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US20090202638 |
BMP GENE AND FUSION PROTEIN
This invention relates to BMP fusion genes, BMP fusion proteins, and methods for making BMP fusion genes and BMP fusion proteins. The invention further relates to methods for treatment using BMP...
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US20090130066 |
AUGMENTATION AND REPAIR OF SPHINCTER DEFECTS WITH CELLS INCLUDING MUSCLE CELLS
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
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US20090074729 |
AUGMENTATION AND REPAIR OF SPINCTER DEFECTS WITH CELLS INCLUDING FIBROBLASTS
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
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US20090016996 |
HAIR MESENCHYMAL CELLS
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
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US20080267923 |
HAIR UNDIFFERENTIATED CELLS
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
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US20080166324 |
PLASMA-DEPLETED, NON-RED BLOOD CELL-DEPLETED CORD BLOOD COMPOSITIONS AND METHODS OF USE
The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are...
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US20080118569 |
Injectable microspheres for tissue construction
The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue...
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US20080118522 |
Naturally occuring IgM antibodies that bind lymphocytes
Human and animal serum contains naturally occurring autoantibodies that develop at birth in absence of deliberate immunization. These antibodies are predominantly of IgM isotype but can include all...
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US20080118479 |
Cell Lines
The present invention relates to cells obtainable from cell lines having the ECACC Accession Nos 04091601, 04110301 and 04092302.
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US20080112998 |
Innovative bottom-up cell assembly approach to three-dimensional tissue formation using nano-or micro-fibers
The present invention provides a synthetic tissue scaffold, the scaffold comprising alternating layers of electrospun polymers and mammalian cells sandwiched within. A novel method is also provided...
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US20080112996 |
Bone cell delivery device
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
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US20080112936 |
Methods of implanting mesenchymal stem cells for tissue repair and formation
The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the...
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US20080112935 |
Augmentation and repair of spincter defects with cells including fibroblasts
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
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US20080107633 |
Cultures of human CNS neural stem cells
The invention provides a cell culture including proliferating human neural stem cells with a doubling rate faster than thirty days. The invention also provides a cell culture media for...
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US20080103605 |
Autologous Bone Graft Material
This invention relates to a musculoskeletogenic MSG graft composite made from whole bone marrow aspirate BMA having native levels of musculoskeletal progenitor cells MSPCs, comprising: a) a...
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US20080102059 |
Treatment for arthritis
The insertion of a growth factor in the body of a human patient is used to treat arthritis. A reduction of inflammation occurs; and in the avascular necrosis type of arthritis, blood vessels and/or...
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US20080095774 |
Agents and Methods for Specifically Blocking CD28-Mediated Signaling
The instant invention provides compositions and methods for downmodulation of immune responses, e.g., autoimmune responses. For example, methods of downmodulating an immune response using agents...
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US20080095751 |
Atherosclerosis
The present invention relates, in general, to atherosclerosis and, in particular, to a method of treating atherosclerosis and to cells suitable for use in such a method.
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US20080095750 |
USE OF ADIPOSE-DERIVED STEM CELLS FOR TREATMENT OF LEUKODYSTROPHIES
The present invention relates to a treatment of a leukodystrophy by administration of an adipose-derived stem cell. Specifically, the present invention relates to the treatment of Krabbe disease...
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US20080095749 |
Mesenchymal stem cells and uses therefor
Methods of treating autoimmune diseases, allergic responses, cancer, inflammatory diseases, or fibrosis in an animal, promoting would healing, repairing epithelial damage and promoting angiogenesis...
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US20080095747 |
Promotion of Cell Migration and Axon Regeneration in the Cns
The present invention relates broadly to methods for stimulating neural progenitor cell migration to certain regions of the nervous system where the neural progenitor cell naturally would not...
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US20080095709 |
Method and apparatus for installation of dental implant
An organ derived from genetic material is inserted in a patient's body. Genetic material is inserted at a selected site in the body to grow an organ.
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US20080089873 |
Method for Regenerating Hair Follicles by Suppressing a Gene with Hair Follicle Formation-Inhibiting Ability or by Activating a Gene with Hair Follicle Formation-Inducing Ability
It is intended to provide a method of regenerating follicles which comprises inhibiting the expression of one or more genes capable of inhibiting follicle formation that are selected from the group...
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US20080089872 |
Method for purifying pluri-differentiated mesenchymal progenitor cells
There is provided an isolated pluri-differentiated human mesenchymal progenitor cells (MPCs), a method for isolating and purifying human mesenchymal progenitor cells from Dexter-type cultures, and...
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US20080089871 |
Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells
Compositions and methods are provided for treatment of cartilage defects in animals and humans. The compositions of the invention include synovial tissue, synovial cells and matrices containing...
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US20080089870 |
Cultured Melanocytes on Bioploymer Membranes for Treatment of Hyper and Hypopigmentation Disorders
The present invention relates to a graft wherein cultured autologous melanocytes are delivered using a biopolymer. The present invention describes the composition, method of preparation and its...
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US20080089869 |
PROAEROLYSIN CONTAINING PROTEASE ACTIVATION SEQUENCES AND METHODS OF USE FOR TREATMENT OF PROSTATE CANCER
Disclosed herein are modified proaerolysin (PA) peptide. In some examples, the proteins include a prostate-specific protease cleavage site and can further include a prostate-tissue-specific binding...
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US20080089868 |
Retinal stem cell compositions and methods for preparing and using same
Provided are cell compositions including non-retinal cell types that have been reprogrammed to form retinal stem cells, and methods for producing and using same. Such reprogrammed cells can be used...
