|
Match
|
Document |
Document Title |
|
|
US20110286932 |
OPTICAL METHOD FOR THE DETECTION OF ALZHEIMER'S DISEASE
The present subject matter relates to a non-invasive optical imaging method for monitoring early pathological events specific to Alzheimer's disease (AD), such as the development, amount and...
|
|
|
US20110311442 |
DIRECT CELLULAR ENERGY DELIVERY SYSTEM
A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group...
|
|
|
US20120014868 |
METHODS TO DIAGNOSE DEGENERATIVE DISC DISEASE
Methods are provided that better describe, and localize the pain generator or suspected pain generator in and around spinal discs in relation to neck or back pain so as to improve the diagnosis of...
|
|
|
US20110286937 |
SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
|
|
|
US20120128594 |
SELECTIVE INFARCTED-TISSUE-TARGETING BACTERIA AND USE THEREOF
The present invention relates to bacteria which specifically target infracted tissue and use thereof. The present invention provides a selective infracted tissue-targeting bacterium for the first...
|
|
|
US20110206615 |
PROBE REAGENT FOR MEASURING OXIDATIVE STRESS
The present invention relates to fluorescent or luminescent probe reagents for measuring oxidative stress in a cell or an organism. Examples of the probe reagents include: a fluorescent or...
|
|
|
US20110077512 |
Biopsy marker composition and method of use
An aqueous suspension of titanium dioxide, polymethylmethacrylate and Vitamin E oil is used to mark a location wherein a skin biopsy has been taken to enable subsequent identification of the biopsy...
|
|
|
US20120207683 |
EVALUATION PROBE FOR CENTRAL NERVOUS SYSTEM PERMEABILITY, EVALUATION METHOD FOR CENTRAL NERVOUS SYSTEM PERMEABILITY, AND SCREENING METHOD USING AN EVALUATION PROBE FOR CENTRAL NERVOUS SYSTEM PERMEABILITY
Provided is an evaluation probe capable of optically evaluating permeability of a substance through a central nervous system tissue. Also provided is an evaluation method for permeability of a...
|
|
|
US20130129614 |
Microorganisms for imaging and/or treatment of tumors
Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in...
|
|
|
US20120244068 |
Microorganisms for imaging and/or treatment of tumors
Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in...
|
|
|
US20130129616 |
GEL COMPOSITION FOR FILLING A BREAST MILK DUCT PRIOR TO SURGICAL EXCISION OF THE DUCT OR OTHER BREAST TISSUE
The invention is a gel composition for delivery to a breast milk duct prior to surgical excision of breast tissue including cancerous lesions. The invention also provides methods of mapping all or...
|
|
|
US20110293527 |
Modified vaccinia virus strains for use in diagnostic and therapeutic methods
Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as...
|
|
|
US20120156131 |
DIAGNOSIS AND TREATMENT OF TUMORS
The present invention is directed to methods and compositions for the treatment and diagnosis of neuroectodermally-derived tumors, such as gliomas. The inventive methods of treatment generally...
|
|
|
US20120230918 |
NON-INVASIVE IN VIVO OPTICAL IMAGING METHOD
The present invention relates to a non-invasive method of determining the presence, quantifying the blood level, and/or monitoring or determining the blood clearance of a fluorescent analyte which...
|
|
|
US20100329989 |
In Vivo Labeling of Mammalian Cone Photoreceptors by Intravitreal Injection of Fluorescently Tagged Peanut Agglutinin
A method for specifically labeling of mammalian cone photoreceptors in vivo comprising injecting a mammal with peanut agglutinin conjugated with a fluorescent probe. The peanut agglutinin labels...
|
|
|
US20120076735 |
Nanoparticles for Extravascular Administration
Disclosed are drug delivery systems and methods for extravascular administration of drug, vaccine, and/or diagnostic agents, for use in research and medical applications.
|
|
|
US20110195029 |
FLUORESCENT EMULSION
The invention relates to a fluorescent emulsion, to its uses and to labelling reagents comprising it. The fluorescent emulsion of the invention is of the oil-in-water type, comprising at least one...
