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US20110081357 Chimeric Vaccine for Haemophilus Influenzae-Induced Disease  
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention...
US20150197766 METHODS AND COMPOSITIONS FOR PRODUCTION OF RECOMBINANT PHARMACEUTICAL PROTEINS IN MEDICINAL PLANTS  
Methods of tissue culture and in vitro propagation of medicinal plants, in particular, plants of the genera Hydrastis, Echinacea, Kalanhoe, Thymus and Calendula are described. Methods of...
US20130004510 VACCINE  
Compositions and methods for the treatment or prevention of Gram-negative bacterial strain infection are provided herein. Methods for the manufacture of said compositions are also provided herein.
US20140010824 Methods, compositions and kits for treating or preventing a disease associated with Gram-negative bacteria  
Compositions, methods and kits are provided for identifying at least one virulence factor of a Gram-negative bacterial strain, and for preparing attenuated bacterial strain vaccines or a modulator...
US20140050741 SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS  
The present invention relates to synthetic lipoteicoic acid (LTA) mimetics which are useful as vaccine components for therapy and/or prophylaxis of bacterial infection.
US20120177650 THERAPY FOR ENTERIC INFECTIONS  
A method and composition for treating enteric pathogen infections in animals suffering from such infections or displaying diseases or conditions consistent with such infections or for preventing...
US20150086542 COMPOSITIONS AND METHODS FOR THE PREVENTION OF MICROBIAL INFECTIONS  
This disclosure provides methods and compositions to inhibit or prevent infection of a cell by a bacteria that exports DNABII proteins by administering to a tissue infected with the bacteria an...
US20110014210 CHLAMYDIA VACCINE  
Compositions and methods for the treatment of Chlamydial infection are disclosed. The compositions provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen...
US20110027280 Methods For Inducing Autolysis In Infectious Bacteria  
The present invention relates to methods for the killing of infectious bacteria by modulating the extra-cellular concentration of bacterial cell signalling molecules. This has the effect of...
US20130058953 CHARACTERIZATION OF THE CBIR1 ANTIGENIC RESPONSE FOR DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE  
This invention provides methods of diagnosing or predicting susceptibility to Crohn's Disease by determining the presence or absence of genetic variants. In one embodiment, the present invention...
US20100303830 PREVENTION AND TREATMENT OF OTITIS MEDIA USING IgA ENRICHED MILK  
This invention relates to a composition suitable for use in the prevention or treatment of otitis media comprising IgA derived from mature bovine milk and having specificity for at least one of...
US20130052204 (POLY)-GLYCEROLPHOSPHATE-BASED ANTI-GRAM POSITIVE BACTERIAL VACCINE  
Provided are an immunogenic composition comprising polyglycerol phosphate (PGP) and methods for using the composition for treating or preventing staphylococcal infections. The PGP may be...
US20130195892 BVDV VACCINE  
The present invention relates to BVD virus and to its uses, to vaccines and combination vaccines comprising such a virus, their use as a medicament, their use in the treatment of Bovine Viral...
US20140170164 Yersinia spp. Polypeptides and Methods of Use  
The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and...
US20150259746 BIOMARKER SIGNATURE METHOD, AND APPARATUS AND KITS THEREFOR  
The present invention discloses methods, kits, and apparatus as well as reagents and compositions associated therewith for deriving an indicator for use in diagnosing the presence, absence or...
US20140065195 UREAPLASMA VACCINE AND ANTIBODY FOR PREVENTION AND TREATMENT OF HUMAN, ANIMAL AND CELL CULTURE INFECTION  
The present invention encompasses methods and compositions for Ureaplasma infection prevention and/or treatment. In specific cases, the invention concerns vaccines for Ureaplasma, including DNA...
US20090169568 Antigenic Complex for the Diagnosis and Treatment of Porphyromonas Gingivalis Infection  
The present invention provides a purified multimeric complex form P. gingivalis. The complex comprises at least one domain from each of RgpA, Kgp and HagA, and has a molecular weight greater than...
