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US20110293701 MULTIVALENT SYNTHETIC NANOCARRIER VACCINES  
The invention relates, at least in part, to compositions comprising populations of synthetic nanocarriers that comprise different sets of antigens as well as related methods.
US20110287085 LIPOSOMAL CURCUMIN FOR TREATMENT OF CANCER  
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of...
US20140328937 Drug Delivery Systems and Use Thereof  
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such...
US20130209570 DRUG DELIVERY SYSTEMS AND USE THEREOF  
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such...
US20140294986 Microsphere Drug Delivery System for Sustained Intraocular Release  
Disclosed are biodegradable microspheres between 40 μm and 200 μm in diameter that are effectively retained in the anterior chamber of the eye without producing hyperemia. The microspheres...
US20140314865 Vaccine Nanotechnology  
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune...
US20130287857 Vaccine Nanotechnology  
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune...
US20140065233 INJECTABLE MICROSPHERES FOR DERMAL AUGMENTATION AND TISSUE BULKING  
The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions...
US20130323316 INJECTABLE MICROSPHERES FOR DERMAL AUGMENTATION AND TISSUE BULKING  
The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions...
US20140193508 SURFACE BINDING OF NANOPARTICLE BASED DRUG DELIVERY TO TISSUE  
Microparticles and nanoparticles and compositions thereof are provided. The microparticles and nanoparticles and compositions may be used for the treatment of musculoskeletal disease, such as...
US20140037749 Delivery Scaffolds and Related Methods of Use  
The present invention relates to delivery systems. In particular, the present invention provides microporous scaffolds having thereon agents (e.g., extracellular matrix proteins, exendin-4) and...
US20150216810 CONTROLLED RELEASE HYDROCODONE FORMULATIONS  
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt...
US20110217384 Modified Release Dosage Forms of Skeletal Muscle Relaxants  
A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion...
US20150004243 OIL-IN-WATER METHOD FOR MAKING POLYMERIC IMPLANTS CONTAINING A HYPOTENSIVE LIPID  
Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the subconjunctival space, in facilitating...
US20150196516 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION  
Pharmaceutical formulations are described for use in the treatment of pulmonary arterial hypertension (PAH). The formulations comprise polymeric nanoparticles encapsulated within crosslinked...
US20130323177 TUMOR-TARGETING GAS-GENERATING NANOPARTICLE, METHOD FOR PREPARING THE SAME, AND TUMOR-TARGETING NANOPARTICLE FOR DRUG DELIVERY USING THE SAME  
A tumor-targeting gas-generating nanoparticle, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same relate to a tumor-targeting gas-generating nanoparticle...
US20100303923 Endotoxin adsorbent for the prevention and treatment of autoimmune diseases  
It is believed that the abnormal absorption of endotoxin present in the gastrointestinal tract relates to the pathogenesis of autoimmune diseases such as rheumatoid arthritis. In an animal model...
US20110008453 Stable Corticosteroid Nanoparticulate Formulations And Methods For The Making And Use Thereof  
Disclosed are stable corticosteroid nanoparticulate formulations, methods of making and therapeutic uses thereof.
US20140314867 VITAMIN K2 MICROSPHERES  
A vitamin K2 microsphere. The microsphere includes a poly(lactide-co-glycolide) acid (PLGA) particle, in which the Mw of PLGA is between 1000 and 300000, and the molar ratio between the lactide...
US20140099382 TREATMENT USING DANTROLENE  
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH)...
US20110020427 Method Of Treating Malignant Solid Tumors Using Transcatheter Arterial Chemoembolization (TACE)  
This invention is directed to methods of treating solid tumor cancers, particularly refractory cancers by administration of two pluralities of microparticles, one comprising drug-carrying...
US20150044296 COMBINATION THERAPY TO IMPROVE JOINT, TENDON, AND LIGAMENT HEALING  
The present invention is directed to kit, drug combinations and methods for promoting endogenous bone marrow (BM)-derived vasculogenic progenitor cell (PC) mobilization, sensitization of such...
US20110081422 PROLONGED RELEASE OF LOCAL ANESTHETICS USING MICROPARTICLES AND SURGERY APPLICATIONS  
Methods and compositions for providing long term pain relief in, for example, surgery recovery, including injecting a composition comprising a plurality of microparticles having different sizes...
US20110091564 INJECTABLE HOLLOW TISSUE FILLER  
The present invention comprises a plurality of injectable hollow particulate fillers suspended in a biocompatible fluid carrier to significantly improve the clumping resistance and injectability...
US20150157762 METHOD FOR BONE FORMATION BY ADMINISTERING POLY(LACTIC-CO-GLYCOLIC ACID) CROSS-LINKED ALENDRONATE  
A method for bone regeneration which comprises administering a short term release composition into a bone area of a subject in need thereof, wherein the composition comprises a...
