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US20090311236 |
Therapeutic Peptide Compositions And Methods Of Making And Using Same
Therapeutic compositions include peptide formulations having a mixture of serum, albumin, casein, peptone, pacreatin, and sodium hydroxide. The peptide compositions do not include nucleic acid or...
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US20090304668 |
LARVAL POLYPEPTIDES HAVING A NUCLEASE ACTIVITY
This invention relates to a polypeptide obtainable from insect larvae, such as those from Lucilia sericata , and which have activity as a nuclease in that they are able to degrade, denature,...
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US20090304665 |
Super fast-acting insulin compositions
Provided are combinations, compositions and kits containing an fast-acting insulin composition and a hyaluronan degrading enzyme composition formulated for parenteral administration. Such products...
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US20090304765 |
R-RAS ACTIVITY IN VASCULAR REGULATION
The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent...
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US20090297497 |
Methods and compositions for treating nephrogenic diabetes and insipidus
Disclosed are compositions and methods for treating nephrogenic diabetes insipidus and for induction of diuretic effect.
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US20090297592 |
Lipid Vesicle Composition
It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can...
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US20090280105 |
Novel Fungal Enzymes
This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such...
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US20090274682 |
DEMETHYLATION AND INACTIVATION OF PROTEIN PHOSPHATASE 2A
Embodiments of the present invention relate to atomic coordinates for PME-1 alone or in complex with PP2A, as well as methods for using these atomic coordinates to prepare inhibitors of PME-1...
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US20090263372 |
PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF THE SYMPTOMS OF ADDICTION AND METHOD OF DIAGNOSING SAME
A therapeutic agent for the treatment of the symptoms of addiction and the method for preparing the therapeutic agent is disclosed. The therapeutic agent is a stable pharmaceutical preparation...
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US20090263371 |
Use Polysaccharides for Promotion of Enzymatic Activity
This disclosure provides methods and compositions for the promotion of enzymatic activity of Target Enzymes, including but not limited to oligosaccharide/polysaccharide enzymes, protein enzymes,...
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US20090258000 |
MUCOSALLY NON-IRRITATIVE AMPHOTERICIN B FORMULATIONS AND METHODS FOR TREATING NON-INVASIVE FUNGUS-INDUCED MUCOSITIS
The present invention is directed to compositions and methods for non-irritatively treating and preventing non-invasive fungus-induced mucositis. Specifically, the invention involves compositions...
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US20090252719 |
USE OF FRUCTANASES IN FEED OF HOOFED ANIMALS, PREFERABLY TO PREVENT DISEASES
Laminitis is defined as an inflammation of the sensitive laminae of the hoof, especially in horses. It has been surprisingly found that fructanases such as 2,1-β-D-fructan hydrolase are highly...
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US20090246189 |
Methods for Promoting Neurite Outgrowth and Survival of Dopaminergic Neurons
The present invention relates generally to methods for promoting regeneration, outgrowth and survival of dopaminergic neurons comprising contacting said dopaminergic neurons with an effective...
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US20090238887 |
Highly Impact-Resistant Granules
The present invention provides highly impact-resistant, water-soluble or water dispersible, low-dust granules comprising an active ingredient and methods for obtaining the same.
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US20090232853 |
TREATMENT OF LAMINITIS
The present invention provides a composition comprising one or more of a matrix metalloprotease inhibitor, a de-carboxylase inhibitor, a fructanase enzyme and/or a flavonoid for use in the...
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US20090220481 |
METHOD AND COMPOSITIONS FOR TREATING SKIN
A skin care composition comprising at least one keratinocyte CLOCK or PER1 gene activator and at least one DNA repair enzyme; a method for inhibiting damage to human keratinocytes due to...
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US20090220480 |
CELLULOLYTIC ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
The invention provides polypeptides having any cellulolytic activity, e.g., a cellulase activity, a endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a β-xylosidase,...
