Matches 1 - 50 out of 369 1 2 3 4 5 6 7 8 >


Match Document Document Title
US20120052010 IMAGING TUMOR PERFUSION, OXIDATIVE METABOLISM USING DYNAMIC ACE PET IN PATIENTS WITH HEAD AND NECK CANCER DURING RADIOTHERAPY  
The present invention provides methods of using optimal PET tracers for diagnosing head and neck cancer. Non-invasive methods for assessing tumor perfusion and oxidative metabolism for in vivo...
US20120207678 Labeled Adenosine for Use in Positron Emission Tomography  
Radiolabeled adenosine or radiolabeled adenosine containing molecules for use in positron emission tomography for assessing alterations in adenylate metabolism in a patient are provided.
US20130224114 Translocator Protein Ligands  
The present invention relates to compounds and methods for imaging translocator protein (18 kDa) (TSPO) expression in a subject. This invention also relates to compounds and methods for the...
US20110044898 TRANSLOCATOR PROTEIN LIGANDS  
The present invention relates to compounds and methods for imaging translocator protein (18 kDa) (TSPO) expression in a subject. This invention also relates to compounds and methods for the...
US20130183240 IN VIVO IMAGING METHOD FOR CANCER  
The present invention provides a method useful in the diagnosis and monitoring of cancer wherein there is an abnormal expression of PBR. The method of the invention is particularly useful in...
US20120107240 Probes and methods of melanoma imaging  
Embodiments of the present disclosure provide for labeled probes such as a 3-18F-fluoropicolinamide probe, methods of making labeled probes, pharmaceutical compositions including labeled probes,...
US20130183238 Formulation, Apparatus and Method for Stabilizing Radiopharmaceuticals  
A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a...
US20120020881 Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes  
This invention relates to novel compounds suitable for labeling by positron emitting isotopes, such as 18F, 11C, 13N and 15O, through appropriate labeling reagents, such as 18F reagents and...
US20110293520 NEW DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES  
The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of...
US20130084245 PET MONITORING OF A-BETA-DIRECTED IMMUNOTHERAPY  
The present invention provides methods of monitoring Aβ-directed immunotherapy. The methods involve administering a PET ligand that binds to amyloid deposits and detecting the PET ligand in the...
US20140079635 MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION  
A method of detecting myelin in a subject includes administering to the subject a molecular probe that includes a fluorescent trans stilbene derivative and detecting the amount or distribution of...
US20130164217 METHOD OF DIAGNOSING, PREVENTING AND/OR TREATING DEMENTIA & RELATED DISORDERS  
Described are assay methods, modules and kits useful in the detection, treatment and/or prevention of dementia and related conditions, including but not limited to Alzheimer's disease and mild...
US20150023877 METHODS OF PARKINSONS DISEASE DIAGNOSIS AND MONITORING TREATMENT  
Embodiments of the present disclosure provide for methods of using labeled probes, methods of diagnosing Parkinson's disease and related biological events, methods of using labeled probes for...
US20140170067 NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES  
The present invention relates to novel compounds of formulae (I) and (II) which are useful in the prevention, treatment and diagnosis, in vivo diagnosis of diseases or disorders related to S1P...
US20110070160 Dose Synthesis Mosule for Biomaker Generator System  
A microfluidic radiopharmaceutical production system and process for synthesizing per run approximately, but not less than, one (1) unit dose of a radiopharmaceutical biomarker for use in positron...
US20150231279 METHODS AND COMPOSITIONS FOR DETECTING DRUSEN AND PREDICTING AGE-RELATED MACULAR DEGENERATION  
Labels and methods are provided for detecting deposits, including drusen, sub-retinal deposits, basal laminar and linear deposits, and the like. The labels can detect the presence, progression, or...
US20130336890 COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM  
This invention relates to novel compounds suitable as precursors for the preparation of certain 18F labelled positron emission tomography (PET) tracers. Furthermore the invention relates to the...
US20150157743 Dose Synthesis Card for Use with Automated Biomarker Production System  
Microfluidic radiopharmaceutical production system and process for synthesizing per run approximately, but not less than, ten (10) unit doses of radiopharmaceutical biomarker for use in positron...
US20110189089 RADIOFLUORINATION  
The present invention relates to 18F radio-chemistry and in particular to a method for synthesising radiofluorinated amides and amines. The method of the invention has particular application in...
US20130101509 IMAGING AND RADIOTHERAPY METHODS  
The present invention relates to in vivo imaging and radiotherapeutic methods and agents which target the enzyme aldehyde dehydrogenase (ALDH) and that are suitable for the in vivo imaging of...
US20110286922 IMAGING AND RADIOTHERAPY METHODS  
The present invention relates to in vivo imaging and radiotherapeutic methods and agents which target the enzyme aldehyde dehydrogenase (ALDH) and that are suitable for the in vivo imaging of...
US20150133777 POSITRON EMISSION TOMOGRAPHY PROBE TO MONITOR SELECTED SUGAR METABOLISM IN VIVO  
The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods...
US20130028837 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING  
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
US20120276006 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING  
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
US20150079001 IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA  
The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of...
US20120276007 IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA  
The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of...
