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US20150071992 CONCENTRATED, INHALABLE ANTIBIOTIC FORMULATION  
A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The...
US20110014247 METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS  
This invention provides compositions that include a protein and at least two protease inhibitors, method for treating diabetes mellitus, and methods for administering same, and methods for oral...
US20110142800 METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS  
This invention provides compositions comprising a protein, an absorption enhancer, a protease inhibitor, methods for treating diabetes mellitus, comprising administering same, and methods for oral...
US20100310511 DETERMINING DISEASE OR IMMUNE SYSTEM FEATURES BASED ON ANALYSIS OF IMMUNE SYSTEM CHARACTERISTICS  
Methods for analyzing one or more elements, markers, ligands or other characteristics of the immune system of a body (e.g., of a human or other animal), and based on the analysis, determine a...
US20130129670 MACROPHAGE ACTIVATING FACTOR FOR USE IN THE TREATMENT OF CHRONIC FATIGUE SYNDROME (CFS) AND CFS-RELATED DISEASES AND DISORDERS  
The present invention relates to Macrophage Activating Factors such as GcMAF and compositions thereof, for use in the treatment of a patient suffering from CFS/ME and/or XMRV infection.
US20100310469 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS  
A method of immunotherapy to treat cancer or a synergistic anti-cancer treatment by administering an effective amount of natural cytokine mixture (NCM), an effective amount of cyclophosphamide...
US20120100102 CANCER VACCINE  
We disclose a vaccine comprising a pappalysin and vaccine compositions comprising a pappalysin.
US20130195794 CANCER VACCINE  
The disclosure relates to a vaccine including at least one adjuvant useful in the prevention and treatment of blood cancers, for example lymphoma, leukaemia or myeloma.
US20120225029 Skin Cream  
The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising cell culture medium conditioned by cells...
US20140377221 BIOMARKERS AND COMBINATION THERAPIES USING ONCOLYTIC VIRUS AND IMMUNOMODULATION  
The invention disclosed herein describes biomarkers useful for prognosis, selection and monitoring of oncolytic virus therapy for patients with various types of cancer. In particular, the present...
US20130295043 VACCINATION IN ELDERLY PATIENTS  
The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in an elderly patient preferably exhibiting an age of at...
US20110250171 Compositions and Methods for Cancer Immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
US20120076837 SURFACE ENGINEERING OF TISSUE GRAFT MATERIALS FOR ENHANCED POROSITY AND CELL ADHESION  
In one aspect, the invention relates to providing enhanced application tissue graft materials in regenerative medicine through improved cellular interactions. Biocompatible implant materials,...
US20120213734 Method for Cancer Therapy Based on a Co-Administration of a Parvovirus and a Cytokine  
Described is a pharmaceutical composition comprising (a) a parvovirus and (b) a cytokine, preferably IFN-γ, and the use of said composition for treatment of cancer, e.g., a brain tumor.
US20140147414 COMPOSITIONS AND METHODS FOR TREATMENT OF INTRACELLULAR DAMAGE  
Pre-implantation factor (PIF) may be used to treat intracellular damage. Aspects of the invention are directed to a method of treating intracellular damage comprising administering PIF to a...
US20150174212 IDENTIFYING AND MODULATING MOLECULAR PATHWAYS THAT MEDIATE NERVOUS SYSTEM PLASTICITY  
The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in...
US20110002881 TREATMENT AND PROPHYLAXIS  
This invention discloses the use of an E-selectin antagonist in methods and compositions for treating or preventing immunocompromised conditions resulting from medical treatment. The present...
US20110033419 Methods and Compositions for Treating Cancer  
The invention relates to a method of treating cancer, comprising administering to a subject in need thereof an effective amount of a HSV-2 virus, wherein the virus lacks protein kinase activity of...
US20140348788 METHOD TO MODULATE PIGMENTATION PROCESS IN THE MELANOCYTES OF SKIN  
The invention describes a method to modulate melanosome maturation process in melanocytes. Further, it describes a method to reversibly alter the process of pigmentation in the human epidermal...
