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US20120034305 SOLID DISPERSING VACCINE COMPOSITION FOR ORAL DELIVERY  
The invention disclosed herein relate to an oral vaccine in which the vaccine composition and adjuvant(s) are carried on a solid fast-dispersing dosage form. The vaccines are targeted toward...
US20110151005 METHODS AND MEANS FOR SOFT TISSUE ENGINEERING  
Cellfree adipose tissue extracts, implants including the same and methods for the preparation thereof. The extracts and implants are capable of inducing adipogenesis and angiogenesis and are,...
US20110196502 Methods of Using Water-Soluble Inorganic Compounds for Implants  
A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic...
US20120148671 GASTRIC RETAINED GABAPENTIN DOSAGE FORM  
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form.
US20140242170 Corticosteroids for the Treatment of Joint Pain  
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing,...
US20110293721 PIROXICAM-CONTAINING MATRIX PATCHES AND METHODS FOR THE TOPICAL TREATMENT OF ACUTE AND CHRONIC PAIN AND INFLAMMATION THEREWITH  
This invention relates to matrix patches for the topical (i.e., transdermal) delivery of piroxicam and methods for the treatment of acute and chronic pain and inflammation therewith, particularly...
US20120207837 BIOERODIBLE MATRIX FOR TISSUE INVOLVEMENT  
Disclosed herein are polyurethane polymer matrices with a porosity of from about 20 microns to about 90 microns that are useful in promoting closure and protection of incision sites; supporting...
US20110064810 TISSUE ENGINEERING METHOD FOR ORGAN RECONSTRUCTION USING INJECTABLE MATRIX  
The various embodiments herein relate to an injectable matrix used for regeneration, reconstruction, repair or replacement of organ or tissue. The injectable matrix consists of a synthetic and...
US20100316720 Use of an extract from snow algae in cosmetic or dermatological formulations  
The present invention relates to the use of an extract from snow algae, especially an extract from Chlamydocapsa sp (snow algae) in cosmetic and/or pharmaceutical products. More particularly, the...
US20120114754 RAPIDLY DISINTEGRATING SOLID ORAL DOSAGE FORM  
Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water-dispersible excipient,...
US20120107394 IMMUNO-COMPATIBLE HYDROGEL SYSTEM  
An immuno-compatible hydrogel system is provided that is resistant to protein binding. The hydrogel system is prepared by contacting a hydrogel solution with a cross-linking agent to form a gel,...
US20110097406 METHODS AND COMPOSITIONS FOR RETAINING ECM MATERIALS IN HYDROGELS  
The present invention provides cell-laden and/or extracellular matrix material laden hydrogels for use in tissue engineering and methods for producing such hydrogels. In some particular...
US20110066182 Tissue Sealant for Use in Non Compressible Hemorrhage  
ClotFoam is a surgical sealant and hemostatic agent designed to be used in cases of non-compressible hemorrhage. It can be applied in the operating room through laparoscopic ports, or directly...
US20120034306 POLYMERIC DRUG DELIVERY SYSTEMS AND PROCESSES FOR PRODUCING SUCH SYSTEMS  
The subject invention relates to implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants.
US20150182456 HYDROGEL VACCINE FORMULATIONS  
This invention relates to compositions for delivering one or more active ingredients, and more particularly to compositions, e.g. beads, comprising a matrix material which matrix material...
US20120294938 PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION WITH CONTROLLED ACTIVE INGREDIENT RELEASE IN THE SMALL INTESTINE AND METHOD FOR ITS PRODUCTION  
Any pharmaceutical preparation for oral administration with controlled release of active ingredient in the small bowel, on the basis of active ingredient carriers provided with at least one active...
US20110052505 Post-biopsy cavity treatment implants and methods  
A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix...
US20110104282 New Therapy of Treatment of the Irritable Bowel Syndrome  
The invention provides for new methods for treatment and diagnosis of irritable bowel syndrome (IBS). In particular, there is disclosed the use of a Chlamydia activating agent and one or several...