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US20090214511 |
DIGESTIBLE COMPOSITIONS OF INULIN FOR MANAGING BLOOD GLUCOSE LEVELS
Digestible compositions of inulin for managing blood glucose levels in a patient are disclosed. The compositions can include an inulin, a sucrose and an amylase, wherein the inulin is configured to...
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US20090202516 |
INHIBITION AND TREATMENT OF GASTROINTESTINAL BIOFILMS
Orally administered physiologically acceptable anti-biofilm compositions comprising enzymes and if desired additional components such as antimicrobials, antibiotics, antifungals, herbals, chelating...
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US20090202514 |
AGENTS FOR IMPROVING CHRONIC OBSTRUCTIVE PULMONARY DISEASES
The present invention relates to agents for suppressing pulmonary emphysematous lesions and agents for suppressing emphysematous lesions which are suitable for treating and/or preventing COPD,...
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US20090202515 |
AGENTS FOR SUPPRESSING NEURAL FIBROTIC DEGENERATION
The present invention examined the accumulation of chondroitin sulfate proteoglycans (CSPGs). The present invention relates to neurodegeneration-suppressing agents that are suitable for gene...
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US20090191178 |
Manufacture of Highly Phosphorylated Lysosomal Enzymes and Uses Thereof
This invention provides compositions of highly phosphorylated lysosomal enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal enzymes and compositions and...
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US20090162340 |
STABLE GALENIC FREEZE-DRIED PHARMACEUTICAL PREPARATION OF RECOMBINANT CARBOHYDRATE-BINDING POLYPEPTIDES
The invention relates to a method for the production of a medicament containing a polypeptide comprising at least one recombinant carbohydrate-binding polypeptide, or a functional fragment or...
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US20090162439 |
SILK FIBROIN COATING
The present invention is directed to compositions and methods for preventing or inhibiting biofilm formation on a solid substrate comprising an antimicrobial agent and a biofilm-degrading enzyme...
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US20090155238 |
XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or...
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US20090148433 |
METALLO-PROTEIN AND TOCOTRIENOL (MP-T3) COMPOSITIONS AND USES THEREOF
Metallo-proteins including but not limited to lactoferrin (LF), transferrin (TF) and ovotransferrin (OTF) (all members of transferrin family), ceruloplasmin (CP) and metallo-thionein (MT) were...
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US20090148432 |
COMPOSITIONS FOR INHIBITING ATHEROSCLEROSIS
The present invention relates to compositions and methods for the reduction of atherosclerotic plaques and the decrease in the level of total serum cholesterol, triglycerides, serum LDL...
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US20090142327 |
Novel Class of Therapeutic Protein Based Molecules
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that...
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US20090130692 |
Use of microproteins as tryptase
Disclosed are uses of microproteins preferably microproteins forming a cystine knot (i.e. belonging to the family of inhibitor cystine knot (ICK) polypeptides) or polynucleotides encoding said...
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US20090130081 |
Method for treating pervasive development disorders
A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme administration to such individuals, and...
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US20090130082 |
Compositions and methods for the treatment and prevention of infections caused by staphylococcus aureus bacteria
The present invention relates to antimicrobial deoxyribonuclease-based compositions that inhibit growth and proliferation of Staphylococcus aureus bacteria. The present invention also relates to...
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US20090123451 |
SLOW INTRAVENTRICULAR DELIVERY
Neurological diseases, including lysosomal storage diseases, can be successfully treated using intraventricular delivery of the therapeutic agents to bypass the blood-brain barrier. Similarly,...
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US20090117091 |
Methods for treating pompe disease
The present invention provides methods for treating Pompe disease in a subject by administering to the subject a therapeutically effective amount of a fusion protein which includes human acid...
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US20090104173 |
NOVEL PROCESS FOR SOLUBILIZING PROTEIN FROM A PROTEINACEOUS MATERIAL AND COMPOSITIONS THEREOF
The process for solubilizing proteinaceous material of the present invention includes subjecting the proteinaceous material to a sufficient amount of a basic solution to obtain a supernatant that...
