Matches 1 - 50 out of 229 1 2 3 4 5 >


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US20140363391 SYSTEM AND METHOD FOR ADMINISTERING POLOXAMERS AND ANESTHETICS WHILE PERFORMING CPR AND MINIMIZING REPERFUSION INJURY  
According to an embodiment, a system for delivering a synthetic surfactant and an anesthetic to an individual to reduce reperfusion injury includes an anesthetic delivery device and a device for...
US20100310461 BINDING OF PATHOLOGICAL FORMS OF PROTEINS USING CONJUGATED POLYELECTROLYTES  
A method for treatment of a disease caused by aggregation of misfolded proteins including subjecting a body fluid of a patient to a separation of an aggregated misfolded protein which includes...
US20120148660 CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR  
The invention provides TLR agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma.
US20100310462 BINDING OF PATHOLOGICAL FORMS OF PROTEINS USING CONJUGATED POLYELECTROLYTES  
A method for separation of an aggregated misfolded protein from an environment including a non-aggregating normal form of the protein includes contacting both the misfolded and normal protein with...
US20120114590 IL28 AND IL29 TRUNCATED CYSTEINE MUTANTS AND ANTIVIRAL METHODS OF USING SAME  
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on...
US20100316719 B-1,3-GLUCAN-DERIVED POLYALDEHYDE/POLYAMINE HYDROGEL  
The present invention provides a combination product which comprises: (1) a polyaldehyde obtained by introducing an aldehyde group into a branched glucose in a β-1,3-glucan, and(2) a polyamine...
US20120076749 Modified Blood Factors Comprising a Low Degree of Water Soluble Polymer  
The present invention relates, in general, to materials and methods for the preparation of modified blood factors which have low levels of water soluble polymer molecules conjugated to the blood...
US20120114589 SWELLABLE BIODEGRADABLE POLYMERIC MATRICES AND METHODS  
The invention provides biodegradable polymeric hydrogel matrices having excellent durability and swellability. The matrices are formed from a combination of poly-α(1→4)glucopyranose macromer and a...
US20150157762 METHOD FOR BONE FORMATION BY ADMINISTERING POLY(LACTIC-CO-GLYCOLIC ACID) CROSS-LINKED ALENDRONATE  
A method for bone regeneration which comprises administering a short term release composition into a bone area of a subject in need thereof, wherein the composition comprises a...
US20130142733 MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES  
In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one...
US20140154202 PROCESS FOR THE IDENTIFICATION OF COMPOUNDS FOR TREATING CANCER  
Process for the identification of compounds for treating cancer. The invention relates to a method for identifying candidate compounds for use as therapeutic agents for the treatment of cancer,...
US20150217029 DRUG DELIVERY SCAFFOLD OR STENT WITH A NOVOLIMUS AND LACTIDE BASED COATING SUCH THAT NOVOLIMUS HAS A MINIMUM AMOUNT OF BONDING TO THE COATING  
Disclosed herein are drug delivery medical devices. A polymer coating for a medical device is provided which comprises a minimum amount of a drug bonded to the polymer in the coating.
US20120207700 SURFACE ACTIVE AGENT COMPOSITIONS AND METHODS FOR ENHANCING OXYGENATION, REDUCING BACTERIA AND IMPROVING WOUND HEALING AT A SITE OF TREATMENT  
This present invention relates generally to the use of novel formulations comprising a surface active polymer to enhance oxygenation in skin and other soft tissue. The present invention also...
US20150250898 NANOCOMPOSITES FOR IMAGING AND DRUG DELIVERY  
A composition (100) which includes a shell (120) comprising at least one lipid, wherein said shell defines an enclosed space, a gas (110) disposed within the enclosed space, and a coating (130) of...
US20130017166 Protein-Poly(2-oxazoline) Conjugates for Enhanced Cellular Delivery and Transport Across Biological Barriers  
The present invention provides polymer conjugates and methods of use thereof.
US20120156164 IN SITU-FORMING HYDROGEL FOR TISSUE ADHESIVES AND BIOMEDICAL USE THEREOF  
Disclosed herein are an in situ-forming, bioadhesive hydrogel and the medical uses thereof. Being formed by in situ crosslinking through an enzymatic reaction, the hydrogel has an advantage over...
