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US20140141053 MICROLAYER COEXTRUSION TO CREATE A TIME-RELEASE DRUG SUBSTANCE DELIVERY PRODUCT  
The present invention relates to medical devices containing time-release drug substance, and more particularly, to medical tubing, catheters, stents, cables (including fiber optic cables), pills,...
US20120321705 Lineage Restricted Glial Precursors from the Central Nervous System  
A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5+ E-NCAM− glial-restricted precursor (GRP) cells are capable of differentiating into...
US20110135718 VIRAL PARTICLE-LIKE STRUCTURE IN PHYSIOLOGICAL CONDITIONS, AND METHOD OF FORMING IT  
There is provided a novel method of forming uniform viral particles under physiological conditions. The method of forming uniform-sized viral particle aggregates composed of viral protein is...
US20140093560 METHODS AND MATERIALS FOR THE TREATMENT OF TESTOSTERONE DEFICIENCY IN MEN  
The present invention relates to the use of compositions comprising trans-clomiphene for treating men with hypogonadism. The invention is also directed to methods for treating males with hypogonadism.
US20130337055 COMPOSITIONS, METHODS OF TREATMENT AND DIAGNOSTICS FOR TREATMENT OF HEPATIC STEATOSIS ALONE OR IN COMBINATION WITH A HEPATITIS C VIRUS INFECTION  
The present invention is directed to pharmaceutical compositions and methods of treatment that relate to the inhibition, resolution and/or prevention of an array of the manifestations of metabolic...
US20140105971 MICROPOROUS ZIRCONIUM SILICATE FOR THE TREATMENT OF HYPERKALEMIA IN HYPERCALCEMIC PATIENTS AND IMPROVED CALCIUM-CONTAINING COMPOSITIONS FOR THE TREATMENT OF HYPERKALEMIA  
The present invention relates to novel calcium-containing microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at...
US20150098992 COMPOSITE FORMULATION COMPRISING MULTI-UNIT SPHEROIDAL TABLET (MUST) ENCAPSULATED IN HARD CAPSULE AND METHOD FOR PREPARING SAME  
Provided is a composite formulation comprising multi-unit spheroidal tablets (MUSTs) encapsulated in a hard capsule and a method for preparing same. The inventive hard capsule composite...
US20150024043 Medi-Cap (Bio-Absorbable Capsules)  
Medi-Cap a specialized absorbable capsule of various shapes and sizes. It may come prefilled with desired medication or material or it can come in a two-piece snap together capsule that can be...
US20110177163 COMPOSITIONS AND METHODS FOR TREATING HEPATITIS A  
The present application provides compositions and methods useful for treating hepatitis A. In particular, while hepatitis A vaccines are currently limited to parenteral administration routes...
US20120135069 NANONIZED TESTOSTERON FORMULATIONS FOR IMPROVED BIOAVAILABILITY  
Nanonized formulations of testosterone esters, especially testosterone undecanoate, and of testosterone are prepared which show an enhanced oral bioavailability compared to the existing oral...
US20130189355 COMPOSITIONS AND METHODS FOR LOWERING LEVELS OF HIGH-SENSITIVITY (HS-CRP) IN A SUBJECT  
The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in...
US20140044760 STABLE, FLOWABLE SILICA CAPSULE FORMULATION  
A flowable, stable silica capsule formulation composed of a silica capsule suspension and an adjuvant for use in a personal care product, a beauty care product, a fabric care product, a home care...
US20130129818 NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES  
Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized...
US20150147388 Materials and Methods for Modulating immune Responses  
The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial lymph-node homing environment, and a...
US20140286865 SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM  
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active...
US20120288560 Methods for the Treatment of CNS-Related Conditions  
The invention provides methods for treating CNS-related conditions with amantadine and donepezil, in which the amantadine is in an extended release form, wherein the extended release amantadine...
US20130230576 MICROLAYER COEXTRUSION TO CREATE A TIME-RELEASE DRUG  
Medical devices containing time release drug substance are disclosed, including medical tubing, catheters, stents, cables (including fiber optic cables), pills, capsules, sheaths, threads, clamps,...
US20120201876 METHOD OF MANAGING HYPERCORTISOLEMIA, HEADACHE DISORDERS, NEUROPATHIC PAIN AND RELATED DISORDERS  
The present disclosure relates to treatment and management of Cushing's syndrome, Headache disorders and Neuropathic using a composition comprising asiaticoside and madecasosside optionally along...
US20150024046 ABUSE-PROOFED ORAL DOSAGE FORM  
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, which...
US20140147499 ABUSE-PROOFED ORAL DOSAGE FORM  
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, which...
US20140017303 ACCORDION PILL COMPRISING LEVODOPA FOR AN IMPROVED TREATMENT OF PARKINSON'S DISEASE SYMPTOMS  
The invention provides for the use of an accordion pill comprising levodopa for the treatment of symptoms of Parkinson's disease in a subject in need thereof over a 24 hour period, to be...
US20150064242 TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF  
The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel, trialkyl, cationic lipids and nucleic acid-lipid...
US20110038927 CONTROLLED RELEASE HYDROCODONE FORMULATIONS  
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof,...
US20150132373 LYCOPENE AND RESVERATROL DIETARY SUPPLEMENT  
A dietary supplement is disclosed comprising lycopene and resveratrol in a range of ratio of lycopene:resveratrol from 1:10 to 10:1. Preferably, the ratio is 1:2 to 1:4. Lycopene is preferably of...
US20120121699 LYCOPENE AND RESVERATROL DIETARY SUPPLEMENT  
A dietary supplement is disclosed comprising lycopene and resveratrol in a range of ratio of lycopene:resveratrol from 1:10 to 10:1. Preferably, the ratio is 1:2 to 1:4. Lycopene is preferably of...