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US20080085264 |
METHODS FOR ENHANCING STEM CELL ENGRAFTMENT DURING TRANSPLANTATION
The present invention relates to the fields of hematopoietic stem cell transplantation and molecular biology. More specifically, methods for improving engraftment efficiency in stem cell...
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US20080081033 |
PREPARATION OF A CELL CONCENTRATE FROM A PHYSIOLOGICAL SOLUTION
The present invention is directed to methods and compositions regarding the preparation of an cell concentrate, such as, for example, an osteogenic cell concentrate, from a physiological solution,...
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US20080075751 |
Method for IN VIVO, EX VIVO and IN VITRO rapair and regeneration of cartilage and collagen and bone remodeling
A method for in vivo, ex vivo and in vitro regeneration of cartilage and collagen. In vivo, ex vivo and in vitro regeneration and de novo formation of articular cartilage and collagen by...
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US20080075750 |
METHODS FOR PRODUCING THREE-DIMENSIONAL TISSUE-ENGINEERED CARDIAC CONSTRUCTS AND USES REGARDING SAME
The invention relates generally to methods for producing a three-dimensional (3D) tissue-engineered cardiac construct and more specifically, a vascularized 3D tissue-engineered cardiac construct...
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US20080075705 |
Method for increasing tumor cell immunogenicity using heat shock protein
A method for induction of endogenous heat shock protein in tumor cells using a simple heat shock treatment which provides a simple and inexpensive method for augmenting antitumor vaccine potency....
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US20080075700 |
Method and composition for treating diabetes
The present invention is directed to the expansion, preferably TVEMF-expansion, of mammalian blood stem cells in a rotating bioreactor, preferably a TVEMF-bioreactor, to compositions resulting from...
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US20080075699 |
METHOD FOR ISOLATING AND/OR IDENTIFYING MESENCHYMAL STEM CELLS (MSC)
The present invention concerns antibodies produced from hybridoma cell lines chosen from the group comprising W8B2, W1C3, W7C6, W5C4, 24D2, 28D4, HEK-3D6, W4A5, W3D5, W5C5, 9A3G9, 58B1, F9-3C2F1,...
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US20080075698 |
Brain-Localizing Bone Marrow Progenitor cells
The present inventors discovered that brain-localizing cells exist in the progenitor cell fraction of bone marrow cells. They also elucidated various characteristics of the brain-localizing cells....
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US20080069890 |
Method for treating patients with implants of islets which have been kept in long term, in vitro culture
The invention relates to the use of macrobeads which have been kept in in vitro storage for long term culture, i.e., for at least about 8 months. The macrobeads surprisingly exhibit continued...
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US20080057100 |
Implantable device for delivery of therapeutic agents
A percutaneously implantable device for the treatment of a cardiac condition or other disease is disclosed herein, the device capable of delivery and maintenance of a therapeutic scaffold. A...
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US20080057095 |
Bone semi-permeable device
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
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US20080057069 |
Method of increasing trafficking of endothelial progenitor cells to ischemia-damaged tissue
This invention provides a method of increasing trafficking of endothelial progenitor cells to ischemia-damaged tissue in a subject comprising administering to the subject an agent that inhibits...
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US20080057043 |
Monocyte cell
A human monocyte cell characterised by the expression of the following markers: Tie2, CD16 and CD14.
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US20080057042 |
METHOD OF PROVIDING READILY AVAILABLE CELLULAR MATERIAL DERIVED FROM CORD BLOOD, AND A COMPOSITION THEREOF
The present invention is directed to the TVEMF-expansion of mammalian cord blood stem cells in a rotating TVEMF-bioreactor, to compositions resulting from the TVEMF-expanded cells, and to a method...
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US20080057041 |
Derivation of embryonic stem cells and embryo-derived cells
This present invention provides novel methods for deriving embryonic stem cells and embryo-derived cells from an embryo without requiring destruction of the embryo. The invention further provides...
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US20080057040 |
Cell Preservation Method
The present invention provides a method for freezing a stem cell or a cell derived therefrom, the method including the steps of providing a cell suspension, performing ice nucleation on the cell...
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US20080050417 |
ALGINATE COATED, COLLAGEN MATRIX CELLULAR DEVICE, PREPARATIVE METHODS, AND USES THEREOF
The present invention is directed to cellular devices comprising a collagen matrix, cell layer, and gelled alginate layer, processes for producing the devices, methods of implanting the devices,...
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US20080050349 |
CELL BASED THERAPY FOR THE PULMONARY SYSTEM
Cell based therapy comprises administration to the lung by injection into the blood system of viable, mammalian cells effective for alleviating or inhibiting pulmonary disorders. The cells may...
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US20080050348 |
Method and composition for repairing heart tissue
A method of expanding blood stem cells for the repair of heart tissue and/or function, and compositions resulting from the expansion method in a rotating bioreactor. This invention also relates to...
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US20080050347 |
STEM CELL THERAPY FOR CARDIAC VALVULAR DYSFUNCTION
Disclosed are methods, compounds and compositions useful for treatment of a patient with valvular dysfunction. The invention relates to using stem cells, modified stem cells, derivatives thereof,...
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US20080050346 |
Elastin producing fibroblast formulations and methods of using the same
The present invention describes therapeutic compositions comprising fibroblasts that have been stimulated to increase expression of extracellular matrix components or elastin, or to produce...
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US20080044448 |
Bone semi-permeable device
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
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