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US20110305777 DIMERIC IAP ANTAGONISTS  
Smac mimetics that inhibit IAPs.
US20140186468 DIAGNOSING SUBSETS OF TRIPLE-NEGATIVE BREAST CANCER  
The present invention provides a unique combination of biomarkers that identify triple-negative breast cancer (TNBC) patient subpopulations. Such subpopulations will have differential responses to...
US20140170241 COILED COIL HELIX CRISTAE MORPHOLOGY 1 (CHCM1) TUMOR MARKER AND CANCER THERAPEUTIC TARGET  
Methods for diagnosing and treating a cancer or a tumor in a patient are provided. The methods can comprise the steps of obtaining a biological sample from the patient and analyzing the sample for...
US20120201747 System and Method for Diagnosis and Treatment  
This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy...
US20110287110 COMBINATION CANCER TREATMENT  
Described herein are methods of inhibiting the proliferation of cancer cells and methods of treating cancer, by administering a combination of a copper chelator and a platinum-based chemotherapeutic.
US20130121912 MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
US20120171306 THERAPEUTIC TREATMENT OF CANCER AND DYSPLASIA OF THE CERVIX OR VAGINA USING ESTROGEN ANTAGONISTS  
A method for treatment of cervical or vaginal cancer and their associated dysplasia, including the steps of identifying a human cervical or vaginal cancer and/or dysplasia patient, administering an...
US20120100134 GENETIC VARIANTS IN ANGIOGENESIS PATHWAY ASSOCIATED WITH CLINICAL OUTCOME  
The invention provides methods for determining the clinical outcomes for treatment with various treatment regimens available to cancer patients based on genotypes of the patients for genetic...
US20140186264 EXTRACELLULAR VESICLE-ASSOCIATED PROTEIN MARKERS OF CANCER  
Extracellular vesicle-associated protein biomarkers for use in diagnosing and staging carcinomas, e.g., lung and ovarian cancers.
US20110286937 SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME  
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
US20110117078 Methods for the Treatment of Cancers  
Methods for the treatment of cancers involving dysregulation of thromboxane receptor β (TP-β) are provided, including in certain aspects methods for diagnosing such cancers. Specific cancers i...
US20110171323 METHODS AND KITS TO PREDICT PROGNOSTIC AND THERAPEUTIC OUTCOME IN SMALL CELL LUNG CANCER  
Disclosed herein are methods used in the identification of cancer patients likely or unlikely to respond to systemic chemotherapy, methods of treating cancer patients based upon the identification,...
US20140227284 SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER  
Described herein are compounds, compositions and methods for treatment of cancer. Also described are methods and uses for identifying subject with cancer that are suitable for treatment with the...
US20130236567 GENE EXPRESSION SIGNATURE AS A PREDICTOR OF CHEMOTHERAPEUTIC RESPONSE IN BREAST CANCER  
Disclosed are methods and compositions for determining and/or predicting a response to a therapy, especially a cancer therapy, including chemotherapy. Specifically, the disclosure provides profiles...
US20120230952 DETECTION OF BLADDER CANCER  
Provided are methods for detecting bladder cancer in a subject. In some aspects, methylation of one or more of MYO3A, CA10, NKX6-2, SOX11, DBC1, NPTX2, and/or A2BP1 in DNA sediment from a urine...
US20120034318 DIAGNOSTIC METHOD USING PALB2  
The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also...
US20120070502 METHODS OF TREATING CANCER  
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an...
US20110052672 TREATMENTS OF DISEASE OR DISORDERS USING NANOPARTICLES FOR FOCUSED HYPERTHERMIA TO INCREASE THERAPY EFFICACY  
Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of...
US20110171228 Methods and Compositions Relating to the Regulation of Apoptosis by MUC1 and BH3-Containing Proapoptotic Proteins  
This invention relates to regulation of cell signaling, cell growth, and more particularly to the regulation of cancer or immune cell growth. The invention provides methods of inhibiting...
US20140079813 Genes Associated With Post Relapse Survival And Uses Thereof  
Provided are methods, systems and kits for predicting post-relapse survival of a cancer patient and for identifying cancer genes predictive of the post-relapse survival of the patient. Values...
US20110142917 COMPOSITIONS AND METHODS FOR TREATMENT OF EAR DISORDERS  
The present invention relates to pharmaceutical compositions useful for topical, non-invasive delivery of an oligonucleotide to the ear and to methods for the treatment of an ear disorder,...
US20110311651 CARDENOLIDES FOR THE TREATMENT OF OCULAR CANCER  
The instant invention provides methods of using a class of compounds known as cardenolides in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides...
US20140234295 ISOFLAVONOID COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER  
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in cancer...
