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US20110318265 Coupled identification and treatment of cancer  
Provided are methods to treat cancer in which a patient is identified as having gallium-avid cancer by use of a gallium scan or other means, and is then treated with a pharmaceutically acceptable...
US20140322203 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20140314778 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20120201857 Transdermal delivery system for therapeutics  
The present invention provides a method and product for transdermal delivery of therapeutics, including neurotoxins and methods for use thereof. The method and system comprises pharmaceutical...
US20120276109 TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS  
Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses...
US20150010509 CALCIUM FOLATE (CAFOLATE) AND THERAPEUTIC METHODS BASED THEREON  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection, tuberculosis and type 2 diabetes based upon the...
US20120251495 PTERIN BASED THERAPIES FOR INFLAMMATORY CONDITIONS  
Disclosed herein are methods for the treatment of cancer and inflammatory-based diseases and disorders, such as hepatitis B virus infection based upon the administration of calcium pterin. In one...
US20140308272 TREATMENT OF PRION PROTEIN RELATED DISEASES  
According to the present invention, treatment of prion protein related diseases, and in particular cancer tumours, is effected by providing to a subject in need thereof a therapeutically effective...
US20110044975 TREATMENT OF PRION PROTEIN RELATED DISEASES  
According to the present invention, treatment of prion protein related diseases, and in particular cancer tumours, is effected by providing to a subject in need thereof a therapeutically effective...
US20110097367 MONOLITHIC IN-SITU CROSS-LINKED ALGINATE IMPLANTS  
A method of making and using a monolithic alginate implant is described. The implant is formed by providing an uncrosslinked, highly pure and high molecular weight alginate solution and injecting...
US20150218649 BIOMARKER ASSOCIATED WITH RISK OF MELANOMA REOCCURRENCE  
The present invention provides a method of predicting the risk of reoccurrence of melanoma in a patient from whom melanoma tissue was previously removed which comprises the following: a. obtaining...
US20140314757 PHYTOCANNABINOIDS FOR USE IN THE TREATMENT OF BREAST CANCER  
The present invention relates to phytocannabinoids for use in the treatment of a breast cancer. In a first embodiment the invention relates to an oral presentation of tetrahydrocannabinol (THC)...
US20150139946 DETECTING MUTATIONS IN DISEASE OVER TIME  
Provided is a method for monitoring a gene mutation associated with a cancer in a patient over time. Also provided is a method of selecting and/or applying treatment or therapy for a subject.
US20150158940 USE OF ANTAGONISTS TARGETING METALLOTHIONEIN TO TREAT INTESTINAL INFLAMMATION  
Metallothioneins are stress inducible proteins with modulating functions during inflammation. Antagonizing metallothioneins during gut inflammation reduces markers of inflammations and enhances...
US20130224213 Compositions and Methods for Stabilizing Protein-Containing Formulations  
The present invention relates to use of certain alkylglycoside compositions for the prevention of aggregation and oxidation of antibodies and other proteins in therapeutically useful formulations...
US20150203919 METHODS FOR PREDICTING THE SURVIVAL TIME AND TREATMENT RESPONSIVENESS OF A PATIENT SUFFERING FROM A SOLID CANCER WITH A SIGNATURE OF AT LEAST 7 GENES  
The present invention relates to a method for predicting the survival time of a patient suffering from a solid cancer comprising i) determining in a tumor sample obtained from the patient the gene...
US20110189184 MODULATION OF NEURAL STEM CELLS AND NEURAL PROGENITOR CELLS  
The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes...
US20110212081 KRÜPPEL-LIKE FACTORS AND FAT REGULATION  
Disclosed herein are methods and cell lines used in fat regulation. The methods and cell lines incorporate Krüppel-like factors including, without limitation, klf-1 and klf-3.
US20100303723 DRUG DELIVERY SYSTEMS USING FC FRAGMENTS  
The present invention provides drug delivery systems comprising FcRn binding partners (e.g., FcRn binding partner, Fc fragment) associated with a particle or an agent to be delivered. Inventive...
US20140056848 Method for the Treatment of Multiple Sclerosis  
A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to...
US20130219534 Methods for the Treatment and Prevention of Metabolic Disorders  
Described herein are methods for detecting, characterizing, preventing, and treating metabolic diseases, including obesity and obesity-associated disorders such as diabetes.
US20150132363 SOLID DRESSING FOR TREATING WOUNDED TISSUE  
Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of fibrinogen and a fibrinogen activator,...
US20110280808 Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins  
The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and...
US20110256064 Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins  
The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and...
US20110223156 REVERSIBLE GEL PROTEIN FORMULATION  
Reversible gel protein formulations, including pharmaceutical formulations, that inhibit protein aggregate formation are described, along with containers, e.g., a vial, ampoule or bottle; or an...
US20120076779 STABILIZATION OF IMMUNOGLOBULINS AND OTHER PROTEINS THROUGH AQUEOUS FORMULATIONS WITH SODIUM CHLORIDE AT WEAK ACIDIC TO NEUTRAL ph  
The present invention provides, among other aspects, storage stabile aqueous formulations of labile proteins at a mildly acidic to neutral pH. The present invention also provides methods for...
US20150118230 Pharmaceutical Use of FAM19A5 Involved in Regulating Gliogenesis  
The present invention relates to the pharmaceutical use of FAM19A5 involved in regulating gliogenesis, and more specifically, to the use of FAM19A5 in the prevention, diagnosis, or treatment of...
US20130022609 METHOD OF TREATING ANDROGEN INDEPENDENT PROSTATE CANCER  
The present invention is directed to a method treating prostate cancer. The method comprises administering to a patient in need thereof at least one compound selected from...
