Matches 51 - 100 out of 248 < 1 2 3 4 5 >


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US20110268725 Anti-NGF antibodies for the treatment of various disorders  
The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including asthma, arthritis and psoriasis. The methods are...
US20130129714 PREVENTION AND TREATMENT OF CAST NEPHROPATHY  
Provided herein are polypeptides comprising or consisting essentially of a QSYDNTLSGSYVF (SEQ ID NO:1) or LSADSSGSYLYVF (SEQ ID NO:2) amino acid sequence. Also provided herein are methods of...
US20090053294 Anti Mineralocorticoid Therapy of Infection  
Antimineralocorticoid compounds are disclosed for use in the prophylaxis and therapy of viral infections, especially the retroviral infection by HIV. These compounds can be administered alone or...
US20150239989 METHODS FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE  
The present invention provides methods of treating a mammal having chronic obstructive pulmonary disease (COPD), independent of both smoking status and asthma status, with a therapeutically...
US20080193440 Method For Multiple Sclerosis Treatment and Prophylaxis By Treatment of Leptospira Infection  
The present invention provides novel therapies and novel prophylactic methods for multiple sclerosis. Also provided are novel diagnostic methods. The invention resides in the finding that multiple...
US20060286090 Mediators of epithelial adhesion and their role in cancer and skin disorders  
Perp is shown to mediate stratified epithelial development in vivo. Perp localizes specifically to desmosomes, adhesion junctions important for tissue integrity. In some embodiments of the...
US20060165676 Identification of tsh receptor autoantibodies using affinity-purified antibodies  
The present invention relates to the use of affinity-purified polyclonal human autoantibodies against the TSH receptor (TSHR-Auto-Ab), obtained from the serum of Graves' disease patients and which...
US20050019321 Method of obtaining protection against bystander allergen  
The present invention relates to a method of obtaining protection against, simultaneously, a specific allergen and a by-stander allergen. The method comprises the administration of a compound...
US20070292417 Chimeric allgraft tolerance induction, monitoring and maintenance  
A method is provided for inducing donor-specific tolerance and/or mixed donor-recipient chimerism in an allograft transplant recipient, by administering to a recipient of an allograft a...
US20090208486 Pharmaceutical composition comprising cxcr3 inhibitor  
A pharmaceutical composition for the treatment of cancer of which survival and/or metastasis is under the influence of signal transduction mediated by a chemokine receptor CXCR3, which comprises...
US20110129456 Sequential Administration of Chemotherapeutic Agents for Treatment of Cancer  
The present invention relates to the sequential administration of a cytotoxic agent followed by an IGF1R antagonist (e.g., an antibody) for the treatment of hyperproliferative disorders including...
US20110059068 POLYPEPTIDES INVOLVED IN IMMUNE RESPONSE  
Polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding the polypeptides, and vectors and host cells for expressing the...
US20090017016 Treatment and prevention of hypersensitivity and/or anaphylaxis with anti-ige antibodies in patients receiving replacement therapy  
The present invention relates generally to a method of treatment and/or prevention of hypersensitivity including anaphylaxis in patients receiving replacement therapy molecules that elicit an...
US20110086023 COMBINATION ANTIHISTAMINE MEDICATION  
The invention provides a topical pharmaceutical composition for application to the nasal or ocular mucosa which comprises (1) a pharmaceutical excipient suitable for topical administration, (2) a...
US20120328615 ANTI-KIR ANTIBODIES FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISORDERS  
This invention relates to compounds that inhibit KIR2DL1, 2 and/or 3 polypeptide comprising compounds (e.g., anti-KIR2DL1, 2, and/or 3 antibodies) that neutralize NK cell inhibitory receptors and...
US20090317381 CLEARANCE OF ABNORMAL IGA1 IN IGA1 DEPOSITION DISEASES  
The present invention relates to proteins which specifically bind to IgA1 and which have been modified to comprise either O- or N-linked glycans. The invention encompasses methods for decreasing...