US20140199383 ABUSE RESISTANT OPIOID CONTAINING TRANSDERMAL SYSTEMS  
The present invention relates to transdermal dosage form (FIGS. 1-3) comprising at least one activating agent and at least one inactivating agent. The dosage form (FIGS. 1-3) releases the...
US20150017236 PHARMACEUTICAL COMPOSITIONS OF THYROID HORMONE  
Provided herein are methods of stabilizing thyroid hormone, preventing a thyroid hormone from being oxidized, producing a formulation of thyroid hormone having a uniform potency, and reducing the...
US20140302125 Methods for treating cardiovascular disorders  
There is provided a once-a-day therapeutically synergistic pharmaceutical dosage form for treatment of cardiovascular disorders, wherein the dosage form comprises a fixed dose combination of...
US20150174177 PROBIOTIC AND POLYPHENOL AGAINST NEURODEGENERATION  
The present invention relates to a composition comprising the probiotic strain Lactobacillus johnsonii CNCM I-1225 in combination with a polyphenol for use in the treatment or prevention of a...
US20150037263 TREATMENT OF MULTIPLE SCLEROSIS WITH COMBINATION OF LAQUINIMOD AND FINGOLIMOD  
This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the subject laquinimod as an...
US20140234407 Method for Increasing Lactose Tolerance in Mammals Exhibiting Lactose Intolerance  
The method for increasing lactose tolerance in subjects exhibiting lactose intolerance symptoms implements a protocol where the subjects ingest a gradually increasing amount of lactose containing...
US20130034601 METHOD FOR INCREASING LACTOSE TOLERANCE IN MAMMALS EXHIBITING LACTOSE INTOLERANCE  
The method for increasing lactose tolerance in subjects exhibiting lactose intolerance symptoms implements a protocol where the subjects ingest a gradually increasing amount of lactose containing...
US20110086093 METHOD FOR INCREASING LACTOSE TOLERANCE IN MAMMALS EXHIBITING LACTOSE INTOLERANCE  
The method for increasing lactose tolerance in subjects exhibiting lactose intolerance symptoms implements a protocol where the subjects ingest a gradually increasing amount of lactose containing...
US20140178466 Steroidal Compositions  
Provided herein are steroid containing composition suitable for providing therapeutically effective amount of at least one steroid to individuals. Also provided herein are compositions comprising...
US20130302396 Co-Delivery Of Stimulatory And Inhibitory Factors To Create Temporally Stable And Spatially Restricted Zones  
The invention provides methods and compositions for local manipulation of regenerative processes via exogenous factor delivery.
US20140193487 COMPOSITIONS AND METHODS FOR TREATING CENTRALLY MEDIATED NAUSEA AND VOMITING  
Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
US20110027353 Therapeutic Delivery System  
Therapeutic delivery systems are provided which, in a first embodiment, contain a plurality of multiphase capsules in which first and second therapeutic agents are contained in separate phases...
US20120021049 Single Daily Dosage Form for Prevention and Treatment of Metabolic Syndrome  
The present invention is in the fields of medicine, pharmaceuticals, nutraceuticals, endocrinology and cardiology. The invention provides compositions comprising a statin, an inhibitor of the...
US20150216930 CYSTINOSIN REPLACEMENT FACTOR  
The present invention provides compositions and methods for providing factor replacement therapy. In particular, the present invention provides replacement therapy for subjects suffering from...
US20140335166 Methods of Making and Using Nano Scale Particles  
A method for preparing a phospholipid delivery system encapsulating one or more bio-affecting compounds, includes the steps of solubilizing a heterogeneous phospholipid mixture into an organic...
US20120183606 DRUG DELIVERY SYSTEM COMPRISING POLYOXAZOLINE AND A BIOACTIVE AGENT  
The invention relates to drug delivery systems comprising a water-soluble polymer matrix and a bioactive agent entrained therein, said water soluble polymer matrix containing at least 50 wt. % of...
US20130156821 SOLID GANAXOLONE FORMULATIONS AND METHODS FOR THE MAKING AND USE THEREOF  
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about...
US20110311622 METHOD FOR ADDING SENSORY CONDITIONING CUES IN A PHARMACOTHERAPEUTIC REGIMEN  
A method for administering pharmaceutical agents to a subject is provided. The method includes the steps of: a) providing a course of treatment for a subject, which course includes periodically...
US20130302410 Neuroprotection in Demyelinating Diseases  
Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include secondary progressive multiple sclerosis and...
US20110305753 Treatment of celiac disease with IgA  
A process is provided for inhibiting symptoms of food allergy or food intolerance in a subject that includes the oral adminstration to the subject suffering from food allergy or food intolerance...
US20150157593 METHODS OF REDUCING LDL-P  
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing LDL-P comprising administering...
US20110212156 Use of a mixture of two or more enteric materials to regulate drug release via membrance or matrix for systemic therapeutics  
Disclosed are pharmaceutical compositions, particularly oral dosage forms, which comprise two or more enteric coating materials, either as a coating or as part of a matrix dosage form, and methods...
US20060188566 Nanoparticulate formulations of docetaxel and analogues thereof  
Described are nanoparticulate docetaxel or analogue thereof compositions. The compositions, which comprise a nanoparticulate docetaxel or analogue thereof and at least one surface stabilizer, can...
US20140056973 Oral Dosage Forms Having a High Loading of a Methyl Hydrogen Fumarate Prodrug  
Oral dosage forms and granulations with a high loading of a methyl hydrogen fumarate prodrug are disclosed.
US20150056274 COMPOSITIONS, METHODS AND KITS FOR REDUCING LIPID LEVELS  
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of nicotinic acid, nicotinamide riboside and/or...