Match Document Document Title
US20140105886 ASSOCIATION OF BIOMARKERS WITH PATIENT OUTCOME  
Glioblastoma multiforme (GBM) is an aggressive form of brain cancer. Biomarkers for GBM that provide prognostic and predictive information are useful because they provide the physician valuable...
US20140099300 METHODS FOR PREDICTING AND IMPROVING THE SURVIVAL OF GASTRIC CANCER PATIENTS  
The present invention provides assays and methods for predicting the post-operative survival of a subject having an early stage gastric cancer after tumor surgery. The present invention also...
US20110212157 DERMAL DELIVERY  
The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis,...
US20140322203 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20130302320 Use of Semaphorin-4D Binding Molecules to Promote Neurogenesis Following Stroke  
Provided herein are methods for promoting neurogenesis in neural tissue of a patient exhibiting at least one symptom of a central nervous system disorder, the method comprising administering to a...
US20110014190 USE OF B LYMPHOCYTE STIMULATOR PROTEIN ANTAGONISTS TO PROMOTE TRANSPLANTATION TOLERANCE  
The invention relates to methods of preventing, treating, ameliorating and otherwise inhibiting organ or transplant rejection in a patient by administering B Lymphocyte Stimulator antagonists. In...
US20130039905 Diazoxide For Use In The Treatment Or Prevention Of A Central Nervous System (CNS) Autoimmune Demyelinating Disease  
The invention relates to the use of diazoxide or a pharmaceutically acceptable salt thereof at low doses to treat a CNS autoimmune demyelinating disease selected from selected from multiple...
US20150238553 TRIPTERYGIUM WILFORDII EXTRACTS TO OVERCOME CHEMOTHERAPY RESISTANCE  
The invention provides extracts and compositions derived from Tripterygium wilfordii for overcoming drug resist-ance in cancer therapy. This invention relates to organic solvent extracts of T....
US20110243933 Perifosine and Capecitabine as a Combined Treatment for Cancer  
Treatment regimens comprising co-treatment of cancer with perifosine and capecitabine are disclosed herein, as well as pharmaceutical compositions and unit dosage forms thereof formulated to be...
US20140308272 TREATMENT OF PRION PROTEIN RELATED DISEASES  
According to the present invention, treatment of prion protein related diseases, and in particular cancer tumours, is effected by providing to a subject in need thereof a therapeutically effective...
US20110044975 TREATMENT OF PRION PROTEIN RELATED DISEASES  
According to the present invention, treatment of prion protein related diseases, and in particular cancer tumours, is effected by providing to a subject in need thereof a therapeutically effective...
US20120003209 METHODS AND KITS USED IN IDENTIFYING GLIOBLASTOMA  
The invention encompasses methods and kits used in the identification of invasive glioblastoma based upon the expression of Akt1, Akt2, and Akt3. The methods and kits also allow prediction of...
US20140105850 TREATMENT OF MULTIPLE SCLEROSIS WITH LAQUINIMOD  
The subject invention provides for methods of reducing the relapse rate and/or reducing the accumulation of physical disability in a relapsing-remitting multiple sclerosis human patient, the...
US20130272996 TREATMENT OF MULTIPLE SCLEROSIS WITH LAQUINIMOD  
The subject invention provides for methods of reducing the relapse rate and/or reducing the accumulation of physical disability in a relapsing-remitting multiple sclerosis human patient, the...
US20100322900 Treatment of multiple sclerosis with laquinimod  
The subject invention provides for methods of reducing the relapse rate and/or reducing the accumulation of physical disability in a relapsing-remitting multiple sclerosis human patient, the...
US20140314745 METHODS TO CONTROL PROTEIN HETEROGENEITY  
The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins...
US20130156760 Protein Formulations and Methods of Making Same  
The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may...
US20140322164 METHOD OF ASSESSING RISK OF PML  
The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).
US20150064240 MUC1 Based Glycolipopeptide Vaccine with Adjuvant  
Provided herein are liposomal glycolipopeptidic vaccine formulations comprising an adjuvant and an immunogen for immunotherapy and/or treatment of cancer.
US20120219617 MUC1 Based Glycolipopeptide Vaccine with Adjuvant  
Provided herein are liposomal glycolipopeptidic vaccine formulations comprising an adjuvant and an immunogen for immunotherapy and/or treatment of cancer.
US20110212090 Combinatorial Analysis and Repair  
A method for the repair of a unit, by specific diagnosis of the undesired state, and its appropriate repair, using said specific diagnosis as a means to repair in an appropriate way said unit. The...
US20110076274 MATERIALS AND METHODS RELATING TO A G-PROTEIN COUPLED RECEPTOR  
The present inventors demonstrate that the G-protein coupled receptor 55 (GPR55) is highly expressed in human aggressive breast cancer cells, and that the expression level may be correlated with...
US20150185219 Biomarker SPAG5  
There has been a recent shift in cancer therapy from one size fits all to a personalized and tailored treatment for individual patients to increase efficiency and avoid unnecessary toxicity. This...
US20150174062 BIODEGRADABLE DRUG DELIVERY SYSTEM  
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
US20120263779 BIODEGRADABLE DRUG DELIVERY SYSTEM  
A drug delivery system (DDS) comprised of segmented biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The segmented...