US20120020979 METHODS FOR TREATING IgE-MEDIATED DISORDER  
This invention relates to methods of treating IgE mediated disorders such as allergy and asthma based on activating surface-bound IgD molecules on basophils. The invention also relates to methods...
US20140328922 LOCAL, CONCOMITANT ADMINISTRATION OF TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE TYPE I AND TYPE IV HYPERSENSITIVITY  
Disclosed are methods and related compositions for concomitantly, locally administering immunosuppressants and doses of therapeutic macromolecules for reducing Type I and Type IV hypersensitivity.
US20100297137 Hematopoietic Lineage Cell Specific Protein (HS1) as a Marker for Lymphoid Malignancy  
Use of a phosphorylated form of hematopoietic-lineage-cell-specific-protein-1 (HS1) as a prognostic or diagnostic marker for a Lymphoid Malignancy, a disease in which B cell receptor stimulation...
US20120177650 THERAPY FOR ENTERIC INFECTIONS  
A method and composition for treating enteric pathogen infections in animals suffering from such infections or displaying diseases or conditions consistent with such infections or for preventing...
US20120003296 NEW METHODS OF TREATING DRY EYE SYNDROME  
The invention relates to a method of insulin eye drops for treating dry eye syndrome due to any and all etiological factors (Keratoconjunctivitis sicca), including Sjogren's syndrome, Meibomian...
US20110016544 Methods and compositions for detecting and treating retinal diseases based on metargidin (ADAM-15)  
The invention discloses multiple genes related to age-related macular degeneration (AMD) and/or phagocytosis by RPE cells of the eye, and methods and compositions for detecting and treating AMD...
US20150132226 TREATMENT OF CANCER  
This invention relates to the field of molecular physiology. Specifically, this invention relates to the prevention and/or treatment of cancer. Leucine-rich alpha-2-glycoprotein (Lrg1) has been...
US20120114575 METHODS FOR INHIBITING CUTANEOUS INFLAMMATION AND HYPERPIGMENTATION  
This invention provides a method of preventing or treating in a subject contact dermatitis which comprises administering to the subject an amount of a compound capable of inhibiting the stem cell...
US20130209476 TREATMENT OF INFLAMMATORY DISORDERS  
A method is provided for treating certain inflammatory disorders by inhibiting cadherin-11 function using a cadherin-11 antagonist.
US20140199262 METHOD FOR MANUFACTURING PROTEIN DRUG  
The present invention provides a method for manufacturing a virus-free protein drug, comprising (a) a filtration step of filtering a virus-containing protein solution through a small-pore size...
US20140199232 Targeted Therapeutic Nanoparticles  
Disclosure of methods and compositions related to chemical conjugations to nanoparticles of polysaccharides cross-linked to poloxamers as well as nano-sized colloids comprised of polysaccharides...
US20100310570 MAPC TREATMENT OF BRAIN INJURIES AND DISEASES  
The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same...
US20130064825 METHODS OF TREATING OR PREVENTING CHOLESTEROL RELATED DISORDERS  
The present invention relates to methods of treating or preventing cholesterol related disorders, such as hypercholesterolemia, hyperlipidemia or dyslipidemia, using antibodies against proprotein...
US20110262386 METHODS OF TREATING INFLAMMATION  
Disclosed herein, in certain embodiments, is a method for treating an MIF-mediated disorder. In some embodiments, the method comprises administering an active agent that inhibits (i) MIF binding...
US20150044224 MATERIALS AND METHODS FOR DIFFERENTIAL TREATMENT OF CANCER  
The present invention concerns differential therapeutic treatment of cancer patients based on prognostic antigen/antibody profiles used for predicting (prognosticating) a clinical response...
US20110305753 Treatment of celiac disease with IgA  
A process is provided for inhibiting symptoms of food allergy or food intolerance in a subject that includes the oral adminstration to the subject suffering from food allergy or food intolerance...
US20120315303 METHODS AND INTRAVASCULAR TREATMENT DEVICES USING PACLITAXEL FOR TREATMENT OF ATHEROSCLEROSIS  
Methods and intravascular treatment devices for treating atherosclerosis are provided.
US20120070406 THERAPEUTIC PROTEIN COMPOSITIONS HAVING REDUCED IMMUNOGENICITY AND/OR IMPROVED EFFICACY  
The present invention provides methods for reducing and/or evaluating the immunogenic potential of a therapeutic protein preparation. The present invention further provides pharmaceutical...
US20120039896 METHOD FOR INHIBITING CELLULAR ACTIVATION BY INSULIN-LIKE GROWTH FACTOR-1  
A method of inhibiting cellular activation by Insulin-like Growth Factor-1 (IGF-1) in a subject in need thereof (e.g., a subject afflicted with cancer, atherosclerosis, diabetic retinopathy or...
US20100151009 FORMULATIONS FOR DELIVERING INSULIN  
Oral insulin formulations and processes for preparing oral insulin formulations are provided.
US20100316650 SOLUBLE MIC POLYPEPTIDES AS MARKERS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER AND AUTOIMMUNE DISEASES OR CONDITIONS  
The present invention provides prognostic and diagnostic methods for cancer, as well as methods for monitoring or staging cancer. Methods involve assaying for tumor-derived soluble MIC...
US20110274739 METHODS FOR GOVERNING TISSUE GROWTH  
Resorbable polymer barrier membranes and methods of their applications are disclosed. In a broad embodiment, methods of governing tissue growth, or preventing tissue growth into a certain spatial...