Matches 1 - 50 out of 371 1 2 3 4 5 6 7 8 >


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US20140363374 COUPLED IDENTIFICATION AND TREATMENT OF CANCER  
Provided are methods to treat cancer, in which (1) a patient is first identified as having a cancer that is likely to be susceptible to gallium therapy, by the use of a gallium scan or other...
US20140093451 Coupled identification and treatment of cancer  
Provided are methods to treat cancer, in which (1) a patient is first identified as having a cancer that is likely to be susceptible to gallium therapy, by the use of a gallium scan or other...
US20140341806 NON-INVASIVE DIAGNOSTIC AGENTS OF CANCER AND METHODS OF DIAGNOSING CANCER, ESPECIALLY LEUKEMIA AND LYMPHOMA  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
US20130216478 Non-Invasive Diagnostic Agents of Cancer and Methods of Diagnosing Cancer, Especially Leukemia and Lymphoma  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
US20120070372 NON-INVASIVE DIAGNOSTIC AGENTS OF CANCER AND METHODS OF DIAGNOSING CANCER, ESPECIALLY LEUKEMIA AND LYMPHOMA  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
US20140356283 Probes, Methods of Making Probes, and Methods of Use  
Embodiments of the present disclosure provide for water soluble polyethylene glycol (PEG)-polymeric melanin (PEG-melanin) nanoparticles, methods of using the PEG-melanin nanoparticle, methods of...
US20150157712 CANCER TREATMENT  
A carborane-comprising porphyrin of Formula (1) is provided for use in cancer therapy that extends the period of time between the doses required while the patient is undergoing radiation therapy....
US20120189543 Compositions and Methods for Detecting and Treating Implant Loosening and Osteolysis  
Methods and compositions for detecting, diagnosing, and treating osteolysis and implant loosening are disclosed.
US20150010472 METHOD OF USING ADENOSINE AND DIPYRIDAMOLE FOR PHARMACOLOGIC STRESS TESTING, WITH SPECIFIC COMPOSITIONS, UNIT DOSAGE FORMS AND KITS  
Methods for detecting the presence and/or assessing the severity of myocardial ischemia during pharmacologic stress tests by administration of a pharmaceutical composition comprising adenosine and...
US20110142756 Method And Composition For The Treatment Of Cancer By The Enzymatic Conversion Of Soluble Radioactive Toxic Precipitates In The Cancer  
The invention features compositions and methods for treating or alleviating a symptom of cancer. The compositions and methods of the invention direct supra-lethal doses of radiation, called...
US20110236310 LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD  
The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as...
US20120128585 Method of Diagnosing the presence of a tumor in a mammal by assessing CDO expression level  
The present invention provides for a method of using BOC/CDO hedgehog antagonists to inhibit hedgehog signaling, as well as treating and diagnosing disorders relating to hedgehog signaling or...
US20120269724 COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS  
The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another...
US20110236307 IN VIVO IMAGING METHOD  
The present invention provides an in vivo imaging method that facilitates the diagnosis of Parkinson's disease (PD) at an early stage. Early diagnosis is particularly advantageous as...
US20150231279 METHODS AND COMPOSITIONS FOR DETECTING DRUSEN AND PREDICTING AGE-RELATED MACULAR DEGENERATION  
Labels and methods are provided for detecting deposits, including drusen, sub-retinal deposits, basal laminar and linear deposits, and the like. The labels can detect the presence, progression, or...
US20120095324 METHOD FOR A NUCLEAR MEDICINE EXAMINATION  
A method for a nuclear medicine examination of a patient is disclosed. In at least one embodiment of the method, a magnetic resonance recording of an examination region of the patient is created...
US20140037541 RADIOIMAGING METHODS USING TEBOROXIME AND THALLIUM  
A method for imaging is providing, including administering a teboroxime species to an adult human subject, administering T1-201-thallous chloride to the subject performing a teboroxime species...
US20150017097 Sincalide Formulations  
The invention features sincalide formulations that include an effective amount of sincalide, a bulking agent/tonicity adjuster, a stabilizer, a surfactant, a chelator, and a buffer. The invention...
US20150157743 Dose Synthesis Card for Use with Automated Biomarker Production System  
Microfluidic radiopharmaceutical production system and process for synthesizing per run approximately, but not less than, ten (10) unit doses of radiopharmaceutical biomarker for use in positron...
US20140271466 HSPC-Sparing Treatments for RB-Positive Abnormal Cellular Proliferation  
This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the...
US20140377175 CHEMICALLY-LINKED NANOPARTICLES  
Provided herein are compositions and methods of preparing nanoparticle aggregates.
US20120128586 METHOD FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA  
The present invention provides a method for treating a subject having chronic lymphocytic leukemia (CLL) comprising administering to the subject one or more agents that target cell surface...
US20120276006 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING  
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds...
US20120039803 PRETARGETING KIT, METHOD AND AGENTS USED THEREIN  
Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal...
US20110038795 TARGETED RADIOTHERAPY  
The present invention concerns a therapeutically labeled napthodianthrone or phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound, which comprises a chemical element or an isotope that has an...
US20140079631 ANTI-INFLAMMATORY PARTICLES  
Described herein are compositions and methods relating to particles comprising at least one component of a cellular-derived microparticle. Aspects of technology described herein relate to...
US20120121509 VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE  
The present invention provides compositions and methods based on vital fluorochrome conjugates that are useful for imaging dying and dead cells.
US20130336887 COMPOUNDS AND METHODS FOR ENZYME-MEDIATED TUMOR IMAGING AND THERAPY  
The invention provides methods and compositions, e.g., for tumor imaging and therapy.
