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US20090297574 |
FLEXABLE SPIRALLY-ROLLED POLYMER TUBE FOR MONITORING AND TREATMENT OF BRAIN INJURIES
A flexible spirally-rolled polymer microtube for in vivo monitoring and treatment of brain injuries; the tube integrally comprising one or more microsensors and one or more microchannels, wherein...
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US20090297573 |
Identifying and Modulating Molecular Pathways that Mediate Nervous System Plasticity
The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in...
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US20090297572 |
Drug-Containing Implants And Methods of Use Thereof
The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides...
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US20090291120 |
Hydrophilic Polyurethane Compositions
A water-swellable linear polymer is made by reacting together a polyethylene oxide of number average molecular weight less than 4,000, an aliphatic diol, and a difunctional diisocyanate. Controlled...
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US20090285753 |
Novel haptotactic peptides
Novel cell attachment peptides having sequences homologous to specific portions of the carboxy terminal sequence of fibrinogen chains are disclosed. The novel peptides, derived from proteins...
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US20090274737 |
IMPLANT COMPRISING A SURFACE OF REDUCED THROMBOGENICITY
An implant for a human or animal body, comprising a surface having reduced thrombogenic properties, whose surface has a wetting angle of Θ, where Θ≦80°. Also disclosed is a method for...
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US20090274736 |
Nutraceutical Compositions From Microalgae And Related Methods of Production And Administration
Provided herein are polysaccharide compositions and methods of culturing microalgae to produce polysaccharides. Also provided are methods of using polysaccharides for applications such as reducing...
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US20090269383 |
MEDICAL DEVICES HAVING INORGANIC PARTICLE LAYERS
An expandable medical device having a particle layer disposed over a reservoir containing a therapeutic agent. The particle layer has a first porosity when the medical device is in the unexpanded...
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US20090263445 |
MEDICAL DEVICES COMPRISING SPRAY DRIED MICROPARTICLES
An implantable or insertable medical device which includes (a) a tacky polymeric region and (b) spray dried microparticles, which are adhered to the tacky polymeric region. The present invention is...
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US20090263444 |
Fluocinolone Formulations in a Biodegradable Polymer Carrier
Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation...
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US20090263443 |
METHODS FOR TREATING POST-OPERATIVE EFFECTS SUCH AS SPASTICITY AND SHIVERING WITH CLONDINE
Effective treatments of spasticity and shivering that accompanies surgeries are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relax...
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US20090263442 |
Post Biopsy Cavity Treatment Implants and Methods
A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix...
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US20090263441 |
DRUG DEPOTS HAVING DIFFREENT RELEASE PROFILES FOR REDUCING, PREVENTING OR TREATING PAIN AND INFLAMMATION
Effective treatments of pain and/or inflammation are provided. Through the administration of an effective amount of at least analgesic and/or at least one anti-inflammatory agent at or near a...
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US20090263319 |
METHODS AND COMPOSITIONS FOR TREATING POSTOPERATIVE PAIN COMPROSING KETOROLAC
Methods and compositions are provided for reducing, treating or preventing postoperative pain or inflammation in a patient in need of such treatment, the methods and compositions comprising...
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US20090258047 |
Heparin Prodrugs and Drug Delivery Stents Formed Therefrom
A prodrug comprising a heparin and a drug is provided. The prodrug can be used to form a coating on a medical device. The prodrug can also be used with a polymeric material to form a coating on a...
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US20090258046 |
COMPOSITION, FORMULATIONS AND KIT FOR TREATMENT OF RESPIRATORY AND LUNG DISEASE WITH NON-GLUCOCORTICOID STEROIDS AND/OR UBIQUINONE AND A BRONCHODILATING AGENT
A pharmaceutical or veterinary composition, which comprises a first active agent selected from a non-glucocorticoid steroid or analogues, a ubiquinone, or salts thereof, and a second active agent...
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US20090252780 |
COATINGS FOR IMPLANTABLE MEDICAL DEVICES
Coatings for implantable medical devices comprising non-fouling moieties or polymers chemically bonded to the surface of the device via chelating structures, and methods of fabricating the coatings...
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US20090246123 |
PHARMACEUTICAL GELS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS TO A SITE BENEATH THE SKIN
Pharmaceutical gels and methods for delivering a therapeutic agent to a target tissue site beneath the skin of a patient are provided, the gel being capable of adhering to the target tissue site...
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US20090238858 |
Compositions and Methods for Treating Ophthalmic Diseases
Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with...
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US20090238815 |
Nondegradable Hydrogels For Medical Device Application
Disclosed are nondegradable hydrogels used to coat or form at least a portion of a medical device. The hydrogels may be formed from functionalized PEG based macromers. These hydrogels are easy to...
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US20090232865 |
End-Capped Poly(Ester Amide) Copolymers
This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of...
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US20090232864 |
METHOD FOR APPLYING A BIOACTIVE, TISSUE-COMPATIBLE LAYER ONTO SHAPED ARTICLES AND THE USE OF SUCH SHAPED ARTICLES
A method for applying a bioactive, tissue-compatible layer onto a shaped article includes providing, as a target material, a bioactive glass ceramic having a S53P4 composition, cleaning a shaped...
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US20090232863 |
Biodegradable Carbon Diazeniumdiolate Based Nitric Oxide Donating Polymers
Disclosed herein are implantable medical devices coated with or comprising bioabsorbable carbon-based nitric oxide-donating polymers that upon exposure to physiological environments donate nitric...
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US20090226499 |
BIOCOMPATIBLE MATERIALS CONTAINING STABLE COMPLEXES OF TSG-6 AND HYALURONAN AND METHOD OF USING SAME
The present invention provides a biocompatible material in the form of a solid, a water insoluble cross-linked gel or a liposome, which contains a stable comples of TNF-stimulated gene protein...
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US20090215009 |
MEDICAL MATERIAL, ARTIFICIAL TOOTH ROOT, AND METHOD OF PRODUCING MEDICAL MATERIAL
[Problems] To provide a medical material having such a structure that enables even diffusion and distribution in the material of a sufficient amount a substance necessary for a medical treatment. ...
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US20090214612 |
EXTRACELLULAR TNF INHIBITORS FOR TREATING CNS DISORDERS
Methods and devices to attenuate tumor necrosis factor (TNF) and other pro-inflammatory mediators in the CNS to treat neurological, neurodegenerative, neuropsychiatric disorders, and brain injury...
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US20090214611 |
Implant Filling Material and Method
Compositions of cross-linked polyvinylpyrrolidone (PVP) are disclosed that are generally in the form of an elastic, hydrophilic, water-insoluble viscous cohesive mass of material that has many...
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US20090208551 |
Biological implantation material and method for preparing same
The present invention relates to a biological implantation material and method of preparing the same, which comprises the steps of: (i) treating a tissue derived from animal or human with alcohol;...
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US20090208550 |
Methods and compositions for treating hepatic diseases
The invention provides methods and compositions for treating a hepatic disease, for reducing fat deposition in the liver and for inhibiting fibrosis of the liver by administering a compound or...
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US20090208549 |
Devices and Methods for Reverse Lipid Transport
The present disclosure relates to devices methods for the reverse transport of lipids such as cholesterols for the treatment diseases and conditions caused by vulnerable plaques. The devices can...
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US20090202604 |
Benzodiazepine Formulation in a Polyorthoester Carrier
Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an...
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US20090196898 |
STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED
Bioimplants and methods of making the bioimplants are provided. The bioimplants comprise biological tissues having conjugated thereto adjunct molecules. The biological tissues are sterilized with a...
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US20090186070 |
Particle immobilized coating and uses thereof
Surface coatings including microparticles immobilized in a matrix of polymeric material on a substrate are described. The microparticles can also include an agent which can be useful for various...
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US20090186059 |
DEVICES AND METHODS FOR ELUTION OF NUCLEIC ACID DELIVERY COMPLEXES
Embodiments of the invention include devices and methods for the controlled elution of nucleic acid delivery complexes. In an embodiment, the invention includes a method of making a medical device....
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US20090175918 |
Ultra-Passivation of Chromium-Containing Alloy and Methods of Producing Same
The invention concerns article having a surface oxide layer up to 20 nm thick, the surface oxide layer comprising chromium and cobalt oxides where the atomic ratio of Cr/Co is more than 3. The...
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US20090169591 |
MEDICAL ARTICLES FOR THE TREATMENT OF TUMORS
In accordance with one aspect of the invention, implantable and insertable medical articles are provided which are useful for the local treatment of tumors. These medical articles comprise one or...
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US20090169472 |
METHODS AND COMPOSITIONS FOR TREATING IMMUNE DISORDERS
The present invention provides oligonucleotides, compositions comprising them and methods that use the oligonucleotides and compositions for stimulating cells expressing the TLR7 and/or TLR8...
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US20090162412 |
IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST
The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial....
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US20090162411 |
ENCAPSULATED KIDNEY TISSUE
Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said...
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US20090155331 |
INJECTABLE NANOPARTICULATE OLANZAPINE FORMULATIONS
Described are injectable formulations of particulate olanzapine that produce a prolonged duration of action upon administration, and methods of making and using such formulations. The injectable...
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US20090155330 |
Vaccine Delivery via Microneedle Arrays
A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have...
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US20090155326 |
LAYERED DRUG DELIVERY POLYMER MONOFILAMENT FIBERS
The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any...
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US20090148488 |
BIOACTIVE COATING FOR MEDICAL DEVICES
A medical device (and method for making same) comprising a passivating coating comprising keratin.
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US20090148487 |
MOLDABLE BIOMATERIAL FOR BONE REGENERATION
The present invention is directed to a moldable biomaterial comprising a particulate solid porous material and a biodegradable paste material. The paste material and the particulate solid porous...
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US20090148486 |
COMPOSITIONS AND METHODS FOR TREATING PULP INFLAMMATIONS CAUSED BY INFECTION OR TRAUMA
The present disclosed subject matter relates to methods and compositions for restoring a diseased or damaged tooth such that infection is inhibited or eliminated and pulp regeneration is...
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US20090148485 |
Controlled Release Devices and Structural Elements for Use in Their Manufacture
A structural element ( 2 ), suitable for use in the manufacture of a release device for intraruminal administration of an active agent to a ruminant animal, is of a compacted material, which...
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US20090142385 |
COMPOSITIONS FOR TREATING BONE DEFECTS
In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can...
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US20090136556 |
System And Method For Coating Implantable Devices
A method and system of coating an implantable device, such as a stent, are provided.
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US20090136554 |
Transdermal sustained release drug delivery
Provided herein are microprojections and microprojection arrays for delivering biologically active agents. Also provided herein are compositions suitable for coating such microprojections and...
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US20090136553 |
TRIGGERABLY DISSOLVABLE HOLLOW FIBERS FOR CONTROLLED DELIVERY
Provided are tubular structures of a biocompatible, triggerably-dissolvable material such as cellulose or a copolymer having an LCST below physiological temperatures. The structures may be embedded...
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