US20150175707 DIMERIC PROTEIN WITH TRIPLE MUTATIONS  
The present invention relates to dimeric proteins comprising amino acids at three different positions which are different from those present in a human IgG1. Six of said dimeric proteins are...
US20140037649 DIAGNOSTIC AND/OR SCREENING AGENTS AND USES THEREFOR  
Disclosed are methods and apparatus for diagnosis, detection of host response, monitoring, treatment or management of sepsis, infection-negative systemic inflammatory response syndrome (SIRS) and...
US20110020216 SCAFFOLDS FOR CELL COLLECTION OR ELIMINATION  
A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated therein or thereon, or diffusing from the scaffold composition such that...
US20150030613 TREATMENT OF MUCOSITIS WITH IMMUNOGLOBULIN  
The invention relates to compositions comprising immunoglobulin for use in the treatment of mucositis by topical application. In particular, the invention relates to compositions comprising J...
US20150110806 CD147 AS RECEPTOR FOR PILUS-MEDIATED ADHESION OF MENINGOCOCCI TO VASCULAR ENDOTHELIA  
The present invention concerns the use of an inhibitor of an interaction between type IV pilus-associated protein and CD147 for preventing or treating meningoccal bacteraemia and/or infection. The...
US20150232517 MUTANT FRAGMENTS OF OspA AND METHODS AND USES RELATING THERETO  
The present invention relates to a polypeptide comprising a mutant fragment of an outer surface protein A (OspA), a nucleic acid coding the same, a pharmaceutical composition (particularly for use...
US20130045208 Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody  
The present invention relates to methods for the control of virulence of infectious bacteria by modulating the extra-cellular concentration of bacterial cell signalling molecules. Derivatives of...
US20100303831 Methods For The Treatment Of An Infectious Bacterial Disease With An Anti-Lactone Or Lactone Derived Signal Molecules Antibody  
The present invention relates to methods for the control of virulence of infectious bacteria by modulating the extra-cellular concentration of bacterial cell signalling molecules. Derivatives of...
US20130273074 Methods and Compositions Using Anti-LPS Ligands for the Treatment and Prevention of Inflammatory Disorders  
The present invention provides methods and compositions useful in the field of medicine, and particularly in the treatment of inflammatory disorders. More particularly, the invention relates to...
US20130189280 PROTEIN DOMAINS AND USES THEREFOR  
The present disclosure relates generally to a structure-modeling approach to identify therapeutic and diagnostic targets on proteins. Means are provided to generate agents which bind and...
US20110236306 COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS  
This invention provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an...
US20140271669 METHODS TO PRODUCE A HUMAN PLASMA-DERIVED IGG PREPARATION ENRICHED IN BRAIN DISEASE-RELATED NATURAL IGGS  
The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin G compositions highly enriched for anti-brain disease related protein antibodies...
US20150010579 Treatment and Prevention of Gardnerella Vaginalis Infections  
The present invention is drawn to the nucleic and amino acid sequences encoding vaginolysin (VLY) toxin from Gardnerella vaginalis, and biologically active fragments and variants thereof. The...
US20110020355 TREATMENT AND PREVENTION OF GARDNERELLA VAGINALIS INFECTIONS  
The present invention is drawn to the nucleic and amino acid sequences encoding vaginolysin (VLY) toxin from Gardnerella vaginalis, and biologically active fragments and variants thereof. The...
US20110054347 Devices for Selective Recruitment, Isolation, Activation, and/or Elimination of Various Cell Populations  
Implantable devices comprise at least one or more targeting molecules that form a primary coating layer for selectively recruiting, isolating, activating, and/or eliminating any cells of interest,...
US20140093518 Chemically Programmed Vaccination  
Provided herein is a method for chemically programmed vaccination. Methods include inducing a covalent-binding polyclonal antibody response in a subject and programming the polyclonal response...
US20100068214 Identification of Candidate Vaccine Antigens from Dichelobacter Nodosus  
This invention relates to a prophylactic and/or therapeutic treatment of footrot, and in particular to a vaccine effective in prophylactic and/or therapeutic treatment of footrot. Specific...
