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US20140314811 HERPES SIMPLEX VIRUS VACCINES  
The present invention is directed to Herpes simplex-2 viruses that may be used in vaccines to immunize patients against genital herpes.
US20110177125 HSV-1 AND HSV-2 VACCINES AND METHODS OF USE THEREOF  
This invention provides methods of vaccinating a subject against a Herpes Simplex Virus (HSV) infection and disorders and symptoms associated with same, and impeding, inhibiting, reducing the...
US20140193460 HERPES VIRUS VACCINE AND METHODS OF USE  
Provided herein are, inter alia, vaccines and methods of using the same for the treatment or prevention of Herpesvirus infections.
US20110256176 HERPES SIMPLEX VIRUS COMBINED SUBUNIT VACCINES AND METHODS OF USE THEREOF  
This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune...
US20130202639 Synthetic Herpes Simplex Viruses for Treatment of Cancers  
New recombinant oncolytic viral vectors have been constructed based on a known herpes simplex virus-1 with a single 34.5 gene and a synctial mutation (called OncSyn (OS) virus), which was designed...
US20130045180 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20120195852 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20120114695 HSV-1 AND HSV-2 VACCINES AND METHODS OF USE THEREOF  
This invention provides methods of treating, suppressing, inhibiting, reducing an incidence, reducing the pathogenesis of, ameliorating the symptoms of, or ameliorating the secondary symptoms of a...
US20130052235 HERPES SIMPLEX VIRUS NANOEMULSION VACCINE  
The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from...
US20110135685 Edible Vaccines Expressed in Soybeans  
The present invention relates to vaccines that are made in transgenic soybeans for use in humans, animals of agricultural importance, pets, and wildlife. These vaccines are used as vaccines...
US20120003277 NANOEMULSION VACCINES  
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more...
US20110014274 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT  
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant...
US20150037367 Methods and Compositions Of Protein Antigens For The Diagnosis And Treatment of Herpes Simplex Viruses Type 1 and 2  
Contemplated compositions, devices, and methods are drawn to various antigens from Herpes Simplex Virus type 1 (HSV-1) and Herpes Simplex Virus type 2 (HSV-2) and their use in vaccines,...
US20120027841 NOVEL MUCOSAL VACCINATION APPROACH FOR HERPES SIMPLEX VIRUS TYPE-2  
The invention provides methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. The protective immune response elicited by the methods...
US20140363469 VIRAL ATTENUATION AND VACCINE PRODUCTION  
The present invention is directed to the generation of attenuated viruses or viral transcripts for the production of vaccines by incorporating microRNA binding sites within the viral target...
US20130034586 AVIRULENT ONCOLYTIC HERPES SIMPLEX VIRUS STRAINS ENGINEERED TO COUNTER THE INNATE HOST RESPONSE  
The present invention relates to an avirulent, oncolytic herpes simplex virus modified from a wild-type herpes simplex virus so that both γ134.5 genes of the virus have been deleted and each...
US20120244182 USE OF TRYPTANTHRIN COMPOUNDS FOR IMMUNE POTENTIATION  
The invention provides immunostimulatory compositions and methods of administration thereof. Also provided are methods of administering a tryptanthrin compound in an effective amount to enhance...
US20130273108 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20130273107 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20130202640 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20120328658 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20120328657 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20120328656 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20150147355 Compositions and Methods of Vaccination  
The present invention relates to a vaccination strategy that establishes protective immunity, including a protective memory T-cell population.
US20150030631 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to therapeutic compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong...
US20150010596 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to therapeutic compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong...
US20150056181 NANOCARRIERS WITH MULTI-PHOTON RESPONSE ELEMENTS  
Compositions are provided in which dendrimers and/or nanoparticles are synthesized with multi-photon responsive elements and self-immolative oligomers. The compositions may be utilized to...
US20120328655 IMMUNOGENIC COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR INDUCING HUMORAL AND CELLULAR IMMUNE RESPONSES  
Compositions and methods are provided herein for improved dual immunization strategies that induce in a subject an immune response that includes a humoral immune response and cellular immune...
