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US20150140058 SKIN PRINTING AND AUTO-GRAFTING  
A holey substrate now is used for constructing a graft product, such as building an auto-graft by 3D printing of living cells. When the autograft built atop the holey substrate is implanted, blood...
US20130216601 THREE-DIMENSIONAL BONE IMPLANT AND METHOD FOR PRODUCING SAME  
A method for ex vivo production of a three-dimensional bone implant adapted for implantation to a patient, implants produced by such a method, and uses of such implants. The method comprises...
US20140277570 BONE GROWTH PROMOTION SYSTEMS AND METHODS  
This disclosure describes systems and methods for providing a novel delivery system for implantation in a patient. Further, this disclosure describes a delivery system including a carrier that is...
US20100310627 Xenotransplant for Stroke Therapy  
Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.
US20140205648 METHODS FOR THE IN SITU TREATMENT OF BONE CANCER  
The present invention relates to methods for in situ treatment of malignant cells from a cancer associated with bone. In one method, the treatment is for a primary cancer and entails positioning...
US20110142904 Methods for the In Situ Treatment of Bone Cancer  
The present invention relates to methods for in situ treatment of malignant cells from a cancer associated with bone. In one method, the treatment is for a primary cancer and entails positioning...
US20150246162 Biocompatible Implant  
A biocompatible implant is disclosed for use in a patient, comprising a biological material having an open microporous structure; and a biologically active compound. The biologically active...
US20110097367 MONOLITHIC IN-SITU CROSS-LINKED ALGINATE IMPLANTS  
A method of making and using a monolithic alginate implant is described. The implant is formed by providing an uncrosslinked, highly pure and high molecular weight alginate solution and injecting...
US20140105954 LAYERED SCAFFOLD SUITABLE FOR OSTEOCHONDRAL REPAIR  
The invention relates to a method for producing a multi-layer collagen scaffold. The method generally comprises the steps of: preparing a first suspension of collagen and freezing or lyophilising...
US20110086081 COATING SYSTEM AND METHOD FOR DRUG ELUTION MANAGEMENT  
The teachings are directed to a medical device having a drug-retaining coating that at least substantially delays the initial elution of a drug for a time effective at forming a functional...
US20150217022 NERVE REGENERATION EMPLOYING KERATIN BIOMATERIALS  
A keratin hydrogel matrix serves as an effective acellular scaffold for axonal regeneration and facilitates functional nerve recovery.
US20110137243 Coating On A Balloon Device  
The present invention provides a hygroscopic coating on a balloon for an implantable device and methods of making and using the same.
US20110129514 Hygroscopic coating on a balloon device  
The present invention provides a hygroscopic coating on a balloon for an implantable device and methods of making and using the same.
US20110196502 Methods of Using Water-Soluble Inorganic Compounds for Implants  
A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic...
US20110135704 Infection Control for Surgical and Trauma Patients  
Apparatus and methods for disrupting the colonization of Staphylococcus aureus are disclosed. A lysostaphin antimicrobial coating for bone implants and a lysostaphin gel for use on open wounds to...
US20110206754 IMPLANT DEVICE  
The present description relates to an implant device, having an improved integration in the tissue of the animal or human body into which it is inserted, when compared to the prior art devices....
US20110104228 SELF-ELIMINATING COATINGS  
The invention features the use of a matrix consisting of low molecular weight components for use as a self-eliminating coating for implantable medical devices. The matrix coatings can be used to...
US20110045050 NANOEMULSION FORMULATIONS FOR DIRECT DELIVERY  
A nanoemulsion and corresponding methods of making and using systems of single or blended high HLB value surfactant(s) for the emulsification of single or blended oils and vitamin E components in...
US20110076316 SCALABLE MATRIX FOR THE IN VIVO CULTIVATION OF BONE AND CARTILAGE  
The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue...