US20150050292 Detection, prevention, and treatment of Anthrax and other infectious diseases  
Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals...
US20140017258 Compositions against bacterial toxins  
Anti-toxin compositions are described that include avian antibodies against bacterial toxins. Administration of the anti-toxin compositions binds and neutralizes the bacterial toxin in the...
US20120189640 Methods and Compositions Related to Soluble Monoclonal Variable Lymphocyte Receptors of Defined Antigen Specificity  
Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal,...
US20060198849 Preparation method of igy for preventing and cure mouth disease and the toothpaste base on the igy  
The present invention relates to a preparation method of IgY for preventing and cure mouth disease, and a safe toothpaste containing the IgY.
US20110110857 MUTANT FORMS OF CHLAMYDIA HTRA  
An immunogenic Chlamydia HtrA protein, which has one or more mutations relative to wild-type Chlamydia HtrA that result in a reduced or eliminated protease activity relative to the protease...
US20110110954 Anthrax compositions and methods of use and production  
Compositions and methods effective for eliciting an immune response for preventing or reducing infection or improving clinical outcomes caused by Bacillus anthracis are provided. The compositions...
US20120164156 Recombinant F1-V Plague Vaccine  
Disclosed herein is a method of inducing an immunological response in a subject which comprises administering an immunogenic amount of a purified fusion protein comprising all or part of F1...
US20100291100 Compositions And Methods For Screening And Using Compounds Antagonizing Spore-Surface Interactions  
The present invention provides genes encoding novel microbial proteins (i.e., for example, exosporium genes and proteins) that mediate the attachment of microbial spores to surfaces. Specific...
US20110206692 CONFORMERS OF BACTERIAL ADHESINS  
The invention relates to isolated or purified bacterial adhesin conformers, preferably with improved stability and/or immunogenicity. In a preferred aspect, the invention comprises an isolated...
US20100150912 BLOCKING INTERACTION BETWEEN PATHOGEN FACTORS AND FACTOR H TO INHIBIT HEMORRHAGIC SYNDROMES  
If pathogen factors such as meningococcal NMB 1870 or flaviviral NS1 are able to sequester factor H in the blood then its inhibitory effect on complement may be disturbed, thereby permitting C3 to...
US20110206693 LYSINE RIBOSWITCH AND COMPOSITIONS AND USES THEREOF  
Embodiments herein provide for lysine riboswitches and analogs thereof, and methods for using the same. In certain embodiments, test compounds are identified that associate with lysine...
US20140271501 Methods and compositions for reducing microorganisms in the oropharynx, nasopharynx and oral cavities  
The present disclosure relates to methods and compositions administered to the lymphatic tissue of an animal to prevent or reduce the incidence of disease or disease symptoms caused by one or more...
US20060233781 Antimicrobial composition for local use on mucosal membranes and skin  
The invention relates to an antimicrobial composition for local use on mucosal membranes and skin. The antimicrobial composition comprises a system of lysozyme and glycosylated immunoglobulins....
US20120027771 AFFINITY PURIFIED HUMAN POLYCLONAL ANTIBODIES AGAINST VIRAL, BACTERIAL AND/OR FUNGAL INFECTIONS AND METHODS OF MAKING AND USING THE SAME  
The present invention discloses compositions and methods for treating, preventing and/or monitoring viral, bacterial, eukaryotic protist and/or fungal infections. In some embodiments, these...
US20050214279 Methods for stimulating human leukocytes to kill bacteria, yeast and fungi in biofilms that have formed in/on prosthetic devices, catheters, tissues and organs in vivo  
The present invention provides a method for stimulating human leukocytes to kill microorganisms in biofilms. The invention also provides a methods, compositions and kits for treating or preventing...
US20110236399 COMPOSITIONS AND METHODS FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF INFECTION  
This invention is directed to compositions and methods for treating (e.g., prophylactically and/or therapeutically) infection in a preterm infant. In particular, the invention provides...

Matches 1 - 50 out of 173 1 2 3 4 >