US20120251439 Antigens Associated with Inflammatory Bowel Disease Including Ulcerative Colitis  
Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of inflammatory bowel disease such as ulcerative colitis...
US20140065102 METHODS FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D INFECTIONS  
It is disclosed a method for the treatment of HBV infection or HBV/HDV co-infection, the method comprising administering to a subject in need of treatment a first pharmaceutically acceptable agent...
US20100310504 METHODS FOR TREATING FIBROSIS BY MODULATING CELLULAR SENESCENCE  
Fibrosis arises as part of a wound healing response that maintains organ integrity following catastrophic tissue damage, but can also contribute to a variety of human pathologies, including liver...
US20140369963 METHODS FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D INFECTIONS  
It is disclosed a method for the treatment of hepatitis B (HBV) infection or HBV/hepatitis D (HDV) co-infection, the method comprising administering to a subject in need of treatment a first...
US20140369962 METHODS FOR THE TREATMENT OF HEPATITIS B AND HEPATITIS D INFECTIONS  
It is disclosed a method for the treatment of hepatitis B (HBV) infection or HBV/hepatitis D (HDV) co-infection, the method comprising administering to a subject in need of treatment a first...
US20110165121 USE OF PEGYLATED TYPE III INTERFERONS FOR THE TREATMENT OF HEPATITIS C  
Methods for treating human patients infected with the hepatitis C virus using pegylated Type III Interferons (IL-28A, IL-28B and IL-29) alone or in combination with other antiviral agents.
US20110135596 FUSION PROTEIN COMPRISING UBIQUITIN OR UBIQUITIN-LIKE PROTEIN, MEMBRANE TRANSLOCATION SEQUENCE AND BIOLOGICALLY ACTIVE MOLECULE AND USE THEREOF  
A transmembrane fusion protein including ubiquitin or a ubiquitin-like protein, a membrane translocation sequence linked to the C-terminus of the ubiquitin or ubiquitin-like protein, and a...
US20130121958 STREPTAVIDIN AND BIOTIN-BASED ANTIGEN DELIVERY SYSTEM  
The present invention provides an innovative versatile system, which allows delivery of one or several antigens or biologically active molecules into or onto targeted subset of cells. The...
US20150174100 METHODS FOR THE TREATMENT OF PSORIATIC ARTHRITIS USING APREMILAST  
Methods of treating, managing or preventing psoriatic arthritis are disclosed. Specific methods encompass the administration of apremilast, alone or in combination with a second active agent.
US20140301980 METHODS FOR THE TREATMENT OF PSORIATIC ARTHRITIS USING APREMILAST  
Methods of treating, managing or preventing psoriatic arthritis are disclosed. Specific methods encompass the administration of apremilast, alone or in combination with a second active agent.
US20110091421 Methods of Novel Therapeutic Candidate Identification Through Gene Expression Analysis in Vascular-Related Diseases  
The present invention discloses multiple treatment regimens for vascular-related diseases and disorders. The present invention provides for methods of treating vascular-related disorders based on...
US20120087859 NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES  
The present invention relates to a biopolymer-modified nanocarrier in which chitosan is bound to a water-soluble biocompatible polymer that has been crosslinked via a photo-crosslinkable...
US20110020270 TREATMENT AND PROPHYLAXIS  
This invention discloses the use of an E-selectin antagonist and a mobilizer of hematopoietic stem cells or progenitor cells in methods and compositions for treating or preventing...
US20140242142 CELL SECRETED PROTEINS FOR THE TREATMENT OF MYOCARDIAL INFARCTION  
The present invention relates to the use of secreted proteins from mesenchymal stem cells and other cells for the treatment of myocardial infarction. In particular, the invention provides...
US20140294761 TREATMENTS FOR MIGRAINE AND RELATED DISORDERS  
Embodiments are directed to compositions and methods of treating migraine and related neurological disorders. In certain aspects, methods and compositions are for reducing cortical spreading...