|
|
|
US20100329990 |
LUMINESCENT MARKERS
The invention relates to luminescent proteins, nucleic acids encoding same, compositions and combinations comprising the proteins, and methods using the proteins, nucleic acids, compositions and...
|
|
|
US20110223109 |
DIAGNOSTIC SUBSTANCE FOR USE IN A METHOD FOR DETERMINING THE AGGRESSIVENESS OF A PROSTATE TUMOR AND DIAGNOSTIC METHOD
In order to determine the aggressiveness of a prostate tumor, a diagnostic substance is administered to a patient that includes a biomarker provided with a first label that is detectable with a...
|
|
|
US20120052003 |
MICROORGANISMS FOR PREVENTING AND TREATING NEOPLASMS ACCOMPANYING CELLULAR THERAPY
Provided are methods for using cellular compositions in combination with oncolytic viruses. The methods include administering oncolytic viruses for the inhibition and treatment of tumors caused by...
|
|
|
US20110064650 |
MICROORGANISMS FOR PREVENTING AND TREATING NEOPLASMS ACCOMPANYING CELLULAR THERAPY
Provided are methods for using cellular compositions in combination with oncolytic viruses. The methods include administering oncolytic viruses for the inhibition and treatment of tumors caused by...
|
|
|
US20110177003 |
PROTEINS THAT FLUORESCE AT INFRARED WAVELENGTHS OR GENERATE SINGLET OXYGEN UPON ILLUMINATION
This invention provides novel truncation mutants of a phytochrome from the bacterium Deinococcus radiodurans. When expressed either in bacteria or mammalian cells, these mutant phytochromes...
|
|
|
US20120093722 |
SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active...
|
|
|
US20130121924 |
FLUORESCENCE DETECTION OF POISON OAK OIL
The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to...
|
|
|
US20120093718 |
LIPOSOMAL NANOPARTICLES AND OTHER FORMULATIONS OF FENRETINIDE FOR USE IN THERAPY AND DRUG DELIVERY
Formulations of neutral retinoids, in particular fenretinide (HPR) in the form of lipid nanoparticles, solid dipersions and emulsions are disclosed. These compositions are used to treat diseases...
|
|
|
US20110195019 |
NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 251P5G2 USEFUL IN TREATMENT AND DETECTION OF CANCER
A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
|
|
|
US20110236310 |
LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD
The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as...
|
|
|
US20110280810 |
SURGICAL OPTICAL SYSTEMS FOR DETECTING BRAIN TUMORS
A method of detecting a brain tumor includes administering indocyanine green to a living body; exposing brain tissue in the living body; irradiating the exposed brain tissue with excitation light...
|
|
|
US20100303729 |
CYANOCHROME FLUOROPHORES
Genetically-engineered cyanochrome fluorophore molecules (fluorophores) with increased fluorescence and with absorbing fluorescence in the blue and green (blue/green) portion of the light spectrum...
|
|
|
US20120087859 |
NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES
The present invention relates to a biopolymer-modified nanocarrier in which chitosan is bound to a water-soluble biocompatible polymer that has been crosslinked via a photo-crosslinkable functional...
|
|
|
US20120128585 |
Method of Diagnosing the presence of a tumor in a mammal by assessing CDO expression level
The present invention provides for a method of using BOC/CDO hedgehog antagonists to inhibit hedgehog signaling, as well as treating and diagnosing disorders relating to hedgehog signaling or...
|
|
|
US20120282172 |
TARGETED DELIVERY TO HUMAN DISEASES AND DISORDERS
The present invention provides a system presenting site-specific accumulation through a ligand that specifically targets a receptor overexpressed on the surface of specific cells within a target...
|
|
|
US20120101390 |
Multi-Modal Imaging for Diagnosis of Early Stage Epithelial Cancers
Epithelial cancer screening can include a staining tissue with a cancer targeting agent, identifying a potentially cancerous lesion using fluorescence imaging, and imaging the potentially cancerous...
|
|
|
US20120121505 |
THERAPEUTIC COMPOSITIONS AND METHODS
The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.
