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US20110293723 SYNTHETIC NANOCARRIER COMBINATION VACCINES  
Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are...
US20140161836 CARIOUS TOOTH VACCINE AND PREPARATION METHOD  
The present invention provides a vaccine composition for dental caries caused by S. mutans infection, where the vaccine composition comprises an antigen derived from a surface protein PAc of S....
US20140205634 TREATMENT OF STREPTOCOCCAL INFECTIONS  
Methods of treating a Streptococcus pneumoniae infection are described herein.
US20140186399 PROTEIN MATRIX VACCINES AND METHODS OF MAKING AND ADMINISTERING SUCH VACCINES  
The invention relates to vaccine compositions having a carrier protein and an antigen of interest entrapped in a complex, methods of making such vaccines, and methods of vaccine administration.
US20140086989 Protein Matrix Vaccine Compositions Including Polycations  
The present invention relates to immunogenic compositions containing one or more antigens of interest, one or more carrier proteins, and one or more polycations, wherein the antigen of interest is...
US20110064723 Formulation for room temperature stabilization of a live attenuated bacterial vaccine  
This invention provides methods and compositions for stabilizing proteins and vaccines in dried formulations. In particular, a cavitation method and compositions of preparing a dried vaccine are...
US20140072622 VACCINE AGAINST STREPTOCOCCUS PNEUMONIAE  
The present invention relates to improved immunogenic compositions and vaccines, methods for making them and their use in medicine. In particular the invention relates to immunogenic compositions...
US20110110979 METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES  
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus...
US20110129501 VACCINE COMPRISING RECOMBINANT CLPP PROTEIN OF STREPTOCOCCUS PNEUMONIAE  
A method for immunizing a human or animal against pneumococcal infections, comprising by administering a vaccine comprising a purified recombinant caseinolytic protease P (ClpP) protein of S....
US20120100174 COMPOSITION COMPRISING SORTASE ANCHORED SURFACE PROTEINS OF STREPTOCOCCUS UBERIS  
The present invention provides an immunogenic composition comprising one or more Streptococcus uberis sortase-anchored surface proteins, or an immunogenic part thereof, wherein the composition is...
US20120328659 TREATMENT OF STREPTOCOCCAL INFECTIONS  
Immunogenic compositions and methods of treating a Streptococcus pneumoniae infection are described herein.
US20140099339 VACCINE AGAINST STREPTOCOCCUS PNEUMONIAE  
The present invention relates to a combination of 2 or more S pneumoniae proteins, their manufacture and use in medicine as a vaccine. Such combinations are particularly useful for the protection...
US20130243818 Composition Comprising Sortase Anchored Surface Proteins of Streptococcus Uberis  
The present invention provides an immunogenic composition comprising one or more Streptococcus uberis proteins, or an immunogenic part thereof, wherein the composition is capable of eliciting an...
US20120003277 NANOEMULSION VACCINES  
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more...
US20120231086 PROTEIN MATRIX VACCINES OF IMPROVED IMMUNOGENICITY  
The present invention relates to immunogenic compositions containing an antigen of interest entrapped with a crosslinked carrier protein matrix, methods of making such vaccines, and methods of...
US20140314812 LIVE, ATTENUATED STREPTOCOCCUS PNEUMONIAE STRAIN AND VACCINE FOR PROTECTION AGAINST PNEUMOCOCCAL DISEASE  
The present invention is an attenuated mutant strain of Streptococcus pneumonia that has a mutation in the FtsY gene. Vaccines, kits and methods for protecting a subject against Streptococcus...
US20100297184 Vaccines  
The invention provides Streptococcus vaccine strains (e.g. S. equi which is causative of ‘strangles’) comprising the following modifications in their genomes: (i) attenuation of one or more...
US20110091506 VACCINE COMPOSITIONS  
The present invention provides methods for the treatment or prevention of allergic airways diseases, the suppression of allergic immune responses, and the induction protective immunity against...
US20140004144 Attenuated Streptococcus suis Vaccines and Methods of Making and Use Thereof  
The present invention provides attenuated S. suis strains that elicit an immune response in animal S. suis, compositions comprising said strains, methods of vaccination against S. suis, and kits...
US20140193461 STREPTOCOCCUS VACCINE COMPOSITIONS AND METHODS OF USING THE SAME  
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides immunogenic nanoemulsion compositions and methods of...
US20120128719 STREPTOCOCCUS VACCINE COMPOSITIONS AND METHODS OF USING THE SAME  
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides immunogenic nanoemulsion compositions and methods of...
US20140044734 METHOD FOR TREATING LIVER INFLAMMATION, FIBROSIS AND NON-ALCOHOLIC STEATOHEPATITIS  
The invention is in the field of prevention and medical treatment of liver diseases, in particular non-alcoholic steatohepatitis (NASH). The invention provides means and methods for the treatment...
US20150231232 OUTER MEMBRANE VESICLES  
The present invention provides an outer membrane vesicle (OMV) from a Gram-negative bacterium, comprising at least one heterologous protein that is free in the lumen of the OMV, wherein the OMV is...
US20130039947 NOVEL IMMUNOGENS AND METHODS FOR DISCOVERY AND SCREENING THEREOF  
The present application is generally directed to methods for identifying immunogens from organisms and pathogens, and in particular for identifying immunogens which when administered as vaccines...
US20100297183 IMMUNOGENIC STREPTOCOCCUS PROTEINS  
The invention provides means and methods for identifying a Streptococcus protein which is capable of eliciting an immune response against at least two Streptococcus strains and/or serotypes. The...
US20120052088 PNEUMOCOCCAL VACCINE AND USES THEREOF  
The present invention relates to new pneumococcal vaccines. The invention also relates to vaccination of subjects, in particular immunocompromised subjects, against pneumococcal infections using...