US20150190421 POLOXAMERS FOR THE IMPROVEMENT OF RESPIRATORY FUNCTION  
Methods for treating or preventing a respiratory deficiency associated with a diaphragm muscle deficiency in a subject are provided, the method comprises administering to the subject in need...
US20130172405 COMPOSITIONS AND METHODS FOR SILENCING SMAD4  
The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target SMAD4 gene expression, lipid particles comprising...
US20140050689 TISSUE GRAFTED WITH A BIODEGRADABLE POLYMER  
Novel implantable tissue fixation methods and compositions are disclosed. Methods and compositions of tissue, fixed using polymeric and/or variable length crosslinks, and di- or polymercapto...
US20130280203 HIGH STABLE NON-IONIC N-VINYL BUTYROLACTAM IODINE AND PREPARATION METHOD THEREOF  
A preparation method of a high-stable non-ionic N-vinyl butyrolactam iodine solution is provided, wherein high-stable non-ionic N-vinyl butyrolactam iodine is dissolved in water, then citric acid,...
US20150104493 Dissolvable Strip for Treatment of Oral Thermal Burns  
A consumable film adapted to adhere and to dissolve in the oral cavity that provides a local anesthetic and therapeutic agents for the treatment of oral burns or injuries. The film is designed to...
US20140120150 Dissolvable Strip for Treatment of Oral Thermal Burns  
A consumable film adapted to adhere and to dissolve in the oral cavity that provides a local anesthetic and therapeutic agents for the treatment of oral burns or injuries. The film is designed to...
US20120014904 VASCULAR DELIVERY SYSTEMS  
The site-specific expression of selectins on endothelial cells of blood vessels during angiogenesis provides an opportunity to target anti-cancer drugs to the vascular endothelium to extend the...
US20140348772 PRODUCTION OF HYDROGELS BY MEANS OF DIELS-ALDER REACTION  
The present invention is directed to hydrogels and their preparation by cross-linking macromonomers by means of Diels-Alder reaction. The hydrogels described in the invention, which can gel in...
US20130101632 NANOPARTICULATE FORMULATIONS OF MITHRAMYCIN OR MITHRAMYCIN ANALOGUES FOR TREATING CANCER  
Methods and formulations for improving therapeutic potential of mithramycin (MTM) or MTM analogues are disclosed. For example, in certain aspects, methods for preparing a composition containing...
US20110060027 Aptamer Therapeutics Useful in the Treatment of Complement-Related Disorders  
The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders.
US20150030559 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES  
The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers...
US20110033412 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING SKELETAL MUSCLE DEFICIENCIES  
The present invention relates to compositions and methods for treating and preventing skeletal muscle deficiencies. In particular, the present invention provides compositions comprising poloxamers...
US20140004072 Polyethyleneimine And Beta2-Adrenergic Receptor Based Gene Therapy For Acute Lung Injury  
A method and a composition of gene therapy for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) based on polyplexes formed between linear polyethyleneimine (PEI) and...
US20140377209 SCAFFOLDS FORMED FROM POLYMER-PROTEIN CONJUGATES, METHODS OF GENERATING SAME AND USES THEREOF  
Conjugates are provided herein which comprise a protein attached to at least two polymeric moieties, at least one of which exhibits reverse thermal gelation. The conjugates are suitable for being...
US20080132440 Poly-Gamma-Glutamic Acid-Vitamin Complex and Use Thereof  
The present invention relates to PGA-vitamin complex containing poly-γ-glutamic acid(PGA), vitamin preparations containing said PGA-vitamin complex or cosmetic compositions. The inventive...
US20150147270 CONSTRUCTS FOR DIAGNOSING AND TREATING INFLAMMATORY BOWEL DISEASES AND COLON CANCER  
The present invention features, inter alia, constructs for the delivery of therapeutic and diagnostic agents to a patient. The constructs can include a nanoparticle, a targeting agent that...
