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US20110286937 |
SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
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US20110002908 |
TREATMENT OF A-GALACTOSIDASE A DEFICIENCY
The invention provides methods of treating α-galactosidase A deficiency. Dosage forms, methods of administration, and methods of analyzing human α-galactosidase A are also included.
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US20110250181 |
HUMAN LYSOSOMAL PROTEINS FROM PLANT CELL CULTURE
A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or...
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US20120093802 |
BIOACTIVE COMPOSITION INCLUDING STABILIZED PROTEIN AND PROCESS FOR PRODUCING THE SAME
A bioactive composition includes a porous hydrogel matrix. At least one protein is immobilized in the porous hydrogel matrix forming a hydrogel protein composite that is stable in an organic...
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US20110033461 |
Combination Therapy for the Treatment of Cancer
Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed.
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US20120114627 |
DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS CHARACTERIZED BY UNDESIRABLE CELL PROLIFERATION
The present invention relates to compositions and methods for the reduction of atherosclerotic plaques and the decrease in the level of total serum cholesterol, triglycerides, serum LDL...
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US20120039985 |
DENDRITIC CELL MODULATION IN POST-ISCHEMIC WOUNDS
Compositions and methods useful for targeted depletion or modulation of dendritic cells are provided. The compositions and methods can be used to promote healing of ischemia-related injury,...
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US20100310545 |
Dry treatment mixture and methods of production and use
A dry treatment mixture is provided including: a quantity of a dry formulation of a salt; and a quantity of a dry formulation of lysozyme. The salt preferably is sea salt. The dry treatment mixture...
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US20110318327 |
TREATMENT OF SANFILIPPO SYNDROME TYPE B
Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A...
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US20110236366 |
PRODUCTION AND USES OF TYPE I RIBOSOME INACTIVATING PROTEINS
Described herein are methods to express and purify recombinant type 1 ribosome inactivating proteins. Included are methods for using recombinant cucurmosin as a therapeutic to treat cancer and...
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US20110070219 |
HIGH PRESSURE PROTEIN CRYSTALLIZATION
The present disclosure provides an effective method for the crystallization of proteins at high pressure. A preferential excluding agent, and optionally other reagents may be incorporated into the...
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US20100158889 |
ENHANCING THE EFFECT OF THERAPEUTIC PROTEINS ON THE CENTRAL NERVOUS SYSTEM
The present invention provides a polypeptide therapeutic agent, useful in enzyme replacement therapy, with increased therapeutic benefits for the central nervous system. The invention provides a...
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US20110196319 |
COMPOSITION AND SYSTEM FOR WOUND DECONTAMINATION
The present disclosure is directed to a cleansing solution and system for administering the cleansing solution to decontaminate a wound surface. A method and kit for decontaminating a wound surface...
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US20100151009 |
FORMULATIONS FOR DELIVERING INSULIN
Oral insulin formulations and processes for preparing oral insulin formulations are provided.
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US20100330062 |
KLOTHO PROTEIN AND RELATED COMPOUNDS FOR THE TREATMENT AND DIAGNOSIS OF CANCER
Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic...
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US20110142818 |
COMBINATION ENZYME REPLACEMENT AND SMALL MOLECULE THERAPY FOR TREATMENT OF LYSOSOMAL STORAGE DISEASES
This invention provides various combinations of enzyme replacement therapy, gene therapy, and small molecule therapy for the treatment of lysosomal storage diseases.
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US20110070220 |
Immunomodulating gene therapy
The present invention relates, in general, to Pompe disease and, in particular, to a methods of treating Pompe disease and to compounds/constructs suitable for use in such methods.
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US20110135708 |
DIETARY SUPPLEMENT - LIQUID FILLED GUM
A new chewing gum comprising a gum member, with a central core or cavity, and a core element located within the central core or cavity. The chewing gum also comprises a dietary supplement, which...
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US20110091414 |
STABILIZED COMPOSITIONS OF PROTEINS HAVING A FREE THIOL MOIETY
Compositions of proteins having free thiols, and methods of making and using such compositions, are described.
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US20100303797 |
Use of p97 As An Enzyme Delivery System For The Delivery of Therapeutic Lysosomal Enzymes
The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering from a lysosomal storage...
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US20120058132 |
Treatment of glycogen storage disease type II
Methods of treating glycogen storage disease type II, by administering acid α-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.
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US20100183578 |
NITROPROTEIN BIOMARKERS FOR COPD
Specific nitroprotein biomarkers may be used as prognostic and diagnostic tools for COPD. Identification of certain specific nitroprotein biomarkers allows the development of targeted therapies...
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US20120023616 |
METHODS FOR PREVENTING OR INHIBITING MICROBIAL INFECTION OF PLANTS AND PLANT EXHIBITING RESISTANCE TO MICROBIAL INFECTION
This invention provides a method for preventing or inhibiting infection with a plant-infecting microorganism and imparting resistivity to plants, a method for preparing plants having resistance to...
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US20110182875 |
NOVEL CLASS OF THERAPEUTIC PROTEIN BASED MOLECULES
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that...
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US20080187525 |
Formulations Including Digestive Enzymes and Polysorbate Surfactants that Enhance the Colonization of Administered Probiotics Microoganisms
Disclosed are formulations for enhancing the in vivo colonization of probiotic microorganisms that include digestive enzymes and probiotic microorganisms, and polysorbate surfactants. The enzymes...