US20110027267 Fusion Proteins of Mannose Binding Lectins for Treatment of Disease  
Fusion proteins having sequences that target specific moieties such as carbohydrates, lipids, and/or proteins that are associated with certain cell types and/or pathogens; and a sequence that...
US20120189619 METHODS FOR TREATING A SPINAL DISORDER OR OSTEOARTHRITIS USING DOMINANT NEGATIVE TISSUE NECROSIS FACTOR  
Effective methods of treating a spinal disorder or osteoarthritis associated with a proinflammatory agent in a patient in need of such treatment, the method comprising administering an effective...
US20130216524 Predictors for Cancer Treatment  
The present invention provides methods of predicting a response to a cancer treatment by determining CD68 level or PSMB1 (P11A) polymorphism in a biological sample and the presence or quantity of...
US20130115208 HETERODIMERIC PROTEINS AND METHODS FOR PRODUCING AND PURIFYING THEM  
The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins, such as bispecific antibodies and other...
US20110158993 Train-R: A Cysteine Rich Member of the TNF-Receptor Family  
Novel receptor in the TNF family: TRAIN-receptor.
US20140335082 COMBINATION THERAPY COMPRISING AN MMP-14 BINDING PROTEIN  
Proteins that bind to matrix metalloproteinase 14, combination therapies with such proteins and methods of using such proteins are described.
US20120201821 Treatment of Gastrointestinal Inflammation and Psoriasis and Asthma  
The present invention provides methods and means to reduce gastrointestinal inflammation. In particular, the invention provides methods and means to treat inflammatory bowel disease (IBD) and...
US20140356354 THERAPY FOR FILOVIRUS INFECTION  
The present invention addresses a need for improved treatments for filovirus infections.
US20150004154 REGIMEN FOR SUPPRESSING ORGAN REJECTION  
The present invention relates to a method of suppressing organ rejection in a patient receiving an organ transplant by initiating oral treatment with a once-daily extended release tacrolimus...
US20110268729 TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS BY NOGO-A-ANTAGONIST  
The invention relates to methods for the treatment or prophylaxis of amyotrophic lateral sclerosis, comprising administering to a patient in need thereof a therapeutically effective amount of a...
US20140140992 Sustained Release Formulations for Delivery of Proteins to the Eye and Methods of Preparing Same  
The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are...
US20120121589 MODIFIED EGFR ECTODOMAIN  
A protein that attenuates EGFR and/or EGFR family members comprises a modified EGFR ectodomain. The protein inhibits signaling via the EGFR and/or EGFR family members. The protein includes a...
US20140328832 METHODS FOR TREATING CANCER USING COMBINATION THERAPY  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a substituted quinazolinone compound and an effective amount of...
US20150037251 MAMMALIAN HOMOLOGUES OF FLOWER, THEIR USE IN CANCER DIAGNOSTICS, PREVENTION AND TREATMENT  
The invention relates inhibiting nucleic acids directed at mammalian homologues of the Drosophila fwe gene (Flower) and to antibodies against the respective proteins, and their use in diagnosing,...
US20110014191 BREAST CANCER EXPRESSION PROFILING  
The present invention relates to a method for analyzing cancer. e.g., breast cancer including detection of differential expression of at least one of the 16 genes encoding serine/threonine kinases...
US20140363425 SYSTEMS AND METHODS FOR IDENTIFYING CANCERS HAVING ACTIVATED PROGESTERONE RECEPTORS  
Systems and methods for identifying tumors having activated progesterone receptors are provided. Patients suspected of having a tumor susceptible to growth inhibition by anti-progestins can be...
US20110052581 USE OF PICOPLATIN AND CETUXIMAB TO TREAT COLORECTAL CANCER  
The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with cetuximab, 5-FU, and leucovorin in a...
US20150152503 MICRORNAS FOR PREDICTION OF TREATMENT EFFICACY AND PROGNOSIS OF CANCER PATIENTS  
The present invention lies within the field of personalised medicine. More particular the invention relates to biomarkers useful for predicting treatment efficacy and prognosis in cancer patients....
US20150044217 METHODS FOR THE TREATMENT OF HER2 AMPLIFIED CANCER  
Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
US20110177066 PREVENTION AND TREATMENT OF AMYLOIDOGENIC DISEASES  
Passive immunotherapy methods for treating a patient having AL amyloidosis characterized by the presence of amyloid light chain-type protein fibrils.
US20150218649 BIOMARKER ASSOCIATED WITH RISK OF MELANOMA REOCCURRENCE  
The present invention provides a method of predicting the risk of reoccurrence of melanoma in a patient from whom melanoma tissue was previously removed which comprises the following: a. obtaining...
US20140314757 PHYTOCANNABINOIDS FOR USE IN THE TREATMENT OF BREAST CANCER  
The present invention relates to phytocannabinoids for use in the treatment of a breast cancer. In a first embodiment the invention relates to an oral presentation of tetrahydrocannabinol (THC)...
US20110217303 ANTAGONISTS OF IL-6 TO PREVENT OR TREAT CACHEXIA, WEAKNESS, FATIGUE, AND/OR FEVER  
The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in...
US20130164279 Micro RNA-148A as a Biomarker for Advanced Colorectal Cancer  
The present invention includes methods of detection, diagnosis, prognosis, and treatment of a patient suspected of having a colorectal cancer comprising obtaining one or more samples of the...
US20100330086 CATIONIC STEROID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE  
The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a...