US20140271526 ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT  
The present invention relates to veterinary compositions and methods of treating and/or preventing mastitis in non-human mammals. More particularly, the present invention relates to the treatment...
US20150023875 System for Targeted Delivery of Therapeutic Agents  
The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides...
US20150182667 Composition with Biofilm Dispersal Agents  
Embodiments of the presently-disclosed subject matter provide composites that comprise a tissue graft and a biofilm dispersal agent. The tissue graft can be bone tissue graft, a soft tissue graft,...
US20130129662 Compositions and Methods for the Treatment of Heart Failure  
The invention provides a therapeutic composition comprising an aqueous buffer, and a therapeutic agent that proves the functioning of a diseased heart by decreasing left ventricular end-diastolic...
US20100297056 COMPOSITION BASED ON PERHYDROSQUALENE AND COLLAGEN-POLYVINYLPYRROLIDONE FOR FILLING MINOR CUTANEOUS DEPRESSIONS  
The present invention concerns a composition based on collagen-polyvinylpyrrolidone and perhydrosqualene for filling by intracutaneous delivery route minor depressions of the skin in order to...
US20130039878 TRIPLE CROSS-LINKED COLLAGEN, METHOD OF MANUFACTURING THE SAME, AND USE THEREOF  
The present invention relates to a method for manufacturing a triple cross-linked collagen, which comprises the following steps: providing a soluble collagen sample; mixing the collagen sample...
US20050191270 Anti-infectious hydrogel compositions  
The present invention provides a hydrogel composition capable of preventing the intrusion of micro-organisms into body cavities or body openings of mammals comprising of a poly(N-vinyl lactam), a...
US20130183262 ANTIMICROBIAL POLYMERIC COMPOSITIONS  
A compound having the formula: wherein n, y, R1 and R2 are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect...
US20120171152 Amphiphilic Polymer-Protein Conjugates and Methods of Use Thereof  
Compositions and methods for transporting biologically active proteins and polypeptides, particularly across the blood-brain barrier, are provided.
US20060198813 Substituted fullerene compositions and their use in treatment of shock  
This patent discloses the use of substituted fullerenes in the treatment of shock. The substituted fullerenes comprise a fullerene core (Cn) and at least one of: (i) from 1 to 6 (>CX1X2) groups...
US20140348773 ARTIFICIAL BONE IMPLANTS, OR BONE GRAFTS, OF POLYMERIC COMPOSITES WITH BONE FORMING PROPERTIES  
The present invention relates to methods for providing polymeric composites with bone forming, such as with osteogenic and/or osteoinductive and/or osteoconductive, properties. The present...
US20120100096 CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS  
The present invention relates to conjugates of small-interfering nucleic acids (siNA). Compositions of siNA suited for administration to a patient are described. Methods for delivering the...
US20060177413 Carbohydrate modifiers of neuronal growth  
Fucose galactose carbohydrates have been shown to induce neuronal outgrowth. The invention includes methods of inducing neuronal outgrowth using carbohydrates, assemblies, and polymers bearing...
US20110044929 FORMULATIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES  
The present inventors have developed a novel composition and method for inhibiting inflammation and treating of symptoms of tissue ischemia, including that associated with peripheral and cardiac...
US20070048250 Methods of treating concomitant constipation in a cancer treatment regimen including imexon  
Methods of treating imexon-induced constipation in patients in conjunction with their participation in a cancer treatment regimen are disclosed herein. Embodiments of the invention include the...
US20130330293 BIO-NANO POWER CELLS AND THEIR USES  
The present invention concerns bio-nano power cells and methods of their manufacture and use. More particularly, the present invention relates to the preparation of bio-nano power cells that are...
US20120156135 PARTICLES WITH MULTIPLE FUNCTIONALIZED SURFACE DOMAINS  
This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic pattern. The disclosure also provides...
US20120164098 CROSSED-LINKED HYALURONIC ACID AND COLLAGEN AND USES THEREOF  
The present invention discloses a cross-linked hyaluronic acid/collagen formulation which has improved composition for dermal filling and higher persistence than cross-linked collagen or HA alone....

Matches 1 - 50 out of 229 1 2 3 4 5 >