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US20150140058 SKIN PRINTING AND AUTO-GRAFTING  
A holey substrate now is used for constructing a graft product, such as building an auto-graft by 3D printing of living cells. When the autograft built atop the holey substrate is implanted, blood...
US20110002904 SYNOVIAL VILLI FOR USE WITH TISSUE ENGINEERING  
Synovial villi derived explants and related surgical tools used to repair or prevent damage to injured or diseased tissue, including connective tissue. The tools including a harvesting tool for...
US20150139960 SKIN PRINTING AND AUTO-GRAFTING  
An apparatus and method for the production of substitute skin that advantageously reduces the amount of donor dermal cells needed from non-wound areas of a patient having a wound to be...
US20120276154 CREATION OF HAIR FOLLICLES IN TISSUE-ENGINEERED SKIN GRAFTS  
A living tissue-engineered skin graft having a potential to develop hair follicles includes a multilayered skin-like structure of alternating nanofiber mats and layers of fibroblasts assembled in...
US20110159051 Composite for Thermo-Sensitive Cell-Tissue Transplanted Scaffold and Use thereof  
A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can...
US20130195958 PROCESS FOR THE PRODUCTION OF PATCHES OR DERSSINGS OF AUTOLOGOUS SKIN THROUGH CULTIVATION OF AUTOLOGOUS KERATINOCYTES AND FIBROBLASTS WITH AUTOLOGOUS SERUM FOR THE GENERATION OF SKIN  
The process in general is based on taking a sample of skin and a sample of blood from the patient and based on these two elements skin is cultured, being placed on a collagen patch to produce a...
US20130216601 THREE-DIMENSIONAL BONE IMPLANT AND METHOD FOR PRODUCING SAME  
A method for ex vivo production of a three-dimensional bone implant adapted for implantation to a patient, implants produced by such a method, and uses of such implants. The method comprises...
US20150104432 COMPLETE HUMAN SKIN ORGAN GENERATED FROM CULTURE-EXPANDED CELLS  
Systems and methods can support generation of a full-thickness, human skin organ from tissue culture expanded cells. Human dermal and epidermal progenitor cells can be isolated from human tissues....
US20110212162 LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS  
Disclosed herein are compositions and methods for and involving selectively targeting tumor lymphatics.
US20140322672 ROOT CANAL FILLING MATERIAL CONTAINING MESENCHYMAL STEM CELLS AND METHOD FOR REGENERATING DENTAL TISSUE USING THE SAME  
A root canal filling material for a tooth extraction or tooth non-extraction process can be used clinically because of its easy availability and can efficiently enhance dental tissue regeneration;...
US20110110898 Bioactive removal of hypertrophic scars  
An embodiment of the invention includes methods for the long-term augmentation and/or repair of skin defects (scars, skin laxness, skin thinning, and skin augmentation), cellulite, breast tissue,...
US20120064049 USE OF STEM CELLS FROM HAIR ROOT SHEATHS AND KERATINOCYTE PRECURSOR CELLS FOR THE REGENERATION OF AGED SKIN  
The present invention relates to the use of stem cells from hair root sheaths and/or keratinocyte precursor cells for the regeneration of aged but otherwise healthy and non-injured skin for the...
US20150125429 GENE TARGETING METHODS AND TOOLS  
Provided herein is a general method of correcting a gene, for example a gene with many known mutations, such as a gene with mutations in many different exons which could vary from subject to...
US20120282300 PROTEIN BIOMATERIALS AND BIOCOACERVATES AND METHODS OF MAKING AND USING THEREOF  
The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention...
US20110212157 DERMAL DELIVERY  
The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis,...
US20130078222 Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof  
Provided are intervertebral disk nucleus pulposus stem cells or progenitor cells that may be used for treatment of intervertebral disk disorders. An intervertebral disk nucleus pulposus cell is...
US20100330046 HUMAN SKIN SUBSTITUTES EXPRESSING IL-12  
The present invention relates generally to compositions for treating patients that have skin cancer or have recently had skin cancers removed. More specifically, the present invention provides...
US20150246157 SCAFFOLD FOR CARDIAC PATCH  
A biocompatible and biodegradable medical device patch actuating primarily as soft tissue structural reinforcement. The device has a layered architecture, where the primary serves as suturing...
US20140341864 METHODS FOR PRODUCING RETINAL TISSUE AND RETINA-RELATED CELL  
The invention provides a method for producing a retinal tissue by (1) subjecting pluripotent stem cells to floating culture in a serum-free medium containing a substance inhibiting the Wnt signal...
US20100310627 Xenotransplant for Stroke Therapy  
Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.
US20130330301 Enhanced Medical Implant  
A medical implant comprising in components from a tooth and stem cells harvested from at least one tooth. Pluripotent stem cells, other cells, and biologic constituents of the dental pulp may be...
US20130309208 Enhanced Medical Implant  
A medical implant comprising in components from a tooth and stem cells harvested from at least one tooth. Pluripotent stem cells, other cells, and biologic constituents of the dental pulp may be...
US20110020310 ROOT CANAL FILLER AND DENTAL TISSUE REGENERATION METHOD  
Provided is a novel and creative dental tissue regeneration method for regenerating dental tissue after pulpectomy or the enlargement and cleaning of an infected root canal. After pulpectomy or...
US20130029292 METHOD OF IMPLANTING MESENCHYMAL STEM CELLS FOR NATURAL TOOTH REGENERATION IN SURGICALLY PREPARED EXTRACTION SOCKET AND COMPOSITIONS THEREOF  
The present invention provides a method and compositions for tooth regeneration. Both implants of adipose-derived stem cell and dental pulp stem cell are able to grow self-assembled new teeth in...
