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US20140050385 IDENTIFYING LOCATION BIOMARKERS  
A method performed by one or more processing devices includes retrieving data for a protein in a tissue type in a first state and for the protein in the tissue type in a second state; determining,...
US20100177950 Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition  
Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment,...
US20140050384 Context Driven Image Mining to Generate Image-Based Biomarkers  
An image-based biomarker is generated using image features obtained through object-oriented image analysis of medical images. The values of a first subset of image features are measured and...
US20130094749 MODEL-BASED CORONARY ARTERY CALCIUM SCORING  
A system and method are provided for model-based coronary artery calcium (CAC) scoring. A model image of a heart region is aligned with an image of a patient's heart region in order to more easily...
US20120201445 COMPUTER AIDED DIAGNOSTIC SYSTEM INCORPORATING APPEARANCE ANALYSIS FOR DIAGNOSING MALIGNANT LUNG NODULES  
A computer aided diagnostic system and automated method diagnose lung cancer through modeling and analyzing the visual appearance of pulmonary nodules. A learned appearance model used in such...
US20130315465 Whole Tissue Classifier for Histology Biopsy Slides  
Disclosed is a computer implemented method for fully automated tissue diagnosis that trains a region of interest (ROI) classifier in a supervised manner, wherein labels are given only at a tissue...
US20150030123 SYSTEM FOR NON-INVASIVE CLASSIFICATION OF DIFFERENT TYPES OF MICRO-CALCIFICATIONS IN HUMAN TISSUE  
A non-invasive method distinguishes between two types of micro-calcification by x-ray imaging in mammography. Two major types of micro-calcifications are found and confirmed by histopathology and...
US20110262025 Cosmetic Compositions and Methods for Maintaining and Improving Barrier Function of the Stratum Corneum and to Reduce the Visible Signs of Aging in Skin  
Gene panels, biomarker panels and microarrays relating to lipid formation in stratum corneum of human skin as a function of extrinsic and/or intrinsic aging conditions, and methods for assessing...
US20110169937 MODE OF ACTION SCREENING METHOD  
Certain aspects of this disclosure relate to a screening method. In general terms, the screening assay comprises contacting test cells with a test compound to provide contacted test cells,...
US20130156287 OBSERVATION DEVICE, OBSERVATION PROGRAM, AND OBSERVATION SYSTEM  
An observation device (1) is provided with: a general observation unit (10) for observing sample cells by observing an entire container (C) containing the cells and a culture solution; and a...
US20150086104 METHOD AND SYSTEM FOR SKIN CARE CONSULTATION  
Described herein are materials and methods for evaluating skin quality and providing customized, concierge skin consultation to consumers. In various aspects, the disclosure includes a method...
US20120082363 Method for Displaying a Vessel of a Particular Biological Subject  
A method for displaying a vessel of a particular biological subject is proposed. The particular object is inserted into the vessel. The deformation of the vessel is predicted by an inserted object...
US20120315620 Method and Apparatus for Discriminating Undifferentiated Pluripotent Stem Cells, and Automated Culture Method and System  
Provided are a method capable of discriminating between a colony of differentiated pluripotent stem cells and a colony of undifferentiated pluripotent stem cells, and a method for automatically...
US20120063664 INERTIAL PARTICLE FOCUSING FLOW CYTOMETER  
A flow cytometry system includes an inertial particle focusing device including a plurality of substantially parallel microchannels formed in a substrate, each microchannel having a width to...
US20120114217 TIME RESOLVED DIGITAL SUBTRACTION ANGIOGRAPHY PERFUSION MEASUREMENT METHOD, APPARATUS AND SYSTEM  
A method is disclosed of providing time dependent three dimensional imaging of a region of a patient comprising blood vessels in a perfusion bed.
US20120237107 SYSTEM AND METHODS FOR DIGITAL EVALUATION OF CELLBLOCK PREPARATIONS  
Digital evaluation of cellblock preparations to determine the type and extent of disease in order to identify the best approach for treatment without the need for additional testing or sampling.