US20120045390 Composition and Methods for the Diagnosis and Treatment of Tumor  
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
US20110182810 CENTRAL NERVOUS SYSTEM LABELLING COMPOSITION FOR INTRANASAL ADMINISTRATION AND LABELLING METHOD AND SCREENING METHOD USING CENTRAL NERVOUS SYSTEM LABELLING COMPOSITION FOR INTRANASAL ADMINISTRATION  
There is provided a central nervous system labelling composition for intranasal administration for the purpose of labelling the central nervous system from the olfactory epithelium by way of the...
US20120225015 Method for predicting autism spectrum disorders by cannabinoid and cannabinoid receptor expression  
The inventive method relates to a method for the determination of susceptibility or diagnosis of autism or autism spectrum disorders. Diagnosis or determination of susceptibility determinations...
US20140154180 Pharmacophores for Amyloid Fibers Involved in Alzheimer's Disease  
This invention relates, e.g., to a method for designing or selecting on a computer a candidate small molecule amyloid binder or inhibitor, comprising: a) docking test compounds to the binding site...
US20140193336 IMAGING PROTOCOLS  
Protocols for radioimaging an event or disorder are provided. An exemplary protocol comprises a method of radioimaging a myocardial perfusion, the method comprising in sequence: (a) administering...
US20110189086 Diagnostic Method for Atherosclerosis  
The invention relates to a method of identifying/monitoring active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible...
US20100322854 POSITRON EMISSION TOMOGRAPHY IMAGING METHOD  
Described herein are compositions and methods for diagnosing and/or monitoring pathogenic disease states using positron emission tomography, wherein the pathogenic cells uniquely express,...
US20100284913 Methods and compositions for studying, imaging, and treating pain  
Saxitoxin analogue compounds, compositions, pharmaceutical compositions, methods of synthesis of saxitoxin analogues, methods of imaging, methods of treatment, including methods of treating pain,...
US20150023873 EVALUATION OF PRESENCE OF AND VULNERABILITY TO ATRIAL FIBRILLATION AND OTHER INDICATIONS USING MATRIX METALLOPROTEINASE-BASED IMAGING  
The invention provides, in some embodiments, methods relating to assessing increased risk of developing atrial fibrillation (AF), and/or the likelihood of responding to particular AF therapies...
US20150110716 METHODS OF USING SPECT/CT ANALYSIS FOR STAGING CANCER  
A method of evaluating a subject suspected of harboring a prostrate tumor includes administering to the subject an effective amount of a gamma-emitting transition metal complex conjugated to a...
US20120207674 CANCER-IMAGING AGENT AND METHOD OF RADIOIMAGING USING THE SAME  
The cancer-imaging agent and method of radioimaging relates to the use of a radioimaging agent for the imaging increased choline uptake to detect cancerous tissue. The radioimaging agent includes...
US20120003151 METHOD FOR EARLY IMAGING OF ATHEROSCLEROSIS  
The invention relates to methods of detecting active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible binding sites...
US20110104056 NOVEL MOLECULAR ASSEMBLY, MOLECULAR PROBE FOR MOLECULAR IMAGING AND MOLECULAR PROBE FOR DRUG DELIVERY SYSTEM USING THE SAME, AND MOLECULAR IMAGING SYSTEM AND DRUG DELIVERY SYSTEM  
The present invention provides a molecular assembly which is less likely to accumulate in tissue other than cancer tissue, is highly safe for a living body, and can be prepared by a simple and...
US20120022371 Compositions and methods for detecting and treating tumors containing acidic areas  
Improved compounds have been developed which are structured to be sequestered with very high specificity in acidic areas of tissues. When the compounds contain a radioisotope effective to report...
US20150110713 METHOD AND COMPOSITION FOR TREATING CANCER  
A method for treating cancer, preventing cancer or delaying the progression of a cancer in an animal or human comprising the step of: administering to the animal or the human having a cancer a...
US20130259805 DEVELOPMENT AND SCREENING OF CONTRAST AGENTS FOR IN VIVO IMAGING OF PARKINSON'S DISEASE  
The invention provides compounds and a method for imaging aggregated α-synuclein, e.g., Lewy bodies or Lewy neurites, in a tissue or organ.
US20110085974 SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY  
The present invention describes small molecule ligand-drug conjugates and methods of using the small molecule ligand-drug conjugates for targeted treatment of cancer in a patient in need thereof....
US20120251443 IMPLANTABLE CONTRAST AGENTS AND METHODS  
The present disclosure provides compositions and methods based on implantable contrast agents that are useful for imaging tissue and organs.
US20100316566 RADIOLABELED HEDGEHOG DERIVATIVES FOR IMAGING AND THERAPY  
The present invention concerns methods and compositions related to a chelator and a HHRT ligand. In specific embodiments of the invention the chelator is conjugated to the HHRT ligand. In another...
US20090226368 Androgen-Receptor (AR) Ligands for Use in the Treatment and Diagnosis of AR-Related Pathologies  
The present invention discloses novel compounds and compositions suitable for the treatment of androgen related pathologies. The invention also provides diagnostic compositions for the diagnosis...
US20100143248 METHODS FOR DIAGNOSING AND MONITORING TREATMENT OF ADHD BY ASSESSING THE DOPAMINE TRANSPORTER LEVEL  
A method of diagnosing attention deficient-hyperactivity disorder (ADHD) in a human patient by assessing the level of dopamine transporter in at least one region of the patient's central nervous...
US20130302246 COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET  
The present application provides compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reaction for rapid and specific covalent delivery of a “payload” to...

Matches 1 - 50 out of 371 1 2 3 4 5 6 7 8 >