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US20090202638 |
BMP GENE AND FUSION PROTEIN
This invention relates to BMP fusion genes, BMP fusion proteins, and methods for making BMP fusion genes and BMP fusion proteins. The invention further relates to methods for treatment using BMP...
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US20080181906 |
Polyvalent Immunogen
The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for...
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US20080181885 |
NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 202P5A5 USEFUL IN TREATMENT AND DETECTION OF CANCER
A novel gene 202P5A5 and its encoded protein, and variants thereof, are described wherein 202P5A5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
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US20080112940 |
Notch2 signaling as a breast cancer suppressor pathway
The present invention relates to the ability of constitutively active Notch 2 to function as an inhibitor of breast cancer. The invention provides methods and compositions for inhibiting breast...
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US20080107670 |
METHOD OF PRODUCING AN HIV-1 IMMUNE RESPONSE
The present invention comprises novel and modified peptides capable of inducing an HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective...
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US20080107669 |
METHOD OF PRODUCING AN HIV-1 IMMUNE RESPONSE
The present invention comprises novel and modified peptides capable of inducing an HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective...
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US20080107668 |
CYTOTOXIC T-LYMPHOCYTE-INDUCING IMMUNOGENS FOR PREVENTION, TREATMENT, AND DIAGNOSIS OF CANCER
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as breast carcinoma. The invention discloses peptides,...
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US20080107667 |
PROMISCUOUS HER-2/NEU CD4 T CELL EPITOPES
The present invention relates to the discovery of novel T cell epitopes of the human HER-2/Neu protein that is promiscuous for at least 25 different HLA-DR alleles. The invention also relates to...
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US20080107666 |
Non-Glycosylated Recombinant Collagen-Like Polypeptides
The invention relates to recombinant collagen like polypeptides that are not glycosylated thereby reducing the immunogenicity of recombinant collagen-like polypeptides while at the same time...
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US20080107597 |
ISOLATION OF ANTIBODIES THAT CROSS-REACT AND NEUTRALIZE RANKL ORIGINATING FROM MULTIPLE SPECIES
The invention provides specific binding members (e.g., antibodies or antigen-binding fragments thereof) which bind to RANKL originating from multiple species. An epitope recognized by the specific...
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US20080095790 |
Methods of Treating Prostate Cancer
A method of treating prostate cancer in a human using a prostate-specific antigen peptide vaccine and a dosing regimen for administering said vaccine is provided.
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US20080085286 |
ASPERGILLUS VACCINE PREPARATION AND METHODS OF MAKING AND USING THEREOF
The present invention relates to compositions and methods in preventing and/or treating diseases caused by Aspergillus . In particular, the present invention is directed to Aspergillus vaccine...
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US20080081043 |
NK cell activation inducing ligand (NAIL) DNA and polypeptides, and use thereof
The invention is directed to purified and isolated novel NAIL polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides,...
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US20080063654 |
Prostate Cancer Vaccine
Androgen receptor-based vaccines for eliciting an immune reaction in vivo against cells expressing androgen receptor are disclosed. The vaccines are useful in the treatment of prostate cancer. Also...
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US20080057076 |
Novel fibroblast growth factors
Novel nucleic acids, polypeptide sequences, and nucleic acid regulators thereof, have been identified which code for a fibroblast growth factor (FGF), preferably FGF-20 or FGF-23, a class of...
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US20080057065 |
Phep, an Amino Acid Permease of Staphylococcus Aureus
The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. 1, vaccines comprising the...
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US20080044418 |
Tumor Antigens and Uses Thereof
The invention features tumor antigens; tumor antigen-encoding nucleic acids; antibodies specific for tumor antigens and methods of using the antibodies; methods of identifying tumor antigens and...
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US20080038287 |
Method For Identification, Isolation and Production of Antigens to a Specific Pathogen
Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to autoimmunity,...
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US20080038286 |
Glycosylated polypeptides produced in yeast mutants and methods of use thereof
The invention provides various high mannose glycosylated polypeptides that are useful in a vaccine formulations. The invention also provides methods for making such glycosylated polypeptides and...
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US20080038285 |
Method for Identifying and Quantifying of Tumour-Associated
Described is a method for identifying and quantifying of tumour-associated peptides, wherein first at least two different sources for obtaining the peptide are provided (tumourous and healthy...
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US20080031888 |
Tumor antigens
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US20080019993 |
Inhibition of tumour growth
The present invention provides a cytotoxic 7 to 25 mer peptide with three or more cationic residues which has one or more non-genetic bulky and lipophilic amino acids, as well as esters, amides,...
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US20080019992 |
Antigen mimotopes and vaccine against cancerous diseases
The present invention relates to a vaccine against cancerous diseases and antigen mimotopes associated with the high molecular weight melanoma associated antigen (HMW-MAA). The vaccines and antigen...
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US20080019991 |
Carrier Conjugates Of Tnf-Peptides
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a modified virus-like particle (VLP) comprising a VLP and a particular...
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US20080014211 |
Methods to elicit, enhance and sustain immune responses against MHC class I-restricted epitopes, for prophylactic and therapeutic purposes
Embodiments of the present invention relate to methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to...
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US20080014210 |
PEPTIDES AND ANTIBODIES TO MUC 1 PROTEINS
The invention relates to methods of inhibiting proliferation or growth of tumor cells and/or inducing cell death in cancer cells. This invention relates to the use of antibodies, hybridomas and...
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