US20150118309 PREPARATION FOR PERCUTANEOUS ABSORPTION CONTAINING ROTIGOTINE  
Exemplary embodiments of the present invention relate to a method for preparing a preparation for percutaneous absorption, which includes rotigotine as an active ingredient, and more specifically,...
US20150098997 Methods and Compositions for Treating Attention Deficit Hyperactivity Disorder, Anxiety and Insomnia Using Dexmedetomidine Transdermal Compositions  
Aspects of the invention include methods of treating ADHD, anxiety or insomnia by applying a transdermal delivery device containing a dexmedetomidine composition formulated to deliver an amount of...
US20120282340 DRUG DELIVERY SYSTEM  
The present invention relates to drug delivery systems in the form of thin water-soluble films (wafers), which contain an Estrogen Receptor beta (ER-β) selective agonist. The wafers of the present...
US20100330141 PRODUCT FOR ABSORPTION PURPOSES  
A product for absorption purposes comprises a water insoluble support matrix substituted with a hydrophobic entity and a positively charged entity. The hydrophobic entity comprises di-alkyl...
US20110236454 INJECTABLE DRUG DELIVERY FORMULATION  
The invention provides an injectable formulation that includes an active agent; a biocompatible solvent system, crosslinkable polymers such as polysaccharides; and crosslinking agents; wherein the...
US20100316719 B-1,3-GLUCAN-DERIVED POLYALDEHYDE/POLYAMINE HYDROGEL  
The present invention provides a combination product which comprises: (1) a polyaldehyde obtained by introducing an aldehyde group into a branched glucose in a β-1,3-glucan, and(2) a polyamine...
US20110020451 TAMPER-RESISTANT DOSAGE FORM FOR OXIDATION-SENSITIVE OPIOIDS  
Thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, comprising an opioid (A),a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%,...
US20120183606 DRUG DELIVERY SYSTEM COMPRISING POLYOXAZOLINE AND A BIOACTIVE AGENT  
The invention relates to drug delivery systems comprising a water-soluble polymer matrix and a bioactive agent entrained therein, said water soluble polymer matrix containing at least 50 wt. % of...
US20110052685 GASTRIC RETENTIVE PHARMACEUTICAL COMPOSITIONS FOR IMMEDIATE AND EXTENDED RELEASE OF ACETAMINOPHEN  
Gastric retentive dosage forms for extended release of acetaminophen or for both immediate and extended release of acetaminophen are described. The dosage forms allow effective pain relief upon...
US20110293720 PROGESTIN-CONTAINING DRUG DELIVERY SYSTEM  
The present invention relates to drug delivery compositions in the form of thin water-soluble films (wafers), which contain small particles that comprise at least one progestin and at least one...
US20150050341 METHODS AND COMPOSITIONS FOR RNAI-BASED CANCER TREATMENT  
The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers.
US20130280329 METHODS AND COMPOSITIONS FOR RNAI-BASED CANCER TREATMENT  
The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers.
US20110104281 METHOD FOR TREATING PAIN USING A SUBSTITUTED 2-AMINOTETRALIN COMPOUND  
A method for treating pain, particularly non-inflammatory musculoskeletal pain such as myofascial pain or back pain, in a subject comprises administering to the subject a substituted...
US20110151003 TRANSDERMAL SYSTEMS CONTAINING MULTILAYER ADHESIVE MATRICES TO MODIFY DRUG DELIVERY  
A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the...
US20120107383 OSTEOCONDUCTIVE MATRICES COMPRISING CALCIUM PHOSPHATE PARTICLES AND STATINS AND METHODS OF USING THE SAME  
Osteoconductive matrices and methods are provided that have one or more statins disposed in calcium phosphate particles. The matrices may be injected into a fracture site. The osteoconductive...