|
|
|
US20110206617 |
MODIFIED POLYSACCHARIDES FOR DRUG AND CONTRAST AGENT DELIVERY
According to one embodiment, the disclosure provides a delivery formulation including a chitosan in which the primary amines are partially modified with 4-imidazole acetic acid monohydrochloride...
|
|
|
US20110200532 |
Fluorescent emulsion of indocyanine green
The present invention relates to a formulation of indocyanine green in the form of a nanoemulsion, comprising a continuous aqueous phase and at least one dispersed oily phase, in which the oily...
|
|
|
US20110305641 |
Compositions And Methods For Treatment Of Angiogenesis-Associated Ocular Disorders
The invention provides methods and compositions for identifying and quantifying pathological changes on the retina.
|
|
|
US20120107229 |
NOVEL NANO-PROBES FOR MOLECULAR IMAGING AND TARGETED THERAPY OF DISEASES
The present inventions relate to compositions and methods for imaging and treating atherosclerotic diseases, pathogen infections, and tumors by administering actively targeting magnetic...
|
|
|
US20120087860 |
METHODS FOR IN VIVO CANCER DETECTION, DIAGNOSIS AND THERAPY USING MULTIDOMAIN BIOTAGS
In another embodiment, a method for detecting and/or diagnosing a cancer in a subject is provided. The method may include administering an effective dose of a biotag to a subject, or alternatively,...
|
|
|
US20110081293 |
METHODS AND COMPOSITIONS RELATED TO CLOT-BINDING LIPID COMPOUNDS
Disclosed are compositions and methods related to clot-binding head groups. The disclosed targeting is useful for treatment of cancer and other diseases and disorders.
|
|
|
US20110286922 |
IMAGING AND RADIOTHERAPY METHODS
The present invention relates to in vivo imaging and radiotherapeutic methods and agents which target the enzyme aldehyde dehydrogenase (ALDH) and that are suitable for the in vivo imaging of...
|
|
|
US20130129632 |
Quantum dot materials, methods for making them, and uses thereof
The disclosure provides quantum dot materials, compositions and methods useful in the treatment of various disorders. In particular, the disclosure provides cadmium-free and lead-free quantum dots.
|
|
|
US20120107244 |
MONOMERIC VARIANTS OF THE TETRAMERIC eqFP611
Monomeric eqFP611 variants exhibit red fluorescent properties and DNA encoding monomeric eqFP611 variants.
|
|
|
US20130028837 |
CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
|
|
|
US20120276006 |
CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
|
|
|
US20130129619 |
Molecular Imaging of Cancer Cells In Vivo
Cellular targets on cancer cells have been identified that can be used with targeted molecular imaging to detect the cancer cells in vivo. Non-invasive methods for detecting cancer cells, such as...
|
|
|
US20120039803 |
PRETARGETING KIT, METHOD AND AGENTS USED THEREIN
Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal...
|
|
|
US20120144506 |
DOUBLE-FUSION HUMAN EMBRYONIC STEM CELLS, METHOD OF MAKING DOUBLE-FUSION HUMAN EMBRYONIC STEM CELLS, TRIPLE-FUSION HUMAN EMBRYONIC STEM CELLS, METHOD OF MAKING TRIPLE-FUSION HUMAN EMBRYONIC STEM CELLS, AND METHODS OF MONITORING DOUBLE-FUSION HUMAN EMBRYONIC STEM CELLS AND TRIPLE-FUSION HUMAN EMBRYONIC STEM CELLS
Embodiments of the present disclosure include double-fusion human embryonic stem cells, methods of imaging double-fusion human embryonic stem cells, double-fusion polynucleotides, double-fusion...
|
|
|
US20120225019 |
Dual Fluorescence Assay For Determining Viability Of Parasitic Or Non-Parasitic Worms
A two colour fluorescent assay and a kit are described that permit the determination of live and dead parasitic or non-parasitic worms, for example helminths. The assay permits screening for the...
|
|
|
US20110020239 |
METHODS FOR IN VIVO IMAGING OF CELLS
The instant invention provides methods for the in vivo imaging of cells using one or more imaging modalities.
|