US20100303880 Tissue scaffolding comprising surface folds for tissue engineering  
The invention is directed to solid gradient scaffolds, methods of producing the same, and therapeutic applications arising from their utilization. Specifically, the gradient scaffolding includes,...
US20100121446 IMPLANT ASSEMBLY  
A implant assembly (1) includes a frame structure (10) with an inwardly protruding support flange (16), a first frame portion (12) extending above the flange (16) and a second frame portion (14)...
US20110256204 RAPID PREPARATION AND USE OF ENGINEERED TISSUE AND SCAFFOLDS AS INDIVIDUAL IMPLANTS  
Methods, technical apparatus and compositions to achieve short term processing for the manufacture of a graft or a transplant in the form of a scaffold that can be used to treat or to heal...
US20110059152 AUGMENTATION OF ORGAN FUNCTION  
The present invention provides methods and compositions for augmenting organ functions using small-scale matrix implants generated by seeding tissue-specific or undifferentiated cells onto a...
US20120093909 Ceramic Coatings and Applications Thereof  
In one aspect, the present invention provides coated metal substrates which, in some embodiments, demonstrate one or more advantageous chemical and/or mechanical properties.
US20150257987 INJECTABLE ALLOPLASTIC IMPLANTS AND METHODS OF USE THEREOF  
Described herein are injectable alloplastic implant compositions that are particularly useful for soft tissue defect augmentation. The compositions include microparticles, such as...
US20150217025 CROSSLINKER ENHANCED REPAIR OF KNEE MENISCUS  
A method of treating a tear in a knee meniscus of a patient. The method includes exposing the torn knee meniscus to a protein crosslinker during surgery to repair the tear. Also provided is a...
US20140205647 METHOD FOR TREATING DEFECTIVE DURA MATER  
Disclosed are an artificial dura mater and manufacturing method thereof. The artificial dura mater includes electrospun layers prepared by electrostatic spinning, at least one of which is a...
US20150086602 METHODS FOR COATING BONE ALLOGRAFTS WITH PERIOSTEUM-MIMETIC TISSUE ENGINEERING SCAFFOLDS  
Methods of coating bone surfaces and coated bones comprising a coating comprising (a) a porous polysaccharide scaffold and/or a plurality of polysaccharide nanofibers; and (b) a polyelectrolyte...
US20150238656 ORGAN/TISSUE DECELLULARIZATION, FRAMEWORK MAINTENANCE AND RECELLULARIZATION  
Methods for decellularizing organs and tissues in vitro and in vivo are provided, as are methods of maintaining organ and tissue frameworks and methods of recellularizing organs and tissues,...
US20100322994 PARTICULATE CARTILAGE SYSTEM  
The present invention is directed to compositions having at least one neocartilage particle, juvenile cartilage particle or a combination thereof and a matrix, and methods and devices that include...
US20140099353 METHOD FOR PRODUCING AN IMPLANT COATING, AND CORRESPONDING IMPLANT  
A medical implant which, on at least part of its surface, has a coating with an osteoinductive and/or osteoconductive top layer based on calcium phosphate and/or calcium carbonate, wherein an...
US20100255052 INTEGRATED IMPLANT SYSTEM (IIS) BIOCOMPATIBLE, BIODEGRADABLE AND BIOACTIVE, COMPRISING A BIOCOMPATIBLE STERILE POROUS POLYMERIC MATRIX AND A GEL, INTEGRATING IN SITU THE TRIDIMENSIONAL MATRIX STRUCTURE  
The present invention refers to an Integrated Implant System constituted as a gel-matrix-cells integrated system, that allows providing implants in a brief time period, for covering a great skin...
US20140271774 Coating For A Surface  
Coatings for a surface, especially a priming coating, of the present invention have been found to be durable, resistant to oxidative degradation, erosion and depolymerisation, stable to...
US20100172951 Enhanced Medical Implant  
A medical implant comprising in combination a synthetic, biological, or autologous matrix (or scaffold) and pluripotent stem cells derived from human teeth. Stem cells are harvested from the...