US20110059134 PREVENTION OF RECURRENT VIRAL DISEASE  
The present invention discloses compositions and methods for ameliorating or reducing recurrent viral disease, which compositions and methods result in an increase in virus specific immunoglobulin...
US20130189294 RAPID, EFFICIENT PURIFICATION OF HSV-SPECIFIC T-LYMPHOCYTES AND HSV ANTIGENS IDENTIFIED VIA SAME  
Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are...
US20130011425 RAPID, EFFICIENT PURIFICATION OF HSV-SPECIFIC T-LYMPHOCYTES AND HSV ANTIGENS IDENTIFIED VIA SAME  
Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are...
US20110135687 RAPID, EFFICIENT PURIFICATION OF HSV-SPECIFIC T-LYMPHOCYTES AND HSV ANTIGENS IDENTIFIED VIA SAME  
Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are...
US20150010597 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response...
US20140370055 COMPOSITIONS AND METHODS FOR VACCINATING AGAINST HSV-2  
This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response...
US20120045430 DENDRIMER-LIKE MODULAR DELIVERY VECTOR  
Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. The nucleic...
US20100055132 NON-SPECIFIC DELAYED-TYPE HYPERSENSITIVITY RESPONSE TO TREAT HERPES SIMPLEX VIRUS INFECTION  
A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient...
US20110033499 ANTI-VIRAL NUTRACEUTICAL  
A method for the prophylaxis or treatment of a viral infection in a mammal is described. The method comprises administering to the mammal an effective amount of a mollusc hemocyanin and/or an...
US20120171244 MUCOSAL BOOSTING FOLLOWING PARENTERAL PRIMING  
Mucosal immunization using one or more antigens following parenteral administration of the same or different antigens is described.
US20120251537 COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFECTIONS AND TUMORS  
PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced...
US20070207169 EARLY CHILDHOOD INFECTION WITH HUMAN HERPES VIRUS TYPE 6 (HHV-6) AS A PROTECTION AGAINST THE DEVELOPMENT OF IGE SENSITIZATION, ATOPIC DISEASE AND ALLERGY IN YOUNG CHILDREN  
The present invention discloses a use of human herpes virus 6 (HHV-6) or derivatives thereof, for the manufacture of a pharmaceutical composition intended to be administered during early...
US20130309262 HSV-1 EPITOPES AND METHODS FOR USING SAME  
The invention provides HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection. T-cells having specificity for antigens of the invention have demonstrated...
US20110135679 COMPOSITIONS FOR INDUCING IMMUNE RESPONSES  
The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) at least first and second adjuvants, wherein the first adjuvant comprises microparticles and...
US20140093537 IMMUNOGENIC COMPOSITIONS COMPRISING NANOEMULSION AND METHODS OF ADMINISTERING THE SAME  
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides immunogenic nanoemulsion compositions and methods of...
US20080089910 Attenuated Herpes Simplex Virus Type-2, Vectors Thereof and Immunogenic Compositions Thereof  
The present invention broadly relates to the attenuation of herpes simplex virus type 2 (HSV-2). More particularly, the invention relates to the identification of mutations in the HSV-2 UL24 gene...
US20150071965 VIRAL VECTORS AND THEIR USE IN THERAPEUTIC METHODS  
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
US20130280299 VIRAL VECTORS AND THEIR USE IN THERAPEUTIC METHODS  
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
US20100330101 BIFUNCTIONAL CpG OR OLIGO-/POLYNUCLEOTIDE AND TOXIN OR ENTEROTOXIN CONTAINING COMPOSITION  
A bifunctional composition comprising an intracellularly effective immunomodulating nucleic acid component containing at least one immunostimulatory, immunoinhibitory or immunomodulating motif and...
US20120027790 IMMUNOLOGICAL HERPES SIMPLEX VIRUS ANTIGENS AND METHODS FOR USE THEREOF  
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by...
US20150004195 PURIFICATION OF HERPES VIRUS  
The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion ex change chromatography and tangential flow filtration.
US20070298093 Synergistic Liposomal Adjuvants  
The present invention relates to liposome, mixtures or liposomes and liposomal compositions comprising at least two different adjuvants and a therapeutic agent, their production and use for the...

Matches 1 - 50 out of 93 1 2 >