US20150036912 METHOD FOR QUANTIFYING THE MORPHOLOGICAL REGULARITY DEGREE OF THE PELLUCID ZONE IN EMBRYOS AND OOCYTES  
The present invention refers to a method for calculating a shape factor indicative of the evenness of the pellucid zone thickness of a biological structure and to a method for evaluating the...
US20100121738 METHOD FOR PROVIDING PROTEIN MICROARRAYS  
The present application relates to methods for providing a protein microarray product and related products and services to a customer, methods, kits, and systems for labeling a probe for a protein...
US20150169985 AUTOMATED EPITHELIAL NUCLEI SEGMENTATION FOR COMPUTATIONAL DISEASE DETECTION ALGORITHMS  
In aspects, the subject innovation can comprise systems and methods capable of automatically labeling cell nuclei (e.g., epithelial nuclei) in tissue images containing multiple cell types. The...
US20110110577 MATHEMATICAL IMAGE ANALYSIS BASED CELL REPROGRAMMING WITH APPLICATIONS FOR EPIGENETIC AND NON-EPIGENETIC BASE INDUCED PLURIPOTENT STEM CELL DERIVATION  
Mathematical and statistical image analysis methods and systems are applied to enhance and refine the process of reprogramming cells, for example, to modify cells from patients into custom-matched...
US20150003716 HISTOLOGY RECOGNITION TO AUTOMATICALLY SCORE AND QUANTIFY CANCER GRADES AND INDIVIDUAL USER DIGITAL WHOLE HISTOLOGICAL IMAGING DEVICE  
Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The...
US20140294279 Quantitatively Characterizing Disease Morphology With Cell Orientation Entropy  
Apparatus, methods, and other embodiments associated with objectively predicting biochemical recurrence (BCR) with cell orientation entropy (COrE) are described. One example apparatus includes a...
US20140205173 METHOD AND SYSTEMS FOR CELL-LEVEL FISH DOT COUNTING  
The invention relates to a computer implemented method and systems for cell level fish dot counting. FISH (fluorescence in situ hybridization) dot counting is the process of enumerating...
US20150102216 Classification Generation Method Using Combination of Mini-Classifiers with Regularization and Uses Thereof  
A method for classifier generation includes a step of obtaining data for classification of a multitude of samples, the data for each of the samples consisting of a multitude of physical...
US20120243769 QUANTIFYING CELL DEATH  
The invention relates to methods of diagnosis, particularly methods of staging and diagnosing neurodegenerative diseases using images of cell death in the eye.
US20120219205 NONINVASIVE ASSESSMENT OF KERATINOCYTES  
Embodiments herein provide methods for noninvasive assessment of keratinocytes. Digital imaging and processing of gray-levels are used to identify cells. More specifically, embodiments provide an...
US20140377753 SYSTEM FOR DETECTING GENES IN TISSUE SAMPLES  
A computer-based specimen analyzer (10) is configured to detect a level of expression of genes in a cell sample by detecting dots that represent differently stained genes and chromosomes in a...
US20130202182 METHODS AND SYSTEMS FOR ESTIMATING GENETIC CHARACTERISTICS FROM BIOMETRIC MEASUREMENTS  
Methods and devices are disclosed for collecting fingerprint and genetic information from an individual during a single collection session. A skin site is illuminated by direct imaging of the skin...
US20120219204 PREDICTING TOXICITY OF A COMPOUND OVER A RANGE OF CONCENTRATIONS  
A method of predicting hepatotoxicity of a compound. The method includes imaging cells of hepatic origin positioned within a plurality of containers to obtain imaged cellular targets, each...
US20130294676 Diagnostic and Prognostic Histopathology System Using Morphometric Indices  
Determining at least one of a prognosis or a therapy for a patient based on a stained tissue section of the patient. An image of a stained tissue section of a patient is processed by a processing...
US20150254494 Histogram of Hosoya Index (HoH) Features For Quantitative Histomorphometry  
Methods, apparatus, and other embodiments associated with classifying a region of cancerous tissue using a Histogram of Hosoya are described. One example apparatus includes a set of logics that...
US20140003702 DETERMINATION OF SPATIAL PROXIMITY BETWEEN FEATURES OF INTEREST IN BIOLOGICAL TISSUE  
Exemplary embodiments enable determination of spatial proximity between two or more features in biological tissue. An exemplary method includes identifying a morphological feature in an image of...