US20120207809 Method and system for effecting changes in pigmented tissue  
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are...
US20110118528 Methods and Nutritional Formulations to Increase the Efficacy and Reduce the Side Effects of Cancer Treatment  
The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides...
US20120321552 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20110104050 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20120237502 METHOD FOR TREATING BREAST CANCER AND OVARIAN CANCER  
The present invention relates to a method for the prevention or treatment of certain breast cancers or ovarian cancer comprising administering to a patient in need thereof of a therapeutically...
US20110076343 Multiple Myeloma Treatments  
Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.
US20110059074 Knowledge-Based Proliferation Signatures and Methods of Use  
The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a...
US20110033461 Combination Therapy for the Treatment of Cancer  
Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed.
US20120323163 METHODS OF USING DUAL-EFFECT LIPOSOME IN THERAPY  
The invention provides a method for treating target in need of such a treatments in a subject, comprising (a) administering a liposome containing a photosensitizer and a drug to a subject and (b)...
US20130122063 Nanotubes as Mitochondrial Uncouplers  
A method of uncoupling mitochondria in a subject including administering nanotubes to the subject in a therapeutically effective amount, wherein the nanotubes are self-rectifying is provided. A...
US20130202717 MATERIALS AND METHODS FOR DIAGNOSING AND PREDICTING THE COURSE OF PROSTATE CANCER  
Expression of Forkhead-box protein A1 (FOXA1), a transcription factor important for the normal development of the prostate gland is thought to be controlled by steroid hormones and GATA-3....
US20110262560 Pigmented Emulsion Makeup Compositions With Gemstones  
A pigmented emulsion composition comprising a water phase, an oil phase, and a plurality of gemstones in particulate form, and a method for providing a glow to the skin and ameliorating the...
US20120082736 Small-molecule TNF modulator to reduce the side effects of chemotherapy and radiotherapy  
Cancer patients treated by chemotherapy and/or radiotherapy often suffer serious side effects. Currently, there is only one FDA approved and used as both a chemoprotector and a radioprotector,...
US20110044906 Methods for the Treatment, the Prognostic Assessment and the Staging of Non-Small Cell Lung Cancer  
The present invention relates to methods for the treatment, the prognosis and the diagnosis of non-small cell lung cancer.
US20110280963 COMBINATION THERAPY FOR THE TREATMENT OF CANCER  
The present invention provides methods of sensitizing lung cancer cells to cisplatin and inhibiting the growth of lung cancer tumors by employing a modified eIF-4E antisense oligonucleotide and...
US20120141603 METHODS AND COMPOSITIONS FOR LUNG CANCER PROGNOSIS  
Disclosed herein are methods and materials for prognosing survival of lung cancer patients, the methods comprising the detection of gains and losses of minimal common regions and/or genes...
US20110311629 NON-ADHESIVE ELASTIC GELATIN MATRICES  
The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix...
US20110097402 NON-ADHESIVE ELASTIC GELATIN MATRICES  
The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix...
US20110243921 PREVENTION AND TREATMENT OF CUTANEOUS LUPUS ERYTHEMATOSUS  
Disclosed herein, in certain embodiments, are methods and compositions for the prevention and treatment of autoimmune disease. Further disclosed herein, in certain embodiments, are methods for the...
US20120015049 MICRORNA BIOMARKER IN CANCER  
This invention provides compositions and methods for predicting and improving a chemotherapy response to treat an ovarian cancer. In one embodiment, the invention provides compositions and methods...
US20140170239 METHODS FOR SCREENING INHIBITORS OF TUMOR ASSOCIATED PROTEIN AGGREGATION  
The disclosure relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt...
US20140314834 GLA MONOTHERAPY FOR USE IN CANCER TREATMENT  
The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.
US20140248375 Combination Therapy for Treating Proliferative Diseases  
The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.
US20140220006 LUNG CANCER BIOMARKERS  
The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of...
US20120282245 BIOMARKERS AND ASSAYS FOR THE TREATMENT OF CANCER  
This invention features methods for prognosticating the efficacy of a cancer treatment comprising administration of a lymphotoxin-β receptor (LT-β-R) using TRAF3, TRAF2, and/or p53 markers, as w...
US20140302174 Combination Therapy for Ovarian Cancer  
The present invention provides a method of treating ovarian cancer in a mammal in need of such treatment comprising administering an effective amount of a combination of gemcitabine, cisplatin or...
US20110189250 GREEN APPROACH IN METAL NANOPARTICLE-EMBEDDED ANTIMICROBIAL COATINGS FROM VEGETABLE OILS AND OIL-BASED MATERIALS  
The present invention generally relates to a method of making nanoparticles and uses thereof. In particular, the invention relates to methods of making metal nanoparticles (MNPs). The invention...