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US20150071990 Method of Treating Patients with a Mucinous Glycoprotein (MUC-1) Vaccine  
The present invention provides a method for treating an individual who is afflicted with a cancer, such as non-small cell lung cancer or prostate cancer, by administering to that individual a...
US20130315857 Kexin-Derived Vaccines to Prevent or Treat Fungal Infections  
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
US20130058891 Kexin-Derived Vaccines to Prevent or Treat Fungal Infections  
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
US20150118259 28 KDA GST PROTEINS FROM SCHISTOSOMA FOR THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY AUTOIMMUNE DISEASES GENERATING A TH1 AND/OR TH17 RESPONSE  
The present invention relates to a product selected from a protein, a fragment of the protein, a derived sequence and a homologous sequence of the protein, the protein including or being...
US20150246090 NON-DIGESTIBLE OLIGOSACCHARIDES FOR ORAL INDUCTION OF TOLERANCE AGAINST DIETARY PROTEINS  
Compositions and methods for providing infant nutrition with partially hydrolysed proteins and non-digestible oligosaccharides for use in induction of oral tolerance against native dietary proteins.
US20100297158 ANTICANCER VACCINE AND DIAGNOSTIC METHODS AND REAGENTS  
The invention provides a method for vaccinating a patient against a malignancy comprising introducing a protein or peptide comprising of all or an immunogenic fragment of a cyclin protein into the...
US20110076323 VACCINE FOR ALZHEIMER'S DISEASE  
Compositions and methods for prevention and treatment of Alzheimer's disease utilize a combination of amyloid-beta protein or a fragment thereof and a heat shock protein or a fragment thereof.
US20130064828 Chimeric Vaccine for Haemophilus Influenzae-Induced Disease  
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention...
US20110243975 TRANSFORMED SOYBEAN PLANT WHICH ACCUMULATES VACCINE, AND USE THEREOF  
A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s)...
US20150064240 MUC1 Based Glycolipopeptide Vaccine with Adjuvant  
Provided herein are liposomal glycolipopeptidic vaccine formulations comprising an adjuvant and an immunogen for immunotherapy and/or treatment of cancer.
US20120282329 MUC1 Based Glycolipopeptide Vaccine with Adjuvant  
Provided herein are liposomal glycolipopeptidic vaccine formulations comprising an adjuvant and an immunogen for immunotherapy and/or treatment of cancer.
US20120219617 MUC1 Based Glycolipopeptide Vaccine with Adjuvant  
Provided herein are liposomal glycolipopeptidic vaccine formulations comprising an adjuvant and an immunogen for immunotherapy and/or treatment of cancer.
US20110027267 Fusion Proteins of Mannose Binding Lectins for Treatment of Disease  
Fusion proteins having sequences that target specific moieties such as carbohydrates, lipids, and/or proteins that are associated with certain cell types and/or pathogens; and a sequence that...
US20130095127 METHODS OF INHIBITING INFLAMMATION AND INFLAMMATORY DISEASES USING Gal-3BP (BTBD17B, LGALS3BP, GALECTIN-3 BINDING PROTEIN, MAC-2 BINDING PROTEIN)  
The invention provides Galectin-3 binding protein (Gal-3BP, BTBD17B) polypeptides, Gal-3BP compositions, and methods of use, and uses, for example, in treatment, diagnostic, detection and...
US20130142817 MICROBIAL DELIVERY SYSTEM  
The present invention provides methods and compositions for treating or preventing allergic responses, particularly anaphylactic allergic responses, in subjects who are allergic to allergens or...
US20110027298 MICROBIAL DELIVERY SYSTEM  
The present invention provides methods and compositions for treating or preventing allergic responses, particularly anaphylactic allergic responses, in subjects who are allergic to allergens or...
US20150044243 MUCOSAL IMMUNIZATION TO PREVENT PRION INFECTION  
Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a...
US20140286972 HYPOALLERGENIC CHIMERIC PROTEINS BELONGING TO THE LIPID TRANSFER FAMILY OF PARIETARIA JUDAICA FOR USE IN THE TREATMENT OF ALLERGIES  
The present invention relates to recombinant DNA molecules which encode chimeric polypeptides of differing allergens of Parietaria judaica which can be used for the prevention and treatment of...
US20130189289 VACCINE FOR TREATMENT OF TAUTOPATHY  
This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a...
US20110311518 NOVEL SYNTHETIC AGONISTS OF TLR9  
The invention relates to synthetic chemical compositions that are useful for modulation of Toll-Like Receptor (TLR)-mediated immune responses. In particular, the invention relates to agonists of...
US20130330368 EYE DROP COMPOSITION FOR PREVENTION AND TREATMENT OF OPHTHALMIC DISEASES CONTAINING FUSION PROTEIN OF FK506 BINDING PROTEIN  
Disclosed is a treatment for ophthalmic diseases, more specifically, a pharmaceutical composition for treating ophthalmic diseases including a fusion protein of FK506 binding protein capable of...
US20150238583 DNA Vaccines Encoding Heat Shock Proteins  
A method of treating a T cell-mediated inflammatory autoimmune disease by administering to an individual in need thereof an immunogenic composition comprising a recombinant construct of a nucleic...
US20130122083 DNA VACCINES ENCODING HEAT SHOCK PROTEINS  
A method of treating a T cell-mediated inflammatory autoimmune disease by administering to an individual in need thereof an immunogenic composition comprising a recombinant construct of a nucleic...