US20140369955 METHODS FOR AUTOLOGOUS STEM CELL TRANSPLANTATION  
Materials and methods for obtaining populations of lymphocytes and administering the population of lymphocytes to a subject are disclosed herein. In particular, disclosed herein are materials and...
US20100151009 FORMULATIONS FOR DELIVERING INSULIN  
Oral insulin formulations and processes for preparing oral insulin formulations are provided.
US20130129678 CO-ADMINISTRATION OF A PARVOVIRUS AND A CYTOKINE FOR THERAPY OF PANCREATIC CANCER  
The application relates to a combination of a parvovirus and a cytokine, preferably IFNγ, for use in treating pancreatic cancer (PDAC), in particular a terminal stage of this disease.
US20140369957 COMBINATION OF GROWTH FACTORS, CYTOKINES, ANTIBACTERIAL/ANTIVIRAL FACTORS, STEM CELL STIMULATING FACTORS, COMPLEMENT PROTEINS C3A/C4A, IMMUNOGLOBULINS AND CHEMOTACTIC FACTORS  
The present invention refers to a combination of growth factors, cytokines, antibacterial/antiviral factors, stem cell stimulating factors, complement proteins C3a/C4a, immunoglobulins and...
US20130101553 INDUCING INACTIVATION OF FIBROGENIC MYOFIBROBLASTS  
Provided are methods of treating fibrotic conditions in a subject and diagnostic methods for determining fibrosis and appropriate treatments for the fibrosis by the identification of specific...
US20130028861 CYTOKINES FOR THE TREATMENT OF ADDICTIONS  
The present invention relates to a cytokine for use in the treatment and/or control of dependent and/or addictive behavior, in particular addiction and/or dependency to nicotine, food addiction,...
US20140154209 POLYMORPHISMS ASSOCIATED WITH NON-RESPONSE TO A HEPATITIS C TREATMENT OR SUSCEPTIBILITY TO NON-SPONTANEOUS HEPATITIS C CLEARANCE  
The present invention relates to in vitro methods of determining a susceptibility to non-response to a hepatitis C treatment or a susceptibility to non spontaneous hepatitis C clearance in a...
US20130224144 SEQUENTIAL ADMINISTRATION OF A REPLICATION DEFECTIVE ADENOVIRUS VECTOR IN VACCINATION PROTOCOLS  
Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to...
US20130230486 COMPOSITIONS AND METHODS TO INDUCE TARGETED APOPTOSIS  
Embodiments herein concern compositions and methods for treating a subject having or suspected of developing a pulmonary disorder or cancer. Certain embodiments concern modulating protein tyrosine...
US20120148528 COMPOSITIONS AND METHODS TO INDUCE TARGETED APOPTOSIS  
Embodiments herein concern compositions and methods for treating a subject having or suspected of developing a pulmonary disorder or cancer. Certain embodiments concern modulating protein tyrosine...
US20150079034 COMPOSITIONS COMPRISING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF  
The present invention provides recombinant Listeria strains comprising an angiogenic factor, recombinant polypeptides comprising an angiogenic factor operatively linked to a polypeptide comprising...
US20140234253 Combination Treatments For Hepatitis C  
The present invention features methods and pharmaceutical compositions for the treatment of Hepatitis C in a human in need thereof comprising administering a compound of Formula (I), (II), (III),...
US20140178451 ACTIVATORS OF CXCR3 FOR THE TREATMENT OF ANGIOPATHIES OF THE EYE  
The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by...
US20120076757 COMPOSITION FOR TRANSMUCOSAL DELIVERY OF POLYPEPTIDES  
The invention described herein provides an oral solid transmucosal dosage form that enhances transmucosal permeation of biologically active polypeptides across oral mucosal tissue and provides...
US20140328798 Co-Administration of a Parvovirus and a Cytokine for Therapy of Pancreatic Cancer  
The present invention relates to a combination of a parvovirus and a cytokine, preferably IFNγ, for use in treating pancreatic cancer, in particular a terminal stage of this disease.
US20150246973 Methods for treating skin infection by administering an IL-4R antagonist  
The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to...