US20130142825 METHOD OF PREVENTING AND TREATING INFLAMMATORY DISEASES AND DISORDERS WITH ABSCISIC ACID  
The present invention relates to the use of a therapeutically effective amount of abscisic acid (ABA) or its analogs to treat or prevent inflammation induced by exposure to lipopolysaccharide...
US20120034266 METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSE BY A NUTRACEUTICAL ANTIOXIDANT  
The present invention provides a new means of restoring the immune system in aging and immunocompromised individuals using an antioxidant nutraceutical. The nutraceutical stimulates the aging...
US20120244182 USE OF TRYPTANTHRIN COMPOUNDS FOR IMMUNE POTENTIATION  
The invention provides immunostimulatory compositions and methods of administration thereof. Also provided are methods of administering a tryptanthrin compound in an effective amount to enhance...
US20110110982 IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE  
The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to...
US20130004539 METHODS FOR PREVENTING AND TREATING STAPHYLOCOCCUS AUREUS COLONIZATION, INFECTION, AND DISEASE  
The invention provided herein relates to a method of preventing a Staphylococcus aureus colonization and/or infection by administering a Streptococcus pneumoniae strain, antigen thereof, or...
US20110311577 METHOD OF PRODUCING A VACCINE  
The present invention relates to a method for purifying bacterial cytolysins such as pneumococcal pneumolysin. A single chromatography step produces excellent purification of the cytolysin by...
US20120135037 FLAGELLIN FUSION PROTEINS AND CONJUGATES COMPRISING PNEUMOCOCCUS ANTIGENS AND METHODS OF USING THE SAME  
The present invention is based, in part, on flagellin adjuvant used to enhance immune responses directed against Streptococcus pneumoniae, in particular, to enhance immune responses to polypeptide...
US20150157702 PNEUMOCOCCAL SEROTYPE 6D  
Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6D, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal...
US20130315958 PNEUMOCOCCAL SEROTYPES  
Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal...
US20130216576 PNEUMOCOCCAL SEROTYPE 6D  
Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6D, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal...
US20110159040 NOVEL IMMUNOGENS AND METHODS FOR DISCOVERY AND SCREENING THEREOF  
An aspect of the present invention provides for methods for identifying novel immunogens that when administered as vaccines elicit a cellular or humoral immunogenic response. In a particular...
US20130216568 IMMUNOGENIC PROTEINS AND COMPOSITIONS  
The invention provides proteins and compositions for the treatment and prevention of Streptococcus agalactiae (Group B streptococcus; GBS).
US20130224244 VACCINE COMPOSITION FOR VACCINATING DOGS AGAINST CANINE INFECTIOUS RESPIRATORY DISEASE (CIRD)  
A vaccine composition for vaccinating dogs comprising any one or more of (a) an agent capable of raising an immune response against Streptococcus equi sub species zooepidemicus in a dog, (b) an...
US20110305688 NEW VIRULENCE FACTORS OF STREPTOCOCCUS PNEUMONIAE  
The present invention provides proteins/genes, which are essential for survival, and consequently, for virulence of Streptococcus pneumoniae in vivo, and thus are ideal vaccine candidates for a...
US20110159030 MUCOSAL COMBINATION VACCINES FOR BACTERIAL MENINGITIS  
A composition for mucosal delivery, comprising two or more of the following: (a) an antigen which induces an immune response against Haemophilus influenzae; (b) an antigen which induces an immune...
US20140294930 STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM  
In alternative embodiments, the invention provides vaccines, pharmaceutical compounds and formulations for diagnosing, preventing, treating or ameliorating Group A Streptococcus (GAS), Group C...
US20120258135 IMMUNOGENIC ANTI-INFLAMMATORY COMPOSITIONS  
The invention provides methods of formulating an anti-inflammatory composition for treating inflammatory conditions in a specific organ or tissue. The method involves selecting at least one...
US20110111017 USE OF IMMUNOGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOGEN INFECTIONS  
The invention provides compositions featuring cationic liposome nucleic acid molecules complexed with pathogen derived antigen and methods of using such compositions for the treatment or...
US20150153330 sAPP-alpha as a Biomarker for Prediction of Inflammatory and Autoimmune-Related Disorders  
The subject invention pertains to the use of amyloid precursor protein-alpha (sAPP-α) as a biomarker for prediction of a subject's risk of developing inflammatory and/or autoimmune-related...
US20120021003 VACCINE FOR PROTECTION AGAINST STREPTOCOCCUS SUIS BACTERIA OF VARIOUS SEROTYPES  
The present invention pertains to the use of Streptococcus suis antigens corresponding to Streptococcus suis bacteria of a predetermined serotype in the manufacture of a vaccine for administration...
US20120219586 ADJUVANTED VACCINE FORMULATIONS  
The invention relates to adjuvanted vaccine formulations, in particular influenza vaccines for intranasal delivery. Provided is an adjuvanted influenza vaccine formulation, comprising (i)...
US20120251577 SELECTIVELY DISRUPTED WHOLE-CELL VACCINE  
The present invention provides for immunogenic compositions and methods for producing an immunogenic composition with multiple immunity-inducing fractions of killed, whole-cell Streptococcus...
US20120276130 DIAGNOSTIC AND THERAPEUTIC METHODS FOR RHEUMATIC HEART DISEASE BASED UPON GROUP A STREPTOCOCCUS MARKERS  
This invention is in the field of identifying patients having rheumatic heart disease (RHD) associated with Streptococcus pyogenes (Group A Streptococcus; GAS) infection and identifying patients...
US20110217329 Vaccine  
The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to vaccines comprising a pneumococcal polysaccharide antigen,...
Matches 1 - 50 out of 193 1 2 3 4 >