US20110097405 ESTRADIOL-CONTAINING DRUG DELIVERY SYSTEM  
The present invention relates to drug delivery systems in the form of thin water-soluble films (wafers), which contain estradiol, or derivatives thereof, in low amounts. The wafers of the present...
US20140141079 PRAMIPEXOLE ONCE-DAILY DOSAGE FORM  
An orally deliverable pharmaceutical composition comprises a therapeutically effective amount of pramipexole or a pharmaceutically acceptable salt thereof and at least one pharmaceutically...
US20100316718 ACTIVATED FOAM  
The present invention relates to an activated foam made of a natural or synthetic rubber or a synthetic resin, characterized in that the foam contains a zirconium compound and/or a germanium...
US20130039981 Quick Dissolving, Long Acting Zinc Therapeutic Formulations  
The present invention comprises a quick dissolving, long acting zinc therapeutic cold formulation containing high levels of an active compound encapsulated within bioadhesive/muco-adhesive...
US20130171256 ALCOHOL-RESISTANT EXTENDED RELEASE DOSAGE FORMS COMPRISING VENLAFAXINE  
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing venlafaxine or a pharmaceutically...
US20090142400 ANALGESIC COATED MEDICAL PRODUCT  
Described are medical products including an analgesic such as lidocaine, bupivicaine, or a mixture thereof. Such medical products can find use in pain relief, particularly after surgery, and can...
US20110104273 GASTRIC RETENTIVE PHARMACEUTICAL COMPOSITIONS FOR IMMEDIATE AND EXTENDED RELEASE OF PHENYLEPHRINE  
Gastric retentive dosage forms for both immediate and extended release of phenylephrine are described which allow once- or twice-daily dosing. Methods of treatment using the dosage forms and...
US20110256201 HYDROLYZED HYDROGELS  
The invention provides methods of making hydrolyzed cross-linked polyvinyl alcohol (PVA) hydrogels by polymerizing vinyl acetate (VAc) monomers to polyvinyl acetate (PVAc) polymer network by...
US20120141583 ALCOHOL RESISTANT DOSAGE FORMS  
Opioid controlled release formulation resistant to alcohol extraction of the opioid.
US20110165248 PHARMACEUTICAL DOSAGE FORMS COMPRISING POLY(E-CAPROLACTONE)  
The present invention relates to pharmaceutical dosage forms, for example to pharmaceutical dosage forms comprising poly(ε-caprolactone), and processes of manufacture, uses, and methods of...
US20110217371 CONTROLLED-RELEASE MICROPARTICLES AND METHOD OF PREPARING SAME  
Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a...
US20130171257 EXTENDED RELEASE OPIOID ABUSE DETERRENT COMPOSITIONS AND METHODS OF MAKING SAME  
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
US20120087982 EXTENDED RELEASE OPIOID ABUSE DETERRENT COMPOSITIONS AND METHODS OF MAKING SAME  
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
US20100303911 Hydrogel systems  
A method of in situ hydrogel polymerization is provided. The method comprises combining a backbone polymer with an in situ polymerizable group to form a prepolymer solution which is administered...
US20110111033 HYDROGEL WITH COVALENTLY CROSSLINKED CORE  
A novel hydrogel system is provided. The hydrogel system comprises a biocompatible hydrogel core having dispersed therein a covalently crosslinked polymer matrix. The hydrogel system is useful per...
US20130115282 POLYVALENT POLYMERIC MATRIX FOR MODIFIED RELEASE SOLID ORAL PREPARATIONS AND METHOD OF PREPARATION THEREOF  
A polymeric matrix for oral administration with modified release and taste masking properties is disclosed, obtained without using inert supports such as sugar spheres, comprising particles of...
US20120269893 Compositions Comprising Solid Particles Encapsulated In A Cross-Linked Silicone Matrix, And Methods Of Making The Same  
The present invention relates to topical compositions containing solid particles that are stabilized via encapsulation into a cross-linked silicone matrix. The solid particles are preferably...