US20150125506 RETINAL PIGMENT EPITHELIAL CELLS DIFFERENTIATED FROM EMBRYONIC STEM CELLS WITH NICOTINAMIDE AND ACTIVIN A  
The present invention concerns RPE cells obtainable by directed differentiation from stem cell, particularly, human stem cells. It has been specifically found that culturing stem cells in the...
US20110027333 STEM CELL-DERIVED RETIN RETINAL PIGMENT EPITHELIAL CELLS  
The present invention concerns RPE cells obtainable by directed differentiation from stem cell, particularly, human stem cells. It has been specifically found that culturing stem cells in the...
US20150118278 LAMINAR CONSTRUCT FOR TISSUE-ENGINEERED DERMAL EQUIVALENT  
Compositions and methods for creating a laminar construct for tissue-engineered dermal equivalent are provided. One composition provided herein comprises a hydrogel matrix comprising two or more...
US20140271770 Methods And Compositions For Treating Post-Operative Pain Comprising Clonidine  
Effective implantable medical devices for reducing and treating post-operative pain are provided. The implantable medical device comprises clonidine in an amount from about 1 wt. % to about 30 wt....
US20140341964 COHESIVE OSTEOGENIC PUTTY AND MATERIALS THEREFOR  
Described is an implantable medical material comprising a malleable, cohesive, shape-retaining putty including mineral particles, insoluble collagen fibers and soluble collagen. The medical...
US20150056262 SOLID FORMS FOR TISSUE REPAIR  
This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
US20110318402 TRICALCIUM PHOSPHATES, THEIR COMPOSITES, IMPLANTS INCORPORATING THEM, AND METHODS FOR THEIR PRODUCTION  
Methods for the synthesis of tricalcium phosphates are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the tricalcium...
US20110117163 BIOACTIVE COATING FOR AN IMPLANTABLE DEVICE OR BIOPROSTHESIS  
For an implantable device intended for use in the human body an in-vivo colonization with autologous cells is often desired. The devices, especially prosthetic devices like implant tissues,...
US20140212468 PREPARATION METHOD OF AN IMPLANT COMPRISING DRUG DELIVERY LAYER AND IMPLANT COMPOSITION FOR LIVING DONOR TRANSPLANTATION COMPRISING THE SAME  
The present invention relates to a preparation method of implant comprising drug delivery layer and implant composition for living donor transplantation comprising the same, and more specifically,...
US20110117018 COMPOSITIONS AND METHODS FOR TREATING BONE  
The present invention relates to compositions, methods and kits for the treatment of bone particularly impaired or damaged bone.
US20120015331 SCAFFOLD  
The present invention provides a polymeric scaffold containing an antibacterial photoactive drug and optionally comprising seeded cells such as stem cells. The invention also includes methods of...
US20110123592 Biomaterials  
The invention relates to a biomaterial having a latent form of a growth factor immobilised thereon, and to a method of producing the biomaterial, comprising immobilising the latent form of the...
US20150190519 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPLASIA  
In accordance with the present invention, there are provided methods for treating hyperplasia in a subject in need thereof. In another aspect of the invention, there are provided methods for...
US20110064782 METHODS AND COMPOSITIONS FOR TISSUE REGENERATION  
A decellularised collagen-containing matrix for guided tissue regeneration, wherein the matrix is derived from a natural tissue material and is substantially free of non-fibrous tissue proteins,...
US20110009963 BIOCOMPATIBLE SCAFFOLD FOR LIGAMENT OR TENDON REPAIR  
A biocompatible ligament repair implant or scaffold device is provided for use in repairing a variety of ligament tissue injuries. The repair procedures may be conducted with ligament repair...
US20110076317 Rapid establishment and/or termination of substantial steady-state drug delivery  
The present invention is directed to treatment methods for a disease or condition, in a subject in need of such treatment, that provide alternatives to treatment by injection that give, relative...