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US20110280853 |
COMPOSITIONS AND METHODS FOR TREATMENT OR PREVENTION OF STAPHYLOCOCCUS AUREUS INFECTIONS AND FOR THE ERADICATION OR REDUCTION OF STAPHYLOCOCCUS AUREUS ON SURFACES
Compositions and methods for treating or preventing S. aureus infections are provided. The compositions can be formulated as pharmaceutical compositions or as disinfectants, sanitizers, detergents...
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US20120027848 |
Enzyme Delivery Systems and Methods of Preparation and Use
This invention relates to coated digestive enzyme preparations and enzyme delivery systems and pharmaceutical compositions comprising the preparations. This invention further relates to methods of...
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US20120070417 |
ANTI-INFLUENZA FORMULATIONS AND METHODS
The invention relates to pharmaceutical compositions that contain a calcium salt as an active ingredient and also comprise another anti-influenza agent, and to methods for treating or preventing...
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US20110182818 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF SYMPTOMS OF NEUROLOGICAL AND MENTAL HEALTH DISORDERS
A therapeutic composition for the treatment of the symptoms of neurological and mental health disorders, such as Alzheimer's, bipolar disorder, obsessive compulsive disorder, and oppositional...
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US20110104141 |
Methods for Preventing, Removing, Reducing, or Disrupting Biofilm
The present invention relates to methods for preventing, removing, reducing, or disrupting biofilm present on a surface, comprising contacting the surface with an alpha-amylase derived from a...
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US20110081394 |
METHODS OF ATTACHING A MOLECULE-OF-INTEREST TO A MICROTUBE
Provided is a method of attaching a molecule-of-interest to a microtube, by co-electrospinning two polymeric solutions through co-axial capillaries, wherein a first polymeric solution of the two...
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US20100330173 |
COMPOUNDS AND METHODS FOR TREATING INFLUENZA
This invention is directed to methods for treating and preventing influenza infection by inhibiting influenza virus HA maturation processes employing compounds of formula I. It is also directed to...
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US20110305737 |
Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
A comprehensive, single agent cosmetic cream or lotion containing a high number of ingredients that target anti-aging in a defined manner. The cream or lotion contains a high number and variety of...
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US20120076767 |
PROCESS FOR CONCENTRATION OF A POLYPEPTIDE
The present invention comprises a method of concentrating a composition comprising a polypeptide of interest and the use of such a concentrated composition for the treatment of diseases in mammals,...
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US20110182986 |
CONTROLLED RELEASE COMPOSITION
An improved composition for controlling the release profile of an active compound through the intestinal tract comprises particles, especially pellets, containing the active compound, which are...
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US20090304665 |
Super fast-acting insulin compositions
Provided are combinations, compositions and kits containing an fast-acting insulin composition and a hyaluronan degrading enzyme composition formulated for parenteral administration. Such products...
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US20100322915 |
Protease Variants for Pharmaceutical Use
The invention relates to novel variants of a protease derived from Nocardiopsis sp. (SEQ ID NO: 1) and closely related proteases, as well as their pharmaceutical use. The variants show improved...
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US20110059062 |
USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN AIRWAY PASSAGES
A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia cause by Mycoplasma pneumoniae. In general, the composition comprises: (1) a...
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US20120058190 |
FOOD CONTAINING PROLACTIN
A nutritional Composition for a subject, comprising prolactin identical or similar or analogous to prolactin found in a natural food source, and at least one protective layer, wherein release of...
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US20100297148 |
CD38 MODULATED CHEMOTAXIS
The present invention relates to methods for modulating the migratory activity of cells expressing CD38 for the treatment of disorders including, but not limited to, inflammation, ischemia, asthma,...
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US20110076233 |
Delivery System for Cytotoxic Drugs by Bispecific Antibody Pretargeting
The present invention relates to methods and compositions for pretargeting delivery of therapeutic agents. In preferred embodiments, the pretargeting method comprises: a) administering a bispecific...
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US20110091442 |
NOVEL COMPOSITIONS FOR PREVENTING AND/OR TREATING LYSOSOMAL STORAGE DISORDERS
The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing...
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US20120070504 |
PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF THE SYMPTOMS OF ADDICTION AND METHOD OF DIAGNOSING SAME
A therapeutic agent for the treatment of the symptoms of addiction and the method for preparing the therapeutic agent is disclosed. The therapeutic agent is a stable pharmaceutical preparation...
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US20090214511 |
DIGESTIBLE COMPOSITIONS OF INULIN FOR MANAGING BLOOD GLUCOSE LEVELS
Digestible compositions of inulin for managing blood glucose levels in a patient are disclosed. The compositions can include an inulin, a sucrose and an amylase, wherein the inulin is configured to...
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US20100196345 |
PRODUCTION OF HIGH MANNOSE PROTEINS IN PLANT CULTURE
A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or...
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US20060029656 |
Replacement enzyme cochleates
Disclosed are cochleates and cochleate compositions that associated with an replacement enzyme component and/or a plasmid component that encodes a replacement enzyme. Also disclosed are methods of...
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US20110300201 |
DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE
The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a...
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US20050100535 |
Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
The invention relates generally to digestive disorders, and in particular to methods for treating irritable bowel syndrome by increasing carbohydrate absorption by administering a composition...
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US20110178488 |
Sexual Hygienic Composition
The invention is a sexual hygienic preparation comprising extract prepared from the milk of at least one equid animal. The preparation may contain medically/therapeutically acceptable additive(s)...
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US20120036599 |
NOVEL FUNGAL ENZYMES
This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such...
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