US20150165091 CONTROLLING EXTRACELLULAR MATRIX PROTEIN MICROSTRUCTURE WITH ULTRASOUND  
The present invention is directed to methods of controlling extracellular matrix protein microstructure in a biological composition using ultrasound technology. The invention is further directed...
US20150010509 CALCIUM FOLATE (CAFOLATE) AND THERAPEUTIC METHODS BASED THEREON  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection, tuberculosis and type 2 diabetes based upon the...
US20130142835 SYNTHETIC SCAFFOLDS AND ORGAN AND TISSUE TRANSPLANTATION  
Articles, compositions, and methods for growing tissues and organs using bioreactors, including rotating bioreactors, are provided. Synthetic scaffolds for growing artificial tissue and organ...
US20120251495 PTERIN BASED THERAPIES FOR INFLAMMATORY CONDITIONS  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection based upon the administration of calcium pterin. In one...
US20140377235 METHODS FOR USING SYNTHETIC TRITERPENOIDS IN THE TREATMENT OF BONE OR CARTILAGE DISEASES OR CONDITIONS  
The present invention features the use of a synthetic triterpenoid to induce gene expression and differentiation of stem or progenitor cells in the treatment of bone/cartilage diseases or conditions.
US20130089526 Methods for Using Synthetic Triterpenoids in the Treatment of Bone or Cartilage Diseases or Conditions  
The present invention features the use of a synthetic triterpenoid to induce gene expression and differentiation of stem or progenitor cells in the treatment of bone/cartilage diseases or conditions.
US20120183509 MICROGLIAL PRECURSOR CELLS FOR THE TREATMENT OF MALIGNANT NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM  
Microglial precursor cells for use in the treatment of malignant neoplasms of the central nervous system. A method of treating malignant neoplasms of the central nervous system comprising...
US20110257726 SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION  
Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The...
US20140178343 SUPPORTS AND METHODS FOR PROMOTING INTEGRATION OF CARTILAGE TISSUE EXPLANTS  
The present disclosure provides tissue supports and methods for preparing a cartilage composition for repairing cartilage defects, which is prepared by expanding and integrating small cartilage...
US20120015003 Layered Scaffold Suitable for Osteochondral Repair  
The invention relates to a method for producing a multi-layer collagen scaffold. The method generally comprises the steps of: preparing a first suspension of collagen and freezing or lyophilising...
US20120237488 LSC AND HSC SIGNATURES FOR PREDICTING SURVIVAL OF PATIENTS HAVING HEMATOLOGICAL CANCER  
A method for determining prognosis in a subject having a hematological cancer comprising: a) determining an expression profile by measuring the gene expression levels of a set of genes selected...
US20130022661 BIO-REMODABLE BONE AUGMENTATION DEVICE AND METHOD  
A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having...
US20100310526 COSMETIC METHOD FOR INCREASING THE PIGMENTATION OF SKIN USING MELANOCYTE PRECURSOR CELLS  
The present invention proposes a cosmetic method for increasing the pigmentation of skin with the steps application of melanocyte precursor cells from root sheaths collected from a first area of...
US20130202568 Ameliorating Nervous Systems Disorders  
The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic...
US20110165129 Ameliorating Nervous Systems Disorders  
The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic...
US20130243737 CALCIUM-CONTAINING STRUCTURES AND METHODS OF MAKING AND USING THE SAME  
The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in...
US20120201786 METHODS FOR THE USE OF STEM CELLS AND STEM CELL FACTORS IN THE TREATMENT OF SKIN CONDITIONS  
The invention provides a method for treating a skin condition in a patient through the administration of stem cells, stem cell factors or a combination thereof. The invention finds use in medical...
US20140099290 ENDOTHELIAL SCAFFOLDS  
Provided herein is an endothelial scaffold comprising, consisting of, or consisting essentially of decellularized corneal stroma. In some embodiments, the scaffold has cultured endothelial cells...
US20110165130 Methods for Preparing Human Skin Substitutes from Human Pluripotent Stem Cells  
The present invention relates to an ex vivo method for obtaining a population of human keratinocytes derived from human pluripotent stem cells comprising a step of co-culturing human pluripotent...
US20110282239 Tissue Harvesting Device with Manual Dicing Mechanism  
A dicing device dices tissue harvested from a patient. The dicing device comprises a grid cutting element and a tray to receive diced tissue. The dicing device may be integrated into an otherwise...
US20130259839 GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF TISSUE OF ORIGIN OF TUMOR SAMPLES  
The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules...
US20110076316 SCALABLE MATRIX FOR THE IN VIVO CULTIVATION OF BONE AND CARTILAGE  
The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue...
US20110177041 MATERIAL FOR TREATMENT OF CEREBRAL INFARCTION AND BRAIN TISSUE REGENERATION METHOD  
Disclosed is a therapeutic material for cerebral infarction, which can recover a vascular disorder in an area affected by cerebral infarction to improve the brain function. The therapeutic...
US20100303880 Tissue scaffolding comprising surface folds for tissue engineering  
The invention is directed to solid gradient scaffolds, methods of producing the same, and therapeutic applications arising from their utilization. Specifically, the gradient scaffolding includes,...
US20150159134 METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIAL CELLS  
The invention relates to a method for producing retinal pigment epithelial cells.
US20130259910 METHOD FOR USE OF A DOUBLE-STRUCTURED TISSUE IMPLANT FOR TREATMENT OF TISSUE DEFECTS  
A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary...