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US20110293723 |
SYNTHETIC NANOCARRIER COMBINATION VACCINES
Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are...
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US20110293701 |
MULTIVALENT SYNTHETIC NANOCARRIER VACCINES
The invention relates, at least in part, to compositions comprising populations of synthetic nanocarriers that comprise different sets of antigens as well as related methods.
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US20110293659 |
METHOD FOR THE ORAL/MUCOSAL VACCINATION BY MEANS OF RECOMBINANT YEASTS
Recombinant yeast cells are produced which are used for vaccination, among other uses for the oral vaccination by feeding.
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US20110110979 |
METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus...
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US20120141526 |
Nanoemulsion vaccines
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion...
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US20120003277 |
NANOEMULSION VACCINES
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more...
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US20130039958 |
METHOD OF VACCINATION
The present invention relates to improved methods for vaccination of a subject. Particularly, the present invention discloses the use of skin antigen application to amplify and improve a...
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US20110150940 |
DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION
This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said...
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US20120014995 |
PHARMACEUTICAL COMPOSITIONS AND METHODS TO VACCINATE AGAINST DISSEMINATED CANDIDIASIS AND OTHER INFECTIOUS AGENTS
The invention provides a vaccine including an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, with an adjuvant in a pharmaceutically acceptable...
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US20110150924 |
Device, Method, and system for neural modulation as vaccine adjuvant in a vertebrate subject
A method for enhancing an immune response in a vertebrate subject is described. The method includes providing at least one energy stimulus configured to modulate one or more nervous system...
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US20110206729 |
MUCOSAL VACCINE USING CATIONIC NANOGEL
A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of a...
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US20110165197 |
ADJUVANT COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE RESPONSES TO POLYNUCLEOTIDE-BASED VACCINES
The invention provides adjuvants, immunogenic compositions, and methods useful for polynucleotide-based vaccination and immune response. In particular, the invention provides an adjuvant of...
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US20110206755 |
METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION
The invention is based in part on the discovery that uncoupling proteins (UCPs) are expressed in the plasma membrane of rapidly dividing cells but not of growth arrested, chemotherapy resistant...
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US20120263753 |
BENZONAPHTHYRIDINE-CONTAINING VACCINES
The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) polymeric particles and (c) a benzonaphthyridine compound, which compositions elicits an immune...
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US20110243972 |
PROSTATE STEM CELL ANTIGEN VACCINES AND USES THEREOF
This invention relates to the identification of prostate stem cell antigen (PSCA) as a target of clinically relevant antitumor immune responses. The invention provides vaccines comprising PSCA, or...
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US20110243979 |
Method of Transcutaneous Immunization Using Antigen
Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system...
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US20110129494 |
Vaccine Formulations Comprising Saponin-containing Adjuvants
The present invention provides for a novel oil-in-water (O/W) emulsion, with increased stability in the presence of bacterial or viral suspensions, especially those concentrated and non-purified...
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US20110052638 |
ALLERGENS FROM ASPERGILLUS VERSICOLOR, AND METHOD OF DETECTING A MOLD ALLERGY CAUSED BY INTERIOR ROOMS
The invention relates to seven allergens of Aspergillus versicolor which are suitable for specific diagnostics of this mold which predominantly pollutes the interior. The invention is also directed...
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US20120201845 |
TRANSCUTANEOUS IMMUNIZATION WITHOUT HETEROLOGOUS ADJUVANT
Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system...
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US20120156287 |
Use of Vitelline Protein B as a Microencapsulating Additive
The present invention includes compositions and methods for the use of an encapsulation additive having between about 0.1 to about 30 percent isolated and purified vitelline protein B to provide...
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US20100297165 |
IMMUNOSTIMULATORY COMBINATIONS OF TLR LIGANDS AND METHODS OF USE
The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an immunostimulatory combination to a subject. In...
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US20110159042 |
PYTHIUM IMMUNOTHERAPY
A method and vaccine for modulating the immune system of animals with diseases other than caused by P. insidiosum, comprising administering to the animal immune modulating effective amount of the...
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US20120244182 |
USE OF TRYPTANTHRIN COMPOUNDS FOR IMMUNE POTENTIATION
The invention provides immunostimulatory compositions and methods of administration thereof. Also provided are methods of administering a tryptanthrin compound in an effective amount to enhance the...
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US20110135684 |
Use of L-alpha-lysophosphatidylcholine to obtain the differentiation of monocytes in mature dendritic cells in vitro
A method for treating and/or preventing certain ailments by administering to a person in need thereof L-α-lysophosphatidylcholine as an agent for activating the immune system of the person. Also, ...
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US20110045026 |
PRODUCTION OF FUNGAL EXTRACELLULAR IMMUNE STIMULATING COMPOUNDS
A process is described for the production of an immunostimulant by submerged cultivation of Lentinus edodes in which mycelium from agar plates or a fermentation broth is added to a liquid medium in...
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US20110171267 |
ANTI-FUNGAL COMPOSITION
A multivalent fungal vaccine comprising one or more heat-inactivated fungal antigens, wherein at least one fungal antigen is effective in producing an immune response in a host when said vaccine is...
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US20110262457 |
MODULATION OF THE IMMUNE RESPONSE
Methods for increasing the generation of IL-17-producing T cells (TH17) in vivo and in vitro, and enriched populations of TH17 cells for the treatment of diseases benefiting from an induced or...
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US20110206728 |
DNA VACCINES, USES FOR UNPROCESSED ROLLING CIRCLE AMPLIFICATION PRODUCT AND METHODS FOR MAKING THE SAME
A method of eliciting an immune response in an organism comprising: providing an unprocessed rolling circle amplification (RCA) product; and administering an effective amount of the unprocessed RCA...
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US20120258135 |
IMMUNOGENIC ANTI-INFLAMMATORY COMPOSITIONS
The invention provides methods of formulating an anti-inflammatory composition for treating inflammatory conditions in a specific organ or tissue. The method involves selecting at least one...
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US20120244181 |
CREATING BIOENGINEERED LYMPH NODES
The invention provides compositions and methods of treating various conditions, including tumors, with compositions comprising dendritic cells expressing exogenous chemokines.
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US20120328655 |
IMMUNOGENIC COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR INDUCING HUMORAL AND CELLULAR IMMUNE RESPONSES
Compositions and methods are provided herein for improved dual immunization strategies that induce in a subject an immune response that includes a humoral immune response and cellular immune...
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US20110111017 |
USE OF IMMUNOGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOGEN INFECTIONS
The invention provides compositions featuring cationic liposome nucleic acid molecules complexed with pathogen derived antigen and methods of using such compositions for the treatment or prevention...
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US20110177120 |
MYCOBACTERIUM TUBERCULOSIS VACCINE
The present invention relates to the use of live mycobacterium of the M. tuberculosis complex for preparing a medicament, wherein the function of the zmp1-gene is inactivated, pharmaceutical...
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US20120263754 |
Methods for Enhancing Immunogen Specific Immune Responses by Vectored Vaccines
Provided herein are methods for inducing a specific immune response in a subject by administering to the subject an immunogenic composition comprising a recombinant expression vector, or a vector...
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US20110195089 |
COMPOSITIONS, METHODS, AND KITS FOR ENHANCING THE IMMUNOGENICITY OF PATHOGENIC ANTIGENS
The invention provides a method of enhancing the immunogenicity of pathogenic antigens by removing or disrupting intrachain disulfide bonds responsible for maintaining tertiary protein structure....
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US20110287089 |
USE OF A SACCHAROMYCES CEREVISIAE MITOCHONDRIAL NUCLEIC ACIDS FRACTION FOR IMMUNE STIMULATION
The present invention relates to the use of a Saccharomyces cerevisiae mitochondrial nucleic acids fraction and an antigen for the preparation of a pharmaceutical composition intended to orient the...
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US20110268805 |
ADJUVANT INCORPORATION IN IMMUNONANOTHERAPEUTICS
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in...
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US20120192295 |
COMPOSITION COMPRISING EXTRACELLULAR MEMBRANE VESICLES DERIVED FROM INDOOR AIR, AND USE THEREOF
The present application relates to a composition comprising extracellular membrane vesicles derived from indoor air. In addition, the present application provides a method for diagnosing,...
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US20080003239 |
Yeast-based Vaccine for Inducing an Immune Response
The invention provided herein relates to vaccines that can be tailored to achieve a desired immune response. Some compositions provided herein are used for preferentially eliciting a humoral immune...
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US20110268763 |
POLYNUCLEOTIDES THAT STIMULATE NEUTROPHILS
The polynucleotides of the present invention are complementary to the Initiation Sites of microbes. Invading organisms, sensing the pH and nutrient deprivation of a physiologic environment quickly...
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US20100297176 |
Polyinosinic Acid - Polycytidylic Acid - Based Adjuvant
The present invention provides a polynucleotide adjuvant composition and methods of use in eliciting an immune response. The present invention also provides an immunogenic composition comprising...
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US20120321664 |
MODULATION OF YEAST-BASED IMMUNOTHERAPY PRODUCTS AND RESPONSES
Disclosed are methods to modulate yeast-based immunotherapy products and the immune responses, prophylactic responses, and/or therapeutic responses elicited by such products. Also disclosed are...
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US20120276136 |
CHEMICALLY PROGRAMMABLE IMMUNITY
The present invention is related to methods and compositions that are capable of immediately immunizing a human or animal against any molecule or compound. The present invention comprises an...
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US20110217244 |
COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE RESPONSE
The use of oxidatively transformed carotenoid or a component thereof to enhance the immune response in a subject for the treatment of infection or to enhance the immune response to an antigen in a...
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US20110104208 |
Enzyme Treatment of Glucans
β-(1-6)-Glucanese treatment of glucan from yeast cells, pure or feed grade, especially yeast from the family Saccharomyces and particularly Saccharomyces cerevisiae, provides a novel glucan ...
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US20120148594 |
MIMOTOPES OF HIV AND USES THEREOF
The invention provides methods, compositions and kits for treating and or preventing diseases having immunological components associated with their etiology and/or progression (e.g., an HIV...
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US20110280903 |
IMMUNOSTIMULATORY COMBINATIONS
The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also...
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US20110305667 |
USE OF A DEAD-BOX RNA HELICASE FOR INDUCING CYTOKINE PRODUCTION
The invention relates to the use of a DEAD-box RNA helicase from a yeast, a mammal, Leishmania infantum, or fragments thereof for inducing the production of cytokines by a peripheral blood...
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US20110212123 |
Immunogenic Substances Comprising a Polyinosinic Acid - Polycytidilic Acid Based Adjuvant
The present invention provides a polynucleotide adjuvant (PICKCa) composition and methods of use in eliciting an immune response, in particular a mucosal immune response. The polynucleotide...
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US20110182847 |
USE OF TLR AGONISTS AND/OR TYPE 1 INTERFERONS TO ALLEVIATE TOXICITY OF TNF-R AGONIST THERAPEUTIC REGIMENS
Improved (safer and more effective) methods of therapy using TNF-R agonists, e.g., CD40 agonists are provided. These methods provide for the addition of an amount of a type 1 interferon and/or a...
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