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US20090104147 |
Sialoadhesin-Related Compositions and Methods
Methods of delivering a cargo moiety to a cell is provided according to embodiments of the present invention which includes contacting a cell expressing sialoadhesin with a conjugate including a...
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US20090098064 |
METHOD OF TREATING PULMONARY EDEMA OR PULMONARY INFLAMMATION
The invention provides a method for preventing or treating pulmonary edema and/or pulmonary inflammation in a subject by the administration of at least one nucleotidase. The subject is preferably a...
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US20090081184 |
NON-PANCREATIC PROTEASES FOR CONTROLLING PLASMA CHOLECYSTOKININ (CCK) CONCENTRATION AND FOR TREATING PAIN
This invention relates to methods for maintaining the basal level or reducing the level of cholecystokinin (CCK) in blood plasma of a mammal. Additionally, the invention provides methods for...
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US20090068167 |
COMPOSITIONS FOR PROMOTING WOUND HEALING AND TREATING PSORIASIS
The present invention relates to compositions and methods for promoting healing of cutaneous, mucosal and/or mucocutaneous lesions associated with the presence of a mycoplasma and one or more...
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US20090047232 |
FORMULATION AND METHOD FOR TREATING ANIMAL WASTE
The invention is directed to a formulation and method for treating solid waste from animals. The formulation comprises a surfactant having antimicrobial activity, preferably a cationic surfactant,...
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US20090047309 |
COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN
The present invention relates to methods and compositions for repairing adverse effects of the environment, daily stress, sun exposure, or pre-mature aging on human skin, comprising applying to the...
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US20090047272 |
Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases
Antiviral compositions comprising a modified nuclease, or a plurality of such modified nucleases having at least one non-natural amino acid residue substituted for a naturally occurring amino acid...
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US20090041741 |
MODIFIED ENZYME AND TREATMENT METHOD
There is disclosed an isolated, modified recombinant β-glucuronidase wherein the modification is having its carbohydrate moeties chemically modified so as to reduce its activity with respect to...
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US20090035293 |
Amylases for Pharmaceutical Use
The pharmaceutical use of amylases related to Bacillus alpha-amylases of SEQ ID NOs: 1-3, optionally in combination with a lipase and/or a protease. Examples of medical indications are: Treatment...
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US20090028829 |
Fusion proteins for the treatment of CNS
This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including...
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US20090010914 |
Use of Oligouronates for Treating Mucus Hyperviscosity
The invention provides a method of treatment of a human or non-human subject to combat mucosal hyperviscosity in the respiratory tract, which method comprises application to a mucosal surface in...
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US20090012494 |
INTRADERMAL DELIVERY OF BIOLOGICAL AGENTS
The present invention relates to methods for intradermally delivering one or more biologically active agents such as vaccines and therapeutic agents into the dermis layer of the skin of a subject...
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US20080317667 |
Compositions and methods for inhibiting growth of smad4-deficient cancers
The present invention is in the fields of cell biology, immunology and oncology. The invention relates to the discovery that there is a relationship between the expression levels of the tumor...
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US20080311192 |
Enteric-Coated Glucosinolates And Beta-Thioglucosidases
The present invention relates to a particulate composition comprising enteric-coated glucosinolate and beta-thioglucosidase particles. The present invention further provides a method of converting...
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US20080286375 |
Method for Preparing Sustained-Release Microparticles Comprising Sucrose Acetate Isobutyrate
A sustained release microparticles which is capable of releasing a protein drug continuously over a long period of time without initial burst release of the drug can be simply prepared by a method...
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US20080286253 |
Composition Comprising Polymeric Material And Uses Thereof
Compositions for the selective delivery of an agent comprising an uncrosslinked starch modified by an acidic group and an agent are described. The compositions are substantially resistant to...
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