US20100310457 IMAGING OF MYELIN BASIC PROTEIN  
The present invention relates to methods for myelin basic protein detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering...
US20130101510 METHODS OF TREATING PARKINSON'S DISEASE USING VIRAL VECTORS  
Methods of delivering viral vectors, particularly recombinant AAV virions, to the CNS are provided. Also provided are methods of treating Parkinson's Disease.
US20120039803 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN  
Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal...
US20130177501 IN VIVO IMAGING METHOD OF MOOD DISORDERS  
The present invention provides a method useful in the diagnosis and/or monitoring of mood disorders wherein there is an abnormal expression of PBR. The method of the invention is useful in the...
US20110142759 AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN  
The present invention relates to agents capable of binding to myelin basic protein in a subject. Also provided are methods for the detection of myelin-associated neuropathy comprising identifying...
US20120121509 VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE  
The present invention provides compositions and methods based on vital fluorochrome conjugates that are useful for imaging dying and dead cells.
US20130266512 Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes  
A Diels-Alder adduct of a trans-cyclooctene with a tetrazine is provided, wherein the adduct bears a substituent labeled with a radionuclide. A method of producing a PET or other image of an organ...
US20130302248 Imaging Agents for Detecting Neurological Disorders  
Imaging agents of formula (I) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formula (I) capable of binding to tau proteins and...
US20110182812 Imaging Agents for Detecting Neurological Disorders  
Imaging agents of formulas (I)-(V) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formulas (I)-(V) capable of binding to tau proteins...
US20150010474 Compounds And Methods For Selective Imaging And/Or Ablation  
The invention relates generally to compounds and methods for imaging and/or selective ablation of nitroreductase-expressing cells and/or biological agents. More particularly, although not...
US20140134107 COMPOUNDS, PROBES, AND METHODS OF SYNTHESIS AND METHODS OF IMAGING COX-2-ASSOCIATED DISEASES  
Embodiments of the present disclosure provide for a compound, methods of making a compound, a probe, methods of making a probe, pharmaceutical compositions including a probe or a compound, methods...
US20140341808 CONTRAST AGENT FOR IMAGINING MYOCARDIAL PERFUSION  
Compounds and a method for imaging myocardial perfusion, including administering to a patient a compound linked to an imaging moiety, wherein the compound binds MC-1, and scanning the patient...
US20120294803 CXCR4 ANTAGONISTS FOR IMAGING OF CANCER AND INFLAMMATORY DISORDERS  
The invention provides radiolabeled CXCR4 antagonists, compositions and methods of use for imaging of chemokine CXCR4 receptors and biological conditions associated with the expression of CXCR4...
US20140335019 COMPOSITIONS AND METHODS FOR THE TREATMENT AND ANALYSIS OF NEUROLOGICAL DISORDERS  
Provided herein are compositions and methods for the treatment and analysis of neurological disorders. In particular, provided herein are small molecules targeted to amyloid-β (Aβ) or metal-Aβ...
US20130209363 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS  
This invention relates to methods, which provide access to [F-18]fluoropegylated (aryl/heteroaryl vinyl)-phenyl methyl amine derivatives.
US20120213703 RADIOLABELLED PDE10 LIGANDS  
The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET)....
US20110305637 RADIOLABELLED PDE10 LIGANDS  
The present invention relates to novel, selective, radiolabeled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues using positron-emission tomography (PET)....
US20150023873 EVALUATION OF PRESENCE OF AND VULNERABILITY TO ATRIAL FIBRILLATION AND OTHER INDICATIONS USING MATRIX METALLOPROTEINASE-BASED IMAGING  
The invention provides, in some embodiments, methods relating to assessing increased risk of developing atrial fibrillation (AF), and/or the likelihood of responding to particular AF therapies...
US20140004044 USE OF FLUORINATED DERIVATIVES OF 4-AMINOPYRIDINE IN THERAPEUTICS AND MEDICAL IMAGING  
The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including for the treatment of...
US20110008254 RADIOPHARMACEUTICAL COMPOSITION  
The present invention relates to radiopharmaceuticals and in particular to a radiopharmaceutical composition comprising a compound of Formula (I): and polysorbate as an excipient. The...
US20130259805 DEVELOPMENT AND SCREENING OF CONTRAST AGENTS FOR IN VIVO IMAGING OF PARKINSON'S DISEASE  
The invention provides compounds and a method for imaging aggregated α-synuclein, e.g., Lewy bodies or Lewy neurites, in a tissue or organ.
US20090257949 Radiopharmaceutical Imaging of Neurodegenerative Diseases  
Methods for simultaneously detecting dementia or cognitive impairment, such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Lewy Body Dementia (LBD) and Vascular Dementia (VaD) in a patient...
US20130343994 Cholinesterase Inhibitors  
The invention provides compounds that inhibit cholinesterases, such as acetylcholinesterase and butyrylcholinesterase. Such compounds are useful to prevent or treat exposure of a patient (e.g., a...
US20120321561 CANCER DIAGNOSIS AND IMAGING  
The present invention provides a method for imaging a disease or condition in a mammal which includes the steps of; administering a therapeutically effective amount of a cell cycle inhibitor to...

Matches 1 - 50 out of 369 1 2 3 4 5 6 7 8 >