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US20080107640 |
BIOLOGICAL PESTICIDE
Methods for exterminating pests using compositions comprising at least one protease enzyme. A detergent component may also be utilized in such compositions.
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US20080095759 |
Defense and Counter-Defense Compositions and Methods
Contemplated compositions and methods are directed to the use of a proteinase to reduce capsaicin-induced pain sensation in a mammal. Preferably, the proteinase comprises a bromelain preparation in...
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US20080095758 |
Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
The present invention is directed stromal cell derived factor-1 peptides that have been mutated to make them resistant to digestion by the proteases dipeptidyl peptidase IV (DPPIV) and matrix...
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US20080095756 |
Compositions Comprising Lysostaphin Variants And Methods Of Using The Same
The present invention relates to compositions comprising lysostaphin variants and methods of using the same. In particular, the present invention provides de-immunized lysostaphin variants and...
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US20080095710 |
ENZYME TREATMENT OF FOODSTUFFS FOR CELIAC SPRUE
Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of...
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US20080089869 |
PROAEROLYSIN CONTAINING PROTEASE ACTIVATION SEQUENCES AND METHODS OF USE FOR TREATMENT OF PROSTATE CANCER
Disclosed herein are modified proaerolysin (PA) peptide. In some examples, the proteins include a prostate-specific protease cleavage site and can further include a prostate-tissue-specific binding...
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US20080075709 |
Pharmaceutical Composition Comprising Factor VII Polypeptides And Thrombomodulin Polypeptides
The present invention relates to a composition comprising factor VII or a factor VII-related polypeptide and thrombomodulin or a thrombomodulin-related polypeptide, and the use thereof for treating...
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US20080069846 |
Protease, a Gene Therefor and the Use Thereof
The present invention relates to a protease, and more specifically to a protease derived from Aranicola proteolyticus, a gene coding for said enzyme, a gene expression system for said protease, a...
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US20080057050 |
Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
The invention refers to the use of non-neurotoxic plasminogen activating factors, e.g., from Desmodus rotundus (DSPA) or genetically modified plasminogen activating factors, for example of human...
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US20080044459 |
Enzymatic debridement therapy for abnormal cell proliferation
Compositions and methods are provided to destroy internal cancerous lesions selectively by the administration of a combination of a debridement protease enzyme and a denaturant of cell structural...
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US20080044401 |
DRUG THERAPY FOR CELIAC SPRUE
Administering an effective dose of a tTGase inhibitor to a Celiac or dermatitis herpetiformis patient reduces the toxic effects of toxic gluten oligopeptides, thereby attenuating or eliminating the...
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US20080044400 |
Targeted enzyme prodrug therapy
The present invention provides targeted enzymes that bind to targets better than the corresponding pre-targeted enzymes bind the target under like conditions, methods of making targeted enzymes,...
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US20080044378 |
Methods and Compositions for Protein Production Using Adenoviral Vectors
The present invention provides methods and compositions for recombinant protein production through replication-defective adenoviral vector infection of non-trans-complementation cell lines. Thus,...
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US20080020036 |
Controlled release formulations of enzymes, microorganisms, and antibodies with mucoadhesive polymers
There is provided a composition comprising at least one mucoadhesive polymer that is capable of forming a hydrogel and at one least water soluble polymer, and one or more enzymes, microorganisms,...
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US20080014190 |
Proteinases destroy cancer tumor's solid structure and kill cancer cells locally
A proteinase therapy has been invented to eliminate solid-tumors by destroying tumors' solid structure and killing cancer cells by cleaving vital extracellular matrix proteins C-terminally,...
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US20080008697 |
Polynucleotides encoding novel PCSK9 variants
The present invention provides novel polynucleotides encoding PCSK9b and PCSK9c polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant...
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US20080003214 |
Medicaments Comprising Carbonyl Compounds, And The Use Thereof
Use of compounds of the formula (I) in which D, E, G, W, X, Y, T, R 1 and R 2 have the meaning indicated in Patent Claim 1 , for the prophylaxis and/or therapy of thromboembolic diseases
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US20080003200 |
GRP78 targeting peptides and methods employing same
The compositions and methods include targeting peptides selective for tissue selective binding, particularly prostate and/or bone cancer, or adipose tissue. The methods may comprise targeting...
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US20080003198 |
Hernia treatment agents
There are provided herniated disc treatment agents developed as a result of molecular level analysis of the action mechanism of spontaneous resorption of herniated disc. Angiogenesis-inducing...
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