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US20130058863 4-Protein Biomarker Panel for the Diagnosis of Lymphoma from Biospecimen  
A panel of lymphoma related biomarkers are provided. The panel allows the identification of a subject at risk for a lymphoma. Further provided are methods of optimizing therapeutic efficacy...
US20150078995 NANOPARTICLES/THERANOSTIC VEHICLES  
A nanotheranostic probe and its use to facilitate diagnoses, treatment and targeting of amyloid deposits are disclosed herein.
US20150037251 MAMMALIAN HOMOLOGUES OF FLOWER, THEIR USE IN CANCER DIAGNOSTICS, PREVENTION AND TREATMENT  
The invention relates inhibiting nucleic acids directed at mammalian homologues of the Drosophila fwe gene (Flower) and to antibodies against the respective proteins, and their use in diagnosing,...
US20130216475 METHODS AND COMPOSITIONS FOR PROTEIN LABELLING  
A modular platform is provided for rapid preparation of various water-soluble prosthetic groups capable to efficiently introduce 18F into proteins with 18F labelling reagents.
US20150147271 TARGETS FOR DIAGNOSIS, PROGNOSIS AND THERAPY OF ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROMES  
Methods are disclosed for diagnosis, prognosis and therapy of acute myeloid leukemia and myelodysplastic syndromes using interleukin 1 receptor accessory protein and other targets.
US20140170064 METHODS AND COMPOSITIONS FOR RADIOHALOGEN PROTEIN LABELING  
Methods and compositions are provided for labeling proteins with radiohalogen-label reagents. Radiohalogen-labeled proteins may be used for imaging studies, as therapeutics and in diagnostic...
US20110123444 Use of radioactively labelled molecule specifically binding to ED-B fibronection in a method of treatment of Hodgkin lymphoma  
The invention relates to the use of a radioactively labelled molecule specifically binding to ED-B fibronectin in a method of treatment for patients with Hodgkin lymphoma, in particular primary...
US20150104382 COMPOSITIONS AND METHODS FOR IDENTIFYING AND TARGETING CANCER CELLS OF ALIMENTARY CANAL ORIGIN  
Screening and diagnostic reagents, kits and methods for primary and or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20140056808 NEOANTIBODIES FOR DIAGNOSING TISSUE INJURY  
A method for diagnosing the development of a tissue injury in a subject comprising administering a sample of neoantibodies to the subject's tissue for the purpose of detecting the presence of...
US20120282175 Methods for Increasing Efficacy of FOLR1 Cancer Therapy  
Methods to improve the success of cancer therapies that target the human folate receptor 1 are provided. Kits comprising reagent useful in the methods are further provided.
US20150118154 METHODS FOR THE TREATMENT, THE PROGNOSTIC ASSESSMENT AND THE STAGING OF NON-SMALL CELL LUNG CANCER  
The present invention relates to methods for the treatment, the prognosis and the diagnosis of non-small cell lung cancer.
US20150044135 DUAL FUNCTION MARKERS FOR DIAGNOSTICS AND THERAPEUTICS FOR UPPER GASTROINTESTINAL TRACT PRECANCER  
The invention described herein relates to the detection, diagnosis, and treatment of intestinal metaplasias that develop to esophageal, gastric, and pancreatic adenocarcinoma. The stem cells and...
US20110250131 Antigens Associated with Endometriosis, Psoriatic Arthritis and Psoriasis  
Specific binding members that bind the ED-A isoform of fibronectin for use in methods of diagnosis, detection, imaging and/or treatment of endometriosis, and/or for use in delivery to the...
US20110027173 EPHRIN TYPE-A RECEPTOR 10 PROTEIN  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, head and neck cancer, kidney cancer,...
US20130064761 Methods for the treatment of tumors expressing TAT123 or naturally occurring variants thereof  
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
US20130064762 METHODS OF DETECTING AND TREATING CANCERS USING AUTOANTIBODIES  
This invention generally relates to a method of identifying pre-neoplastic or neoplastic tissue of a mammal by utilizing autoantibodies that detect the pre-neoplastic or neoplastic tissue. Also...
US20120114555 METHOD FOR TREATING IMMUNE DISORDERS  
The present invention relates to the treatment of B-cell mediated immune disorders such as rheumatoid arthritis, systemic lupus erythromatomus, diabetes mellitus, and multiple sclerosis. In...
US20110195019 NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 251P5G2 USEFUL IN TREATMENT AND DETECTION OF CANCER  
A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
US20110171127 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 162P1E6 USEFUL IN TREATMENT AND DETECTION OF CANCER  
A novel gene (designated 125P5C8) and its encoded protein, and variants thereof, are described wherein 125P5C8 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
US20100297006 NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 191P4D12(b) USEFUL IN TREATMENT AND DETECTION OF CANCER  
A novel gene 191P4D12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in...
US20100297005 NUCLEIC ACIDS AND CORRESPONDING PROTEIN ENTITLED 125P5C8 USEFUL IN TREATMENT AND DETECTION OF CANCER  
A novel gene 191P4D12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in...
US20140248211 METHOD OF TREATING CANCER  
The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and...
US20110002845 METHODS OF TREATING, DIAGNOSING OR DETECTING FGF21-ASSOCIATED DISORDERS  
The invention provides, inter alia, methods for treating cancer and vascular disease, compositions for treating cancer and vascular disease, and methods and compositions for diagnosing and/or...
US20150202255 TREATMENT AND DIAGNOSIS OF INFLAMMATORY DISORDERS AND HIV  
This invention concerns compositions and methods of treating or diagnosing inflammatory disorders and other disorders, as well as compositions and methods of treating HIV.