US20140314868 PROSTAGLANDIN AND PROSTAMIDE DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF  
Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma.
US20110129541 SUSPENSION DELIVERY SYSTEM FOR THE SUSTAINED AND CONTROLLED LOCAL RELEASE OF PHARMACEUTICALS  
The invention relates to a novel suspension delivery system for the sustained and controlled release of pharmaceuticals. Methods of preparation and use are also disclosed.
US20100329982 PARTICLES WITH INDUCIBLE CHANGE OF SHAPE  
The invention relates to particles which exhibit a stimulable shape change and allow control of their uptake in active cells. The particles can be used as carrier systems for bioactive molecules...
US20110008456 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders  
Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal,...
US20100297251 ENCAPSULATED PARTICLES FOR ENTERIC RELEASE  
The present invention provides a system for delivery of an enteric coated active agent generally resistant to disintegration in an neutral environment having one or more active agents encapsulated...
US20150017250 TAMPER-RESISTANT DOSAGE FORM CONTAINING ETHYLENE-VINYL ACETATE POLYMER  
The invention relates to a tamper-resistant, oral pharmaceutical dosage form comprising a pharmacologically active ingredient having psychotropic action and an ethylene-vinyl acetate (EVA) polymer...
US20130295191 Stable Formulations for Lyophilizing Therapeutic Particles  
The present disclosure generally relates to lyophilized pharmaceutical compositions comprising polymeric nanoparticles which, upon reconstitution, have low levels of greater than 10 micron size...
US20140302159 Cosmetic composition comprising a superabsorbent polymer and a lamellar or platelet-shaped matting mineral filler  
The present invention relates to a composition for topical application, comprising at least one aqueous phase, at least one superabsorbent polymer and at least one lamellar or platelet-shaped...
US20080175921 Colloidal formulation of long-acting insulin and its preparation  
The invention relates to injectable long-acting insulin formulations for the treatment of type I and II diabetes in humans and animals. The main objective of the invention is to provide a...
US20130280338 TAMPER RESISTANT AND DOSE-DUMPING RESISTANT PHARMACEUTICAL DOSAGE FORM  
A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected...
US20140314866 MATERIALS AND METHODS FOR MODULATING IMMUNE RESPONSES  
The present invention provides nanoparticle-coupled tolerogenic Treg cell therapy for treatment of immune and/or autoimmune disorders. In certain specific embodiments, the present invention can be...
US20110151015 IMMUNOMODULATOR PARTICLES AND METHODS OF TREATING  
A method of stimulating an immune response in a subject including administering a micrometer-sized particle coupled with an antigen to the subject, wherein increasing the aspect ratio of the...
US20100297252 NANOPARTICULATE MELOXICAM FORMULATIONS  
The present invention is directed to nanoparticulate compositions comprising meloxicam particles having an effective average particle size of less than about 2000 nm.
US20130323317 INJECTABLE AND SWELLABLE MICROSPHERES FOR TISSUE BULKING  
The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The...
US20100323026 SUSTAINED RELEASE PREPARATION FOR TISSUE REGENERATION THERAPY  
The object of the present invention is to provide a microsphere which has a slow-release period of from about two weeks to about four weeks following administration, enables a higher content of a...
US20110135744 Nanoparticle Based Therapy for Dispersing Mucin  
There are provided compositions and methods to disperse mucin and/or actin using nanoparticles wherein the average diameter of the nanoparticles is less than about 1000 nm.
US20110059183 WATER-INSOLUBLE MEDICINE  
A method of producing water-insoluble anti-cancer drug in the form of particulates, the method including preparing a water-insoluble anti-cancer drug having at least one multiple bond in the...
US20110052712 Sprayable Polymers As Adhesion Barriers  
A formulation for generating an adhesion barrier that includes a plurality of particles or a dry powder that is made of a polymer combination of at least one biodegradable polymer and at least one...
US20110150971 ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING  
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier...
US20110150970 ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING  
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier...
US20110150969 ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING  
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier...
US20130251817 CANCER CELL TARGETING USING NANOPARTICLES  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
US20130251816 CANCER CELL TARGETING USING NANOPARTICLES  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
US20150132399 COMPOSITION AND METHOD FOR SULFATED NON-ANTICOAGULANT LOW MOLECULAR WEIGHT HEPARINS IN CANCER AND TUMOR METASTASIS  
A nanoformulation that includes nanoparticles. Each nanoparticle includes a shell in which a glycosaminoglycan (GAG is encapsulated. The GAG is ionically or covalently bonded to the shell. The GAG...
US20140335193 CONTROLLED-RELEASE INJECTABLE MICROPARTICLE  
The invention relates to a controlled-release injectable microparticle comprising a polyvinyl alcohol polymer and one or more hormones, in particular progesterone. Said microparticle induces...

Matches 1 - 50 out of 393 1 2 3 4 5 6 7 8 >