US20100233118 USE OF WF10 FOR TREATING ALLERGIC ASTHMA, ALLERGIC RHINITIS AND ATOPIC DERMATITIS  
The present invention provides a method of inhibiting at least one of allergic asthma, allergic rhinitis and atopic. The present invention further provides a method for the reduction, prevention...
US20120177635 METHODS OF USING APOPTOTIC ANTI-IGE ANTIBODIES  
The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
US20130121992 MOLECULES AND METHODS FOR TREATMENT OF DIABETES  
Described are antibodies that specifically recognize and bind the epitope of glutamate decarboxylase (GAD65) that is bound by antibody b96.11, and anti-idiotypic antibodies that are capable of...
US20110052569 MOLECULES AND METHODS FOR TREATMENT OF DIABETES  
Described are antibodies that specifically recognize and bind the epitope of glutamate decarboxylase (GAD65) that is bound by antibody b96 11, and anti-idiotypic antibodies that are capable of...
US20110135633 CHRONIC LYMPHOCYTIC LEUKEMIA CELL LINE  
The preparation and characterization of antibodies that bind to antigens on CLL or other cancer cells, especially to antigens upregulated in the cancer cells, and the identification and...
US20150225485 HIGH CONCENTRATION ANTIBODY AND PROTEIN FORMULATIONS  
The present application relates to highly concentrated antibody and protein formulations with reduced viscosity that are stable, relatively isotonic and are of low turbidity. The formulations are...
US20120230979 NOGO Receptor Binding Protein  
The invention provides Sp35 polypeptides and fusion proteins thereof, Sp35 antibodies and antigen-binding fragments thereof and nucleic acids encoding the same. The invention also provides...
US20100143340 METHODS AND COMPOSITIONS FOR TREATING CANCER  
The present invention provides methods for preventing or treating a medical disorder in a subject comprising administering to the subject an effective amount of a stable pharmaceutical formulation...
US20110212085 LUNG CANCER DISEASE TARGETS AND USES THEREOF  
The present invention provides a method for diagnosing and detecting diseases associated with lung. The present invention provides one or more proteins or fragments thereof, peptides or nucleic...
US20050169914 Novel functions for decay accelerating factor (DAF) in inflammation  
The invention involves methods and products for interfering with neutrophil transmigration and treating inflammatory conditions. Agents that bind decay accelerating factor (DAF) and agents that...
US20100150904 BINDING MEMBERS FOR IGE MOLECULES  
This invention relates to binding members, especially antibody molecules, for IgE. The binding members are useful for, inter alia, treatment of disorders mediated by IgE including allergies and...
US20050249722 Monoclonal antibodies with enhanced ADCC function  
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan...
US20110123447 METHOD OF PROVIDING HUMAN TUMOR-SPECIFIC ANTIBODIES  
Provided are novel tumor-specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize tumor-associated antigens and that are...
US20050112062 Anti-idiotypic vascular endothelial growth factor antibodies and their use as medicaments  
An anti-idiotypic vascular endothelial growth factor antibody, an Fab fragment, and pharmaceutical compositions thereof, being ligands of the human KDR receptor or of the murine flk-1 receptor and...
US20120141463 Method Of Identifying Membrane Ig Specific Antibodies And Use Thereof For Targeting Immunoglobulin-Producing Precursor Cells  
The present invention relates to the discovery of antibodies that bind to novel epitopes present on membrane-anchored immunoglobulins and which bind to these novel epitopes on the surface of B...
US20050271651 Inhibition of bright function as a treatment for excessive immunoglobulin production  
The present invention involves the identification of Bright as involved in immunoglobulin production, and the targeting of that function for the treatment of disease states associated with...
US20100266531 IL-17 BINDING PROTEINS  
Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in...