US20130336567 INTERNAL FOCUS REFERENCE BEADS FOR IMAGING CYTOMETRY  
The invention generally relates to analytical and monitoring systems useful for analyzing and measuring cells and biological samples. More particularly, the invention provides systems and methods...
US20130170728 PROCESS AND SYSTEM FOR ANALYZING THE EXPRESSION OF BIOMARKERS IN A CELL  
The invention relates generally to a process of analyzing and visualizing the expression of biomarkers in an individual cell wherein the cell is examined to develop patterns of expression by using...
US20110091091 PROCESS AND SYSTEM FOR ANALYZING THE EXPRESSION OF BIOMARKERS IN CELLS  
The invention relates generally to a process of analyzing and visualizing the expression of biomarkers in individual cells wherein the cells are examined to develop patterns of expression by using...
US20110188728 METHODS OF GENERATING TROPHECTODERM AND NEURECTODERM FROM HUMAN EMBRYONIC STEM CELLS  
Methods for inducing differentiation of stem cells into trophectoderm, neurectoderm, or progeny cells thereof are described, and mathematical and statistical image analysis methods and systems,...
US20130064441 Methods and Apparatus for Fast Identification of Relevant Features for Classification or Regression  
In various embodiments, methods and apparatus are provided for automated selection of features of cells useful for classifying cell phenotype. The methods include determining a signal-to-noise...
US20110182494 Method Of Identification Of Cancerous And Normal Cells  
A method is described for distinguishing between cancerous and normal human cells. The method includes collecting cells; preparing cells for scanning; scanning of the prepared cells by means of...
US20120164133 METHODS OF IDENTIFYING AN ORGANISM  
This disclosure features methods of identifying an organism. The methods include: (a) obtaining a nucleic acid sample from an organism; (b) imaging said nucleic acid; (c) obtaining a restriction...
US20120321169 Shape Based Conditional Random Fields for Segmenting Intracranial Aneurysms  
A method for segmenting intracranial aneurysms in digital medical images includes extracting a mesh representing a vessel surface from a volumetric digital image, the mesh comprising a set of...
US20120275681 DEVICE FOR HARVESTING BACTERIAL COLONY AND METHOD THEREFOR  
When multiple kinds of bacterial colonies are present in a petri dish and, for example, a drug tolerance is to be measured, harvesting of mixed colonies of different types of bacteria makes it...
US20120195488 Methods and Compositions Related to Cellular Assays  
The present invention relates generally to the fields of molecular biology and cancer. More specifically, the invention concerns methods and compositions useful for diagnosing and assessing a...
US20100021953 Method for Identifying an Agent that Modulates Arginine Transport in a Chondrocyte  
The present invention relates to an assay method for identifying an agent that modulates arginine transport in a chondrocyte comprising the steps of: (a) identifying an agent that modulates the...
US20130194410 CELL OCCUPANCY MEASUREMENT  
A method for determining cell occupancy, confluency and cell migration in a cell culture, comprising receiving data related to pixel intensity in an image acquired of the cell culture, and...
US20130251234 METHOD FOR IMAGING AND DIFFERENTIAL ANALYSIS OF CELLS  
Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods...
US20130202183 METHOD FOR IMAGING AND DIFFERENTIAL ANALYSIS OF CELLS  
Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods...
US20120328177 Method for Imaging and Differential Analysis of Cells  
Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods...
US20110280467 METHOD FOR IMAGING AND DIFFERENTIAL ANALYSIS OF CELLS  
Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods...
US20150219545 PORTAL AND METHOD FOR MANAGEMENT OF DIALYSIS THERAPY  
System and method for point-of-care monitoring of neutrophils in a peritoneal dialysis sample with the use of a microfluidic system. The immunoassay based chip is configured to bound neutrophils...
US20120177611 Elastic substrates and methods of use in cell manipulation and culture  
Methods are provided for the ex vivo manipulation of cells, stem cells and other reproductive cells, by manipulating the cells in a container or device comprising an elastic substrate, wherein the...