of a neuroprotective steroid, such as...
US20120070471 ADMINISTRATION OF ENOXOPARIN SODIUM TO PATIENTS 75 YEARS AND OLDER WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION  
Methods for treating ST-segment elevation myocardial infarction in a human patient 75 years of age or older. The methods comprise administering a dose of less than 1 mg per kg body weight, about...
US20130243855 Modified coagulation factor IX polypeptides and use thereof for treatment  
Provided are modified factor IX (FIX) polypeptides and methods of generating modified FIX polypeptides. Also provided are pharmaceutical compositions, including compositions formulation for oral...
US20130336956 RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF  
The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins. Described are recombinant methods for...
US20110008315 RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF  
The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins. Described are recombinant methods for...
US20120308550 Method of Using Fish Plasma Components to Promote Functional Recovery in the Mammialian CNS  
A method includes applying thrombin and salmon fibrinogen to injured motor neurons at a central nervous system injury site, thereby enhancing repair and functional recovery of the injured motor...
US20140248258 METHODS FOR IMPROVING GUT HEALTH  
The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins,...
US20120225050 METHODS FOR IMPROVING GUT HEALTH  
The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins,...
US20110171200 PROTEIN C RS2069915 AS A RESPONSE PREDICTOR TO SURVIVAL AND ADMINISTRATION OF ACTIVATED PROTEIN C OR PROTEIN C-LIKE COMPOUND  
Provided herein are methods, oligonucleotides and peptide nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C-like compound...
US20150071909 METHODS AND COMPOSITIONS FOR REDUCING THE INCIDENCE OF POST-SURGICAL ADHESIONS  
The disclosure relates to a method of reducing the incidence of post-surgical adhesions in a subject undergoing surgery. More specifically, the method relates to reducing the incidence of...
US20130071375 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION  
The present invention provides methods for treating sepsis comprising administering to an individual an effective amount of a chimeric protein.
US20110229454 Use of Prourokinase and Variants Thereof in Facilitated Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction  
In the field of biological medicines, a use of prourokinase (proUK) and variants thereof in facilitated percutaneous coronary intervention (PCI) in patients with acute myocardial infarction is...
US20150125440 METHOD FOR IMPROVED FIBRIN SEALING  
The present invention relates to a fibrin matrix, its preparation and use for effectively sealing a defect in a mucosa or other moist tissue.
US20110182991 METHOD FOR IMPROVED FIBRIN SEALING  
The present invention relates to a fibrin matrix, its preparation and use for effectively sealing a defect in a mucosa or other moist tissue.
US20140219990 WOUND CLEANING CHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING  
A wound cleaning chemical composition that includes 2 gs natural salt in 100 mls of water forming a natural salt solution, 50 mgs lactoferrin in 100 mls of water forming a lactoferrin solution, 2...
US20120064075 CHIMERIC FACTOR VII MOLECULES WITH ENHANCED HALF LIFE AND METHODS OF USE  
The present invention relates to novel proteins and methods of using chimeric Factor VIIa polypeptides.
US20100310544 COMPOSITION COMPRISING CALCIUM IONS AND AT LEAST ONE PROTEOLYTIC ENZYME FOR USE IN THE IN VITRO AND IN VIVO REGENERATION OF CUTANEOUS AND CONNECTIVE TISSUES  
The invention is based on the finding that calcium ions and proteolytic enzymes, particularly papain, act in a synergetic way in the regeneration of skin and connective tissues. Thus, such a...
US20140120078 FRAGMENTED POLYMERIC COMPOSITIONS AND METHODS FOR THEIR USE  
Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and...