US20110091493 VACCINE COMPOSITIONS AND USES THEREOF  
The present invention relates to vaccine compositions and uses thereof. Embodiments of the present invention provide oral bacterial (e.g., probiotic lactic acid bacteria) vaccine delivery systems...
US20120100102 CANCER VACCINE  
We disclose a vaccine comprising a pappalysin and vaccine compositions comprising a pappalysin.
US20130309273 Thermostable Vaccine Compositions and Methods of Preparing Same  
The disclosure provides compositions relating to thermostable vaccines and methods of preparing same. Specifically, the disclosure provides for methods of preparing thermostable vaccines based on...
US20140227304 VACCINES FOR PREVENTING AND TREATING ALZHEIMER'S DISEASE  
Disclosed herein are vaccines comprising an amyloid beta antigen and a nucleic acid encoding the amyloid beta antigen, or a variant thereof. T cell proliferation can be inhibited and iTreg cells...
US20140356368 APPLICATIONS OF AN IMMUNE SYSTEM-RELEASED ACTIVATING AGENT (ISRAA)  
The present invention relates to applications of an immune system-released activating agent (ISRAA) polypeptide, which is induced by a nervous stimulus and which has been found to mediate the...
US20150033410 METHODS AND COMPOSITIONS FOR EMERGENCY POST-INFECTION TREATMENT OF ANTHRAX  
Compositions effective for treating or preventing an anthrax infection in a subject in need thereof and recombinant proteins included in the compositions are provided. Methods for producing...
US20110256164 VACCINE FOR THE PREVENTION OF BREAST CANCER RECURRENCE  
Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER/neu oncogene, GP2, with the effect of inducing and maintaining protective or...
US20120100165 DRUG TRANSPORTER, AND ADJUVANT AND VACCINE EACH UTILIZING SAME  
An objective of the invention is to provide a drug delivery vehicle capable of allowing a vaccine or adjuvant to reach a target cell or tissue efficiently while being capable of improving the...
US20130183328 CANCER VACCINES AND VACCINATION METHODS  
Methods and compositions for treating cancers (e.g., neural cancers) by dendritic cell vaccination are provided herein.
US20120156232 CANCER VACCINES AND VACCINATION METHODS  
Methods and compositions for treating cancers (e.g., neural cancers) by dendritic cell vaccination are provided herein.
US20110078828 MULTI EPITOPE VACCINE FOR POULTRY  
Antigenic polypeptides, capable of inducing an immune response against multiple parasites, and methods of designing such polypeptides, are provided. Also provided by the invention are...
US20130236418 Immunomodulatory Methods and Systems for Treatment and/or Prevention of Aneurysms  
Immunomodulatory agents, T cell, compositions, methods and systems for treating and/or preventing an aneurysm and/or a condition associated thereto in an individual.
US20150182609 VACCINE FOR THE PREVENTION OF BREAST CANCER RELAPSE  
The invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75, with the effect of inducing and maintaining...
US20130189290 VACCINE FOR THE PREVENTION OF BREAST CANCER RELAPSE  
The invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75, with the effect of inducing and maintaining...
US20140294875 Leishmania Vaccine Using Sand Fly Salivary Immunogen  
The present invention provides vectors that contain and express in vivo or in vitro sand fly Lu. longipalpis salivary antigens that elicit an immune response in animal or human against Leishmania,...
US20140178418 Breast Cancer Vaccine  
Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin.
US20120003254 Breast Cancer Vaccine  
Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin.
US20150079119 IDENTIFICATION AND USE OF NOVOPEPTIDES FOR THE TREATMENT OF CANCER  
Compositions, methods, systems, apparatus and/or articles of manufacture are disclosed for reducing the susceptibility of a population and/or members thereof to cancer, which may include...
US20140234350 OVARIAN CANCER VACCINES AND VACCINATION METHODS  
Compositions of multipeptide vaccines including tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from tumor associated...
US20120030780 TARGETING OF SALL4 FOR THE TREATMENT AND DIAGNOSIS OF PROLIFERATIVE DISORDERS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME (MDS)  
The present invention discloses nucleic acids, proteins, and antibodies for SALL4 (including isoforms SALL4A, SALL4B, and SALL4C), a zinc finger transcriptional factor. Further, methods are...
US20140234351 CANCER VACCINES AND VACCINATION METHODS  
Compositions of multipeptide vaccines comprising at least seven tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from at...
US20150250863 Method for Eliciting an Immune Response to Human Telomerase Reverse Transcriptase  
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of...
US20110229503 Vaccination against malignant melanoma using bcg and/or vaccinia  
The present invention relates to a vaccination which reduces the risk to contract melanoma to about half to third and moreover, within a five year period post diagnosis of malignant melanoma the...
US20110256064 Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins  
The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and...
US20140370039 IL-12 IMMUNOTHERAPY FOR CANCER  
Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery...
US20100297160 High Molecular Weight Amyloid Beta As a Carrier for the Oral Delivery of Vaccine Antigens  
Compositions and methods are provided for stabilizing polypeptide antigens such as amyloid-beta (Aβ) to produce vaccines for oral delivery. One embodiment provides an immunogenic polypeptide...
US20130224233 IMMUNOTHERAPEUTIC METHOD FOR TREATING PROSTATE CANCER  
The invention relates to treatment of prostate cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a portion of a prostatic...