US20090010924 Apoptotic Anti-IgE Antibodies  
The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
US20120282223 Amorphous (5-Fluoro-2-methyl-3-quinolin-2-ylmethyl-indol-1-yl)-Acetic Acid  
The invention relates to a stable amorphous form of (5-Fluoro-2-methyl-3-quinolin-2-ylmethyl-indol-1-yl)-acetic acid and its use in the treatment of conditions mediated by the action of PGD2 at...
US20140363422 METHOD OF PROVIDING MONOCLONAL AUTO-ANTIBODIES WITH DESIRED SPECIFICITY  
Provided are novel binding molecules of human origin, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize antigens such as native endogenous...
US20150132286 PANCREATIC CANCER TARGETS AND USES THEREOF  
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or...
US20060099201 Treating a mammal with a formulation comprising an antibody which binds IgE  
A method of treating a mammal with a formulation comprising an antibody which binds IgE as described.
US20070190045 Anti-CD3 and antigen-specific immunotherapy to treat autoimmunity  
The invention provides methods for treating autoimmunity and for reestablishing tolerance. The methods involve the coadministration of anti-CD3 antibodies and self-antigens. The coadministration...
US20070286855 IMPROVING TREATMENTS  
Methods and materials for reducing a mammal's ability to produce antibodies against an antigen (e.g., a therapeutic polypeptide) to be administered to the mammal are provided herein.
US20140134154 Immunological Compositions as Cancer Biomarkers and/or Therapeutics  
The present invention concerns antibodies that react immunologically with anti-tumor antigen antibodies and compositions and methods related thereto. In particular, the antibodies that react...
US20110064726 ANTI IgE ANTIBODIES  
The present invention relates to novel human antibodies specifically directed against human immunoglobulin E (anti-IgE). The present invention also relates to pharmaceutical compositions and...
US20100291023 METHOD FOR EXTENDING THE HALF-LIFE OF EXOGENOUS OR ENDOGENOUS SOLUBLE MOLECULES  
The present invention relates to methods for extending the in vivo half-life of an exogenous soluble therapeutic molecule administered to a subject, by administering to said subject the exogenous...
US20120114745 METHOD FOR TREATING OR AMELIORATING MUCOCUTANEOUS OR OCULAR TOXICITIES  
A method for treating or ameliorating mucocutaneous, ocular toxicities, or side effects induced by blocking cellular growth and survival signal transduction pathways. The method comprises...
US20110274651 Noscapine and Noscapine Analogs and Their Use in treating Infectious Diseases by Tubulin Binding Inhibition  
Compositions and methods for treating or preventing infectious diseases, and inhibiting the ability of microbes to travel within mammalian cells, and inhibiting microbial replication, are...
US20130243750 ANTI-IGE ANTIBODIES AND METHODS USING SAME  
This invention provides anti-IgE antibodies that bind to the M1′ segment of a human IgE and their use in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE...
US20110091449 Isolation of Anti-Desmoglein 1 Antibodies by Phage Display of Pemphigus Foliaceus Autoantibodies  
This invention relates to compositions and methods for the use of anti-autoimmune reagents that specifically bind to anti-desmoglein antibodies, which are responsible for pemphigus foliaceus. In...
US20090317382 USE OF EFFECTOR-FUNCTION-DEFICIENT ANTIBODIES FOR TREATMENT OF AUTO-IMMUNE DISEASES  
The invention relates to the treatment of autoimmune diseases and disorders, in particular myasthenia gravis, by administration of effector-function-deficient antibodies, wherein said...
US20100104562 Enhancing Efficacy of Vaccines Administered Via the Respiratory Tract  
Disclosed herein are vaccine compositions comprising live attenuated virus with anti-antibody to improve efficacy. Specifically exemplified herein is a composition comprising live attenuated cold...
US20070298033 Human Anti-Idiotypic Antibody Fragments that Mimic Her-2/Neu  
This invention relates to human anti-idiotypic antibody fragments, especially scFv, characterized by the ability to mimic Her-2/neu tumor associated antigen. These antibody fragments are promising...

Matches 51 - 100 out of 248 < 1 2 3 4 5 >