US20120263644 TREATMENT AND DIAGNOSIS OF INFLAMMATORY DISORDERS AND HIV  
This invention concerns compositions and methods of treating or diagnosing inflammatory disorders and other disorders, as well as compositions and methods of treating HIV.
US20110091378 Methods and Compositions for Treating Fibrosis Related Disorders Using IL-17 Antagonists  
The present invention relates methods and compositions for treating interleukin-17 (IL-17) related conditions, such as IL-17A or IL-17F, or muteins thereof in patients having fibrosis using IL-17...
US20130330275 MISFOLDED PROTEINS IN CANCER TREATMENT AND DIAGNOSIS  
Cancer cells are identified and inhibited using agents that bind to epitopes unique to misfolded forms of surface proteins presented by the cancer cells. In one embodiment, cancer cells are...
US20110305630 MISFOLDED PROTEINS IN CANCER TREATMENT AND DIAGNOSIS  
Cancer cells are identified and inhibited using agents that bind to epitopes unique to misfolded forms of surface proteins presented by the cancer cells. In one embodiment, cancer cells are...
US20150210770 THERAPEUTIC AND DIAGNOSTIC TARGET  
The present disclosure provides methods and compositions for treatment, screening, diagnosis and prognosis of cancer, such as bladder cancer, esophagus cancer, head and neck cancer, lung cancer,...
US20120121505 THERAPEUTIC COMPOSITIONS AND METHODS  
The present application provides novel binding proteins, including human binding proteins that specifically bind to the human ErbB2.
US20110236307 IN VIVO IMAGING METHOD  
The present invention provides an in vivo imaging method that facilitates the diagnosis of Parkinson's disease (PD) at an early stage. Early diagnosis is particularly advantageous as...
US20140255301 METHODS FOR DETECTING NEURODEGENERATIVE DISEASES OR DISORDERS  
Methods of identifying, diagnosing, and prognosing a neurodegenerative disease, or disorder, are provided. Also provided are methods for determining whether a neuron is at risk or is undergoing...
US20140193332 Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders  
The present invention is directed to compositions of matter useful for the diagnosis and treatment of inflammatory bowel diseases in mammals and to methods of using those compositions of matter...
US20120308477 BRIEF RADIOIMMUNOTHERAPY  
The present invention relates to a method of treating a subject having a cancer in a body cavity characterized in that it comprises the steps of: administering in said body cavity of the subject...
US20140193333 THERAPEUTIC AND DIAGNOSTIC TARGET  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia, breast cancer,...
US20130164215 COMPOSITIONS AND METHODS FOR DETECTING, DIAGNOSING, AND TREATING CANCER  
The present invention provides compositions and methods useful for diagnosing, treating, and preventing cancer, particularly ovarian cancer and uterine cancer, based on the discovery that the...
US20120315216 Compositions and Methods for Treating and Diagnosing Cancer  
The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides gene expression profiles associated...
US20150110714 Diagnosis and Treatment of Cancer Expressing ILT3 or ILT3 Ligand  
The present invention relates to methods of using the expression of ILTL3 ligand or ILT3 on certain types of cancer cells as a diagnostic tool. Methods are provided for treating ILT3-ligand...
US20120087860 METHODS FOR IN VIVO CANCER DETECTION, DIAGNOSIS AND THERAPY USING MULTIDOMAIN BIOTAGS  
In another embodiment, a method for detecting and/or diagnosing a cancer in a subject is provided. The method may include administering an effective dose of a biotag to a subject, or...
US20110262349 Methods and Agents for the Diagnosis and Treatment of Hepatocellular Carcinoma  
The present invention relates to methods of diagnosing, and methods of treating, hepatocellular carcinoma in a subject. The invention also relates to polypeptide antagonists of PLVAP proteins,...
US20140322131 Methods and Agents for the Diagnosis and Treatment of Hepatocellular Carcinoma  
The present invention relates to methods of diagnosing and methods of treating hepatocellular carcinoma in a subject. The invention also relates to antagonists of PLVAP proteins, such as...
US20110085973 Methods and Agents for the Diagnosis and Treatment of Hepatocellular Carcinoma  
The present invention relates to methods of diagnosing, and methods of treating, hepatocellular carcinoma in a subject. The invention also relates to antagonists of PLVAP proteins, such as...
US20140308202 NF-KB GENE SIGNATURE PREDICTS PROSTATE AND BREAST CANCER PROGRESSION  
The present invention is drawn to methods of assessing hormonally-regulated cancers such as prostate and breast, by examining the expression of particular genes disregulated in this disease state.
US20140322130 SPECIFIC BINDING PROTEINS AND USES THEREOF  
The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to EGFR on tumor cells that overexpress EGFR, and on tumor cells that express...
US20120230913 PROTEIN NANOPARTICLE DISPERSIONS  
Provided herein, inter alia, are protein dispersions comprising dense protein nanoclusters and methods of making the. Upon dilution, the clusters may reversibly dissociate into native protein...
US20120282177 ROR1 as Therapeutic and Diagnostic Target  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of cancer including bladder cancer, breast cancer, colorectal cancer, head and neck...
US20110014119 Methods for Manipulating Phagocytosis Mediated by CD47  
Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc.
US20110059011 DIAGNOSIS AND TREATMENT OF DISEASED AND DAMAGED TISSUE  
The present invention relates to the diagnosis and treatment of leukemia and cardiovascular disease, as well as the detection of diseased and damaged tissue. More particularly, the present...
US20110123443 PANCREATIC BETA-CELL MASS BIOMARKER  
A biomarker for pancreatic beta-cell mass comprising measuring the levels of CFC1 in the serum of a subject is described. The biomarker provides a noninvasive means for measuring pancreatic beta...
US20110085972 NANOTUBES FOR CANCER THERAPY AND